Palaeoproteomics | Enrico Cappellini group

The introduction of revolutionary analytical approaches, most notably high-throughput mass spectrometry (MS)-based protein sequencing, allowed confident sequencing of ancient proteins. This new, robust and reliable approach, we call palaeoproteomics, already demonstrated it can provide very innovative results in the study, diagnostics, and protection of cultural heritage collections. Ancient proteins are quantitatively more abundant and persist up to 100 times longer than DNA. In the last few years, the number of peer-reviewed articles based on palaeoproteomic investigation has increased, reaching high-profile journals, and attracting scientific feature articles and broad-audience media. It can be envisaged that this trend will be maintained in the future, as the availability of a robust and reliable technological platform opens the gates for a long phase of significant, incremental development of processes and optimisation of productivity.