Authentication and assessment of contamination in ancient DNA
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- Renaud-AuthenticationChapter-Accepted
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Contamination from both present-day humans and postmortem microbial sources is a common challenge in ancient DNA studies. Here we present a suite of tools to assist in the assessment of contamination in ancient DNA data sets. These tools perform standard tests of authenticity of ancient DNA data including detecting the presence of postmortem damage signatures in sequence alignments and quantifying the amount of present-day human contamination.
Original language | English |
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Title of host publication | Ancient DNA : Methods and Protocols |
Editors | Beth Shapiro, Axel Barlow, Peter D. Heintzman, Michael Hofreiter, Johanna L. A. Paijmans, André E. R. Soares |
Number of pages | 32 |
Publisher | Humana Press |
Publication date | 2019 |
Edition | 2. ed. |
Pages | 163-194 |
Chapter | 17 |
ISBN (Print) | 978-1-4939-9175-4 |
ISBN (Electronic) | 978-1-4939-9176-1 |
DOIs | |
Publication status | Published - 2019 |
Series | Methods in Molecular Biology |
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Volume | 1963 |
ISSN | 1064-3745 |
- Ancient DNA, Contamination, DICE, mapDamage2.0, Postmortem damage, Schmutzi
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