Concordant divergence of mitogenomes and a mitonuclear gene cluster in bird lineages inhabiting different climates

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Concordant divergence of mitogenomes and a mitonuclear gene cluster in bird lineages inhabiting different climates. / Morales, Hernán E.; Pavlova, Alexandra; Amos, Nevil; Major, Richard; Kilian, Andrzej; Greening, Chris; Sunnucks, Paul.

In: Nature Ecology & Evolution, Vol. 2, No. 8, 2018, p. 1258-1267.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Morales, HE, Pavlova, A, Amos, N, Major, R, Kilian, A, Greening, C & Sunnucks, P 2018, 'Concordant divergence of mitogenomes and a mitonuclear gene cluster in bird lineages inhabiting different climates', Nature Ecology & Evolution, vol. 2, no. 8, pp. 1258-1267. https://doi.org/10.1038/s41559-018-0606-3

APA

Morales, H. E., Pavlova, A., Amos, N., Major, R., Kilian, A., Greening, C., & Sunnucks, P. (2018). Concordant divergence of mitogenomes and a mitonuclear gene cluster in bird lineages inhabiting different climates. Nature Ecology & Evolution, 2(8), 1258-1267. https://doi.org/10.1038/s41559-018-0606-3

Vancouver

Morales HE, Pavlova A, Amos N, Major R, Kilian A, Greening C et al. Concordant divergence of mitogenomes and a mitonuclear gene cluster in bird lineages inhabiting different climates. Nature Ecology & Evolution. 2018;2(8):1258-1267. https://doi.org/10.1038/s41559-018-0606-3

Author

Morales, Hernán E. ; Pavlova, Alexandra ; Amos, Nevil ; Major, Richard ; Kilian, Andrzej ; Greening, Chris ; Sunnucks, Paul. / Concordant divergence of mitogenomes and a mitonuclear gene cluster in bird lineages inhabiting different climates. In: Nature Ecology & Evolution. 2018 ; Vol. 2, No. 8. pp. 1258-1267.

Bibtex

@article{f012008988d84b3fa86cd9deee6031d9,
title = "Concordant divergence of mitogenomes and a mitonuclear gene cluster in bird lineages inhabiting different climates",
abstract = "Metabolic processes in eukaryotic cells depend on interactions between mitochondrial and nuclear gene products (mitonuclear interactions). These interactions could have a direct role in population divergence. Here, we study mitonuclear co-evolution in a widespread bird that experienced population divergence followed by bidirectional mitochondrial introgression into different nuclear backgrounds. Using >60,000 single nucleotide polymorphisms, we quantify patterns of nuclear genetic differentiation between populations that occupy areas with different climates and harbour deeply divergent mitochondrial lineages despite ongoing nuclear gene flow. We find that strong genetic differentiation and sequence divergence in a region of ~15.4 mega- bases on chromosome 1A mirror the geographic pattern of mitochondrial DNA divergence. This result is seen in two differ- ent transects representing populations with different nuclear backgrounds. The chromosome 1A region is enriched for genes performing mitochondrial functions (N-mt genes). Molecular signatures of selective sweeps in this region alongside those in the mitochondrial genome suggest a history of adaptive mitonuclear co-introgression. Moreover, evidence for large linkage disequilibrium blocks in this genomic region suggests that low recombination could facilitate functional interactions between co-evolved nuclear alleles. Our results are consistent with mitonuclear co-evolution as an important mechanism for population divergence and local adaptation.",
author = "Morales, {Hern{\'a}n E.} and Alexandra Pavlova and Nevil Amos and Richard Major and Andrzej Kilian and Chris Greening and Paul Sunnucks",
year = "2018",
doi = "10.1038/s41559-018-0606-3",
language = "Udefineret/Ukendt",
volume = "2",
pages = "1258--1267",
journal = "Nature Ecology & Evolution",
issn = "2397-334X",
publisher = "nature publishing group",
number = "8",

}

RIS

TY - JOUR

T1 - Concordant divergence of mitogenomes and a mitonuclear gene cluster in bird lineages inhabiting different climates

AU - Morales, Hernán E.

AU - Pavlova, Alexandra

AU - Amos, Nevil

AU - Major, Richard

AU - Kilian, Andrzej

AU - Greening, Chris

AU - Sunnucks, Paul

PY - 2018

Y1 - 2018

N2 - Metabolic processes in eukaryotic cells depend on interactions between mitochondrial and nuclear gene products (mitonuclear interactions). These interactions could have a direct role in population divergence. Here, we study mitonuclear co-evolution in a widespread bird that experienced population divergence followed by bidirectional mitochondrial introgression into different nuclear backgrounds. Using >60,000 single nucleotide polymorphisms, we quantify patterns of nuclear genetic differentiation between populations that occupy areas with different climates and harbour deeply divergent mitochondrial lineages despite ongoing nuclear gene flow. We find that strong genetic differentiation and sequence divergence in a region of ~15.4 mega- bases on chromosome 1A mirror the geographic pattern of mitochondrial DNA divergence. This result is seen in two differ- ent transects representing populations with different nuclear backgrounds. The chromosome 1A region is enriched for genes performing mitochondrial functions (N-mt genes). Molecular signatures of selective sweeps in this region alongside those in the mitochondrial genome suggest a history of adaptive mitonuclear co-introgression. Moreover, evidence for large linkage disequilibrium blocks in this genomic region suggests that low recombination could facilitate functional interactions between co-evolved nuclear alleles. Our results are consistent with mitonuclear co-evolution as an important mechanism for population divergence and local adaptation.

AB - Metabolic processes in eukaryotic cells depend on interactions between mitochondrial and nuclear gene products (mitonuclear interactions). These interactions could have a direct role in population divergence. Here, we study mitonuclear co-evolution in a widespread bird that experienced population divergence followed by bidirectional mitochondrial introgression into different nuclear backgrounds. Using >60,000 single nucleotide polymorphisms, we quantify patterns of nuclear genetic differentiation between populations that occupy areas with different climates and harbour deeply divergent mitochondrial lineages despite ongoing nuclear gene flow. We find that strong genetic differentiation and sequence divergence in a region of ~15.4 mega- bases on chromosome 1A mirror the geographic pattern of mitochondrial DNA divergence. This result is seen in two differ- ent transects representing populations with different nuclear backgrounds. The chromosome 1A region is enriched for genes performing mitochondrial functions (N-mt genes). Molecular signatures of selective sweeps in this region alongside those in the mitochondrial genome suggest a history of adaptive mitonuclear co-introgression. Moreover, evidence for large linkage disequilibrium blocks in this genomic region suggests that low recombination could facilitate functional interactions between co-evolved nuclear alleles. Our results are consistent with mitonuclear co-evolution as an important mechanism for population divergence and local adaptation.

U2 - 10.1038/s41559-018-0606-3

DO - 10.1038/s41559-018-0606-3

M3 - Tidsskriftartikel

VL - 2

SP - 1258

EP - 1267

JO - Nature Ecology & Evolution

JF - Nature Ecology & Evolution

SN - 2397-334X

IS - 8

ER -

ID: 246093923