Shyam Gopalakrishnan

Shyam Gopalakrishnan

Associate Professor

Member of:


    1. 2023
    2. Published

      Ancient DNA reveals genetic admixture in China during tiger evolution

      Sun, X., Liu, Y. C., Tiunov, M. P., Gimranov, D. O., Zhuang, Y., Han, Y., Driscoll, C. A., Pang, Y., Li, C., Pan, Y., Velasco, M. S., Gopalakrishnan, S., Yang, R. Z., Li, B. G., Jin, K., Xu, X., Uphyrkina, O., Huang, Y., Wu, X. H., Gilbert, M. T. P. & 3 others, O’Brien, S. J., Yamaguchi, N. & Luo, S., 2023, In: Nature Ecology and Evolution. 7, 11, p. 1914-1929 29 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Conservation implications of elucidating the Korean wolf taxonomic ambiguity through whole-genome sequencing

      Hernández-Alonso, G., Ramos-Madrigal, J., Sun, X., Scharff-Olsen, C. H., Sinding, M. H. S., Martins, N. F., Ciucani, M. M., Mak, S. S. T., Lanigan, L. T., Clausen, C. G., Bhak, J., Jeon, S., Kim, C., Eo, K. Y., Cho, S. H., Boldgiv, B., Gantulga, G., Unudbayasgalan, Z., Kosintsev, P. A., Stenøien, H. K. & 2 others, Gilbert, M Thomas P & Gopalakrishnan, Shyam, 2023, In: Ecology and Evolution. 13, 8, 15 p., e10404.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Dealing with dimensionality: the application of machine learning to multi-omics data

      Feldner-Busztin, D., Nisantzis, P. F., Edmunds, S. J., Boza, G., Racimo, Fernando, Gopalakrishnan, Shyam, Limborg, Morten Tønsberg, Lahti, L. & de Polavieja, G. G., 2023, In: Bioinformatics. 39, 2, 8 p., btad021.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      HaploCart: Human mtDNA haplogroup classification using a pangenomic reference graph

      Rubin, J. D., Vogel, N. A., Gopalakrishnan, Shyam, Sackett, P. W. & Renaud, G., 2023, In: PLOS Computational Biology. 19, 6, 27 p., e1011148.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Redefining the Evolutionary History of the Rock Dove, Columba livia, Using Whole Genome Sequences

      Hernández Alonso, Germán, Ramos Madrigal, Jazmin, van Grouw, H., Ciucani, Marta Maria, Cavill, Emily Louisa, Sinding, Mikkel Holger Strander, Gopalakrishnan, Shyam, Antunes Pacheco, George & Gilbert, M Thomas P, 2023, In: Molecular Biology and Evolution. 40, 11, 17 p., msad243.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      The ancestry and geographical origins of St Helena's liberated Africans

      Sandoval-Velasco, Marcela, Jagadeesan, A., Ramos Madrigal, Jazmin, Ávila-Arcos, M. C., Fortes-Lima, C. A., Watson, J., Johannesdóttir, E., Cruz-Dávalos, D. I., Gopalakrishnan, Shyam, Moreno Mayar, J. Víctor, Niemann, Jonas, Renaud, G., Brown, K. A. R., Bennett, H., Pearson, A., Helgason, A., Gilbert, M Thomas P & Schroeder, Hannes, 2023, In: American Journal of Human Genetics. 110, 9, p. 1590-1599 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      The extinct Sicilian wolf shows a complex history of isolation and admixture with ancient dogs

      Ciucani, M. M., Ramos-Madrigal, J., Hernández-Alonso, G., Carmagnini, A., Aninta, S. G., Sun, X., Scharff-Olsen, C. H., Lanigan, L. T., Fracasso, I., Clausen, C. G., Aspi, J., Kojola, I., Baltrūnaitė, L., Balčiauskas, L., Moore, J., Åkesson, M., Saarma, U., Hindrikson, M., Hulva, P., Bolfíková, B. Č. & 19 others, Nowak, C., Godinho, R., Smith, S., Paule, L., Nowak, S., Mysłajek, R. W., Lo Brutto, S., Ciucci, P., Boitani, L., Vernesi, C., Stenøien, H. K., Smith, O., Frantz, L., Rossi, L., Angelici, F. M., Cilli, E., Sinding, Mikkel Holger Strander, Gilbert, M Thomas P & Gopalakrishnan, Shyam, 2023, In: iScience. 26, 8, 22 p., 107307.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      The genetic history of Scandinavia from the Roman Iron Age to the present

      Rodríguez-Varela, R., Moore, K. H. S., Ebenesersdóttir, S. S., Kilinc, G. M., Kjellström, A., Papmehl-Dufay, L., Alfsdotter, C., Berglund, B., Alrawi, L., Kashuba, N., Sobrado, V., Lagerholm, V. K., Gilbert, E., Cavalleri, G. L., Hovig, E., Kockum, I., Olsson, T., Alfredsson, L., Hansen, T. F., Werge, T. & 24 others, Munters, A. R., Bernhardsson, C., Skar, B., Christophersen, A., Turner-Walker, G., Gopalakrishnan, Shyam, Daskalaki, E., Omrak, A., Pérez-Ramallo, P., Skoglund, P., Girdland-Flink, L., Gunnarsson, F., Hedenstierna-Jonson, C., Gilbert, M Thomas P, Lidén, K., Jakobsson, M., Einarsson, L., Victor, H., Krzewińska, M., Zachrisson, T., Storå, J., Stefánsson, K., Helgason, A. & Götherström, A., 2023, In: Cell. 186, 1, p. 32-46.e19

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      The history of Coast Salish “woolly dogs” revealed by ancient genomics and Indigenous Knowledge

      Lin, A. T., Hammond-Kaarremaa, L., Liu, H-L., Stantis, C., McKechnie, I., Pavel, M., Pavel, S. S. M., Wyss, S. S., Sparrow, D. Q., Carr, K., Aninta, S. G., Perri, A., Hartt, J., Bergström, A., Carmagnini, A., Charlton, S., Dalén, L., Feuerborn, T. R., France, C. A. M., Gopalakrishnan, S. & 13 others, Grimes, V., Harris, A., Kavich, G., Sacks, B. N., Sinding, Mikkel Holger Strander, Skoglund, P., Stanton, D. W. G., Ostrander, E. A., Larson, G., Armstrong, C. G., Frantz, L. A. F., Hawkins, M. T. R. & Kistler, L., 2023, In: Science. 382, 6676, p. 1303-1309 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Uncovering neutral and adaptive genomic differentiation among European perch with brackish water and freshwater origin in the western Baltic Sea region

      Skovrind, Mikkel, Antunes Pacheco, George, Christensen, E. A. F., Gopalakrishnan, Shyam, Fietz, K., Holm-Hansen, T. H., Vieira, Filipe Garrett, Krag, M. A., Carl, Henrik, Gilbert, M Thomas P, Olsen, Morten Tange & Møller, Peter Rask, 2023, In: Fisheries Research. 268, 11 p., 106846.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. 2022
    13. Published
    14. Published

      Analysis of independent cohorts of outbred CFW mice reveals novel loci for behavioral and physiological traits and identifies factors determining reproducibility

      Zou, J., Gopalakrishnan, Shyam, Parker, C. C., Nicod, J., Mott, R., Cai, N., Lionikas, A., Davies, R. W., Palmer, A. A. & Flint, J., 2022, In: G3: Genes, Genomes, Genetics. 12, 1, 13 p., jkab394.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Ancient Maltese genomes and the genetic geography of Neolithic Europe

      Ariano, B., Mattiangeli, V., Breslin, E. M., Parkinson, E. W., McLaughlin, T. R., Thompson, J. E., Power, R. K., Stock, J. T., Mercieca-Spiteri, B., Stoddart, S., Malone, C., Gopalakrishnan, Shyam, Cassidy, L. M. & Bradley, D. G., 2022, In: Current Biology. 32, 12, p. 2668-2680.e6

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Benchmarking freely available HLA typing algorithms across varying genes, coverages and typing resolutions

      Thuesen, N. H., Klausen, M. S., Gopalakrishnan, Shyam, Trolle, T. & Renaud, Gabriel, 2022, In: Frontiers in Immunology. 13, 15 p., 987655.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Conservation genomics of the endangered Seychelles Magpie-Robin (Copsychus sechellarum): a unique insight into the history of a precious endemic bird

      Cavill, Emily Louisa, Gopalakrishnan, Shyam, Puetz, Lara Christine, Ribeiro, Â. M., Mak, Sarah Siu Tze, Rodrigues da Fonseca, Rute Andreia, Antunes Pacheco, George, Dunlop, B., Accouche, W., Shah, N., Zora, A., Calabrese, L., Genner, M., Jones, G., Guo, C., KU, thw266 & Gilbert, M Thomas P, 2022, In: Ibis. 164, 2, p. 396-410 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Grey wolf genomic history reveals a dual ancestry of dogs

      Bergström, A., Stanton, D. W. G., Taron, U. H., Frantz, L., Sinding, M. H. S., Ersmark, E., Pfrengle, S., Cassatt-Johnstone, M., Lebrasseur, O., Girdland-Flink, L., Fernandes, D. M., Ollivier, M., Speidel, L., Gopalakrishnan, S., Westbury, M. V., Ramos-Madrigal, J., Feuerborn, T. R., Reiter, E., Gretzinger, J., Münzel, S. C. & 61 others, Swali, P., Conard, N. J., Carøe, C., Haile, James Seymour, Linderholm, A., Androsov, S., Barnes, I., Baumann, C., Benecke, N., Bocherens, H., Brace, S., Carden, R. F., Drucker, D. G., Fedorov, S., Gasparik, M., Germonpré, M., Grigoriev, S., Groves, P., Hertwig, S. T., Ivanova, V. V., Janssens, L., Jennings, R. P., Kasparov, A. K., Kirillova, I. V., Kurmaniyazov, I., Kuzmin, Y. V., Kosintsev, P. A., Lázničková-Galetová, M., Leduc, C., Nikolskiy, P., Nussbaumer, M., O’Drisceoil, C., Orlando, L., Outram, A., Pavlova, E. Y., Perri, A. R., Pilot, M., Pitulko, V. V., Plotnikov, V. V., Protopopov, A. V., Rehazek, A., Sablin, M., Seguin-Orlando, A., Storå, J., Verjux, C., Zaibert, V. F., Zazula, G., Crombé, P., Hansen, Anders Johannes, Willerslev, Eske, Leonard, J. A., Götherström, A., Pinhasi, R., Schuenemann, V. J., Hofreiter, M., Gilbert, M Thomas P, Shapiro, B., Larson, G., Krause, J., Dalén, L. & Skoglund, P., 2022, In: Nature. 607, 7918, p. 313-320

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Pervasive Phylogenomic Incongruence Underlies Evolutionary Relationships in Eyebrights (Euphrasia, Orobanchaceae)

      Garrett, P., Becher, H., Gussarova, G., dePamphilis, C. W., Ness, R. W., Gopalakrishnan, Shyam & Twyford, A. D., 2022, In: Frontiers in Plant Science. 13, 16 p., 869583.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Probing the genomic limits of de-extinction in the Christmas Island rat

      Lin, J., Duchene, David, Carøe, C., Smith, O., Ciucani, M. M., Niemann, Jonas, Richmond, D., Greenwood, A. D., MacPhee, R., KU, thw266, Gopalakrishnan, Shyam & Gilbert, M Thomas P, 2022, In: Current Biology. 32, 7, p. 1650-1656.e3

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      The population genomic legacy of the second plague pandemic

      Gopalakrishnan, S., Ebenesersdóttir, S. S., Lundstrøm, I. K. C., Turner-Walker, G., Moore, K. H. S., Luisi, P., Margaryan, A., Martin, M. D., Ellegaard, M. R., Magnússon, Ó., Sigurðsson, Á., Snorradóttir, S., Magnúsdóttir, D. N., Laffoon, J. E., van Dorp, L., Liu, X., Moltke, I., Ávila-Arcos, M. C., Schraiber, J. G., Rasmussen, S. & 40 others, Juan, D., Gelabert, P., de-Dios, T., Fotaki, Anna Katerina, Iraeta Orbegozo, Miren, Vågene, Åshild Joanne, Denham, S. D., Christophersen, A., Stenøien, H. K., Vieira, Filipe Garrett, Liu, Shanlin, Günther, T., Kivisild, T., Moseng, O. G., Skar, B., Cheung, C., Sandoval-Velasco, Marcela, Wales, N., Schroeder, Hannes, Campos, P. F., Guðmundsdóttir, V. B., Sicheritz-Pontén, Thomas, Petersen, Bent, Halgunset, J., Gilbert, E., Cavalleri, G. L., Hovig, E., Kockum, I., Olsson, T., Alfredsson, L., Hansen, Thomas Folkmann, Werge, Thomas, Willerslev, Eske, Balloux, F., Marques-Bonet, T., Lalueza-Fox, C., Nielsen, Rasmus, Stefánsson, K., Helgason, A. & Gilbert, M Thomas P, 2022, In: Current Biology. 32, 21, p. 4743-4751.e6

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      The rise of genomics in snake venom research: recent advances and future perspectives

      Rao, W. Q., Kalogeropoulos, K., Allentoft, Morten Erik, Gopalakrishnan, Shyam, Zhao, W., Workman, C. T., Knudsen, C., Jiménez-Mena, B., Seneci, L., Mousavi-Derazmahalleh, M., Jenkins, T. P., Rivera-de-Torre, E., Liu, S. Q. & Laustsen, A. H., 2022, In: GigaScience. 11, 16 p., giac024.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      Travel Tales of a Worldwide Weed: Genomic Signatures of Plantago major L. Reveal Distinct Genotypic Groups With Links to Colonial Trade Routes

      Iwanycki Ahlstrand, N., Gopalakrishnan, S., Vieira, F. G., Bieker, V. C., Meudt, H. M., Dunbar-Co, S., Rothfels, C. J., Martinez-Swatson, K. A., Maldonado, C., Hassemer, G., Shipunov, A., Bowers, M. D., Gardner, E., Xu, M., Ghorbani, A., Amano, M., Grace, O. M., Pringle, J. S., Bishop, M., Manzanilla, V. & 18 others, Cotrim, H., Blaney, S., Zubov, D., Choi, H., Yesil, Y., Bennett, B., Vimolmangkang, S., El-Seedi, H. R., Staub, P. O., Li, Z., Boldbaatar, D., Hislop, M., Caddy, L. J., Muasya, A. M., Saslis-Lagoudakis, C. H., Gilbert, M Thomas P, Zerega, N. J. C. & Rønsted, Nina, 2022, In: Frontiers in Plant Science. 13, 16 p., 838166.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Uncovering the genomic basis of an extraordinary plant invasion

      Bieker, V. C., Battlay, P., Petersen, B., Sun, X., Wilson, J., Brealey, J. C., Bretagnolle, F., Nurkowski, K., Lee, C., Barreiro, F. S., Owens, G. L., Lee, J. Y., Kellner, F. L., van Boheeman, L., Gopalakrishnan, S., Gaudeul, M., Mueller-Schaerer, H., Lommen, S., Karrer, G., Chauvel, B. & 8 others, Sun, Y., Kostantinovic, B., Dalén, L., Poczai, P., Rieseberg, L. H., Gilbert, M Thomas P, Hodgins, K. A. & Martin, M. D., 2022, In: Science Advances. 8, 34, 18 p., eabo5115.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. 2021
    26. Published

      Circumpolar phylogeography and demographic history of beluga whales reflect past climatic fluctuations

      Skovrind, M., Louis, M., Westbury, M. V., Garilao, C., Kaschner, K., Castruita, J. A. S., Gopalakrishnan, S., Knudsen, S. W., Haile, J. S., Dalén, L., Meshchersky, I. G., Shpak, O. V., Glazov, D. M., Rozhnov, V. V., Litovka, D. I., Krasnova, V. V., Chernetsky, A. D., Bel'kovich, V. M., Lydersen, C., Kovacs, K. M. & 4 others, Heide-Jørgensen, M. P., Postma, L., Ferguson, S. H. & Lorenzen, Eline, Jun 2021, In: Molecular Ecology. 30, 11, p. 2543-2559 17 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      Ancient and modern genomes unravel the evolutionary history of the rhinoceros family

      Liu, S., Westbury, M. V., Dussex, N., Mitchell, K. J., Sinding, M. H. S., Heintzman, P. D., Duchêne, D. A., Kapp, J. D., von Seth, J., Heiniger, H., Sánchez-Barreiro, F., Margaryan, A., André-Olsen, R., De Cahsan, B., Meng, G., Yang, C., Chen, L., van der Valk, T., Moodley, Y., Rookmaaker, K. & 19 others, Bruford, M. W., Ryder, O., Steiner, C., Sonsbeek, L. G. R. B., Vartanyan, S., Guo, C., Cooper, A., Kosintsev, P., Kirillova, I., Lister, A. M., Marques-Bonet, T., Gopalakrishnan, Shyam, Dunn, Rob, Lorenzen, Eline, Shapiro, B., KU, thw266, Antoine, P. O., Dalén, L. & Gilbert, M Thomas P, 2021, In: Cell. 184, 19, p. 4874-4885.e16

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

      Biodiversity Soup II: A bulk-sample metabarcoding pipeline emphasizing error reduction

      Yang, C., Bohmann, Kristine, Wang, X., Cai, W., Wales, N., Ding, Z., Gopalakrishnan, Shyam & Yu, D. W., 2021, In: Methods in Ecology and Evolution. 12, 7, p. 1252-1264 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

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    ID: 140603020