Population genomics of grey wolves and wolf-like canids in North America

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Population genomics of grey wolves and wolf-like canids in North America. / Sinding, Mikkel-Holger S.; Gopalakrishan, Shyam; Vieira, Filipe G.; Samaniego Castruita, Jose A.; Raundrup, Katrine; Heide-Jørgensen, Mads Peter; Meldgaard, Morten; Petersen, Bent; Sicheritz-Ponten, Thomas; Mikkelsen, Johan Brus; Marquard-Petersen, Ulf; Dietz, Rune; Sonne, Christian; Dalén, Love; Bachmann, Lutz; Wiig, Øystein; Hansen, Anders J.; Gilbert, M. Thomas P.

In: PLOS Genetics, Vol. 14, No. 11, e1007745, 2018.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Sinding, M-HS, Gopalakrishan, S, Vieira, FG, Samaniego Castruita, JA, Raundrup, K, Heide-Jørgensen, MP, Meldgaard, M, Petersen, B, Sicheritz-Ponten, T, Mikkelsen, JB, Marquard-Petersen, U, Dietz, R, Sonne, C, Dalén, L, Bachmann, L, Wiig, Ø, Hansen, AJ & Gilbert, MTP 2018, 'Population genomics of grey wolves and wolf-like canids in North America', PLOS Genetics, vol. 14, no. 11, e1007745. https://doi.org/10.1371/journal.pgen.1007745

APA

Sinding, M-H. S., Gopalakrishan, S., Vieira, F. G., Samaniego Castruita, J. A., Raundrup, K., Heide-Jørgensen, M. P., Meldgaard, M., Petersen, B., Sicheritz-Ponten, T., Mikkelsen, J. B., Marquard-Petersen, U., Dietz, R., Sonne, C., Dalén, L., Bachmann, L., Wiig, Ø., Hansen, A. J., & Gilbert, M. T. P. (2018). Population genomics of grey wolves and wolf-like canids in North America. PLOS Genetics, 14(11), [e1007745]. https://doi.org/10.1371/journal.pgen.1007745

Vancouver

Sinding M-HS, Gopalakrishan S, Vieira FG, Samaniego Castruita JA, Raundrup K, Heide-Jørgensen MP et al. Population genomics of grey wolves and wolf-like canids in North America. PLOS Genetics. 2018;14(11). e1007745. https://doi.org/10.1371/journal.pgen.1007745

Author

Sinding, Mikkel-Holger S. ; Gopalakrishan, Shyam ; Vieira, Filipe G. ; Samaniego Castruita, Jose A. ; Raundrup, Katrine ; Heide-Jørgensen, Mads Peter ; Meldgaard, Morten ; Petersen, Bent ; Sicheritz-Ponten, Thomas ; Mikkelsen, Johan Brus ; Marquard-Petersen, Ulf ; Dietz, Rune ; Sonne, Christian ; Dalén, Love ; Bachmann, Lutz ; Wiig, Øystein ; Hansen, Anders J. ; Gilbert, M. Thomas P. / Population genomics of grey wolves and wolf-like canids in North America. In: PLOS Genetics. 2018 ; Vol. 14, No. 11.

Bibtex

@article{4d30f4a883d542bbae1fe73aa952fec0,
title = "Population genomics of grey wolves and wolf-like canids in North America",
abstract = "North America is currently home to a number of grey wolf (Canis lupus) and wolf-like canid populations, including the coyote (Canis latrans) and the taxonomically controversial red, Eastern timber and Great Lakes wolves. We explored their population structure and regional gene flow using a dataset of 40 full genome sequences that represent the extant diversity of North American wolves and wolf-like canid populations. This included 15 new genomes (13 North American grey wolves, 1 red wolf and 1 Eastern timber/Great Lakes wolf), ranging from 0.4 to 15x coverage. In addition to providing full genome support for the previously proposed coyote-wolf admixture origin for the taxonomically controversial red, Eastern timber and Great Lakes wolves, the discriminatory power offered by our dataset suggests all North American grey wolves, including the Mexican form, are monophyletic, and thus share a common ancestor to the exclusion of all other wolves. Furthermore, we identify three distinct populations in the high arctic, one being a previously unidentified “Polar wolf” population endemic to Ellesmere Island and Greenland. Genetic diversity analyses reveal particularly high inbreeding and low heterozygosity in these Polar wolves, consistent with long-term isolation from the other North American wolves.",
author = "Sinding, {Mikkel-Holger S.} and Shyam Gopalakrishan and Vieira, {Filipe G.} and {Samaniego Castruita}, {Jose A.} and Katrine Raundrup and Heide-J{\o}rgensen, {Mads Peter} and Morten Meldgaard and Bent Petersen and Thomas Sicheritz-Ponten and Mikkelsen, {Johan Brus} and Ulf Marquard-Petersen and Rune Dietz and Christian Sonne and Love Dal{\'e}n and Lutz Bachmann and {\O}ystein Wiig and Hansen, {Anders J.} and Gilbert, {M. Thomas P.}",
year = "2018",
doi = "10.1371/journal.pgen.1007745",
language = "English",
volume = "14",
journal = "P L o S Genetics",
issn = "1553-7390",
publisher = "Public Library of Science",
number = "11",

}

RIS

TY - JOUR

T1 - Population genomics of grey wolves and wolf-like canids in North America

AU - Sinding, Mikkel-Holger S.

AU - Gopalakrishan, Shyam

AU - Vieira, Filipe G.

AU - Samaniego Castruita, Jose A.

AU - Raundrup, Katrine

AU - Heide-Jørgensen, Mads Peter

AU - Meldgaard, Morten

AU - Petersen, Bent

AU - Sicheritz-Ponten, Thomas

AU - Mikkelsen, Johan Brus

AU - Marquard-Petersen, Ulf

AU - Dietz, Rune

AU - Sonne, Christian

AU - Dalén, Love

AU - Bachmann, Lutz

AU - Wiig, Øystein

AU - Hansen, Anders J.

AU - Gilbert, M. Thomas P.

PY - 2018

Y1 - 2018

N2 - North America is currently home to a number of grey wolf (Canis lupus) and wolf-like canid populations, including the coyote (Canis latrans) and the taxonomically controversial red, Eastern timber and Great Lakes wolves. We explored their population structure and regional gene flow using a dataset of 40 full genome sequences that represent the extant diversity of North American wolves and wolf-like canid populations. This included 15 new genomes (13 North American grey wolves, 1 red wolf and 1 Eastern timber/Great Lakes wolf), ranging from 0.4 to 15x coverage. In addition to providing full genome support for the previously proposed coyote-wolf admixture origin for the taxonomically controversial red, Eastern timber and Great Lakes wolves, the discriminatory power offered by our dataset suggests all North American grey wolves, including the Mexican form, are monophyletic, and thus share a common ancestor to the exclusion of all other wolves. Furthermore, we identify three distinct populations in the high arctic, one being a previously unidentified “Polar wolf” population endemic to Ellesmere Island and Greenland. Genetic diversity analyses reveal particularly high inbreeding and low heterozygosity in these Polar wolves, consistent with long-term isolation from the other North American wolves.

AB - North America is currently home to a number of grey wolf (Canis lupus) and wolf-like canid populations, including the coyote (Canis latrans) and the taxonomically controversial red, Eastern timber and Great Lakes wolves. We explored their population structure and regional gene flow using a dataset of 40 full genome sequences that represent the extant diversity of North American wolves and wolf-like canid populations. This included 15 new genomes (13 North American grey wolves, 1 red wolf and 1 Eastern timber/Great Lakes wolf), ranging from 0.4 to 15x coverage. In addition to providing full genome support for the previously proposed coyote-wolf admixture origin for the taxonomically controversial red, Eastern timber and Great Lakes wolves, the discriminatory power offered by our dataset suggests all North American grey wolves, including the Mexican form, are monophyletic, and thus share a common ancestor to the exclusion of all other wolves. Furthermore, we identify three distinct populations in the high arctic, one being a previously unidentified “Polar wolf” population endemic to Ellesmere Island and Greenland. Genetic diversity analyses reveal particularly high inbreeding and low heterozygosity in these Polar wolves, consistent with long-term isolation from the other North American wolves.

U2 - 10.1371/journal.pgen.1007745

DO - 10.1371/journal.pgen.1007745

M3 - Journal article

C2 - 30419012

VL - 14

JO - P L o S Genetics

JF - P L o S Genetics

SN - 1553-7390

IS - 11

M1 - e1007745

ER -

ID: 227840332