A genomic exploration of the early evolution of extant cats and their sabre-toothed relatives: [version 2; peer review: 2 approved]

Research output: Contribution to journalJournal articlepeer-review

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A genomic exploration of the early evolution of extant cats and their sabre-toothed relatives : [version 2; peer review: 2 approved]. / Westbury, Michael V.; Barnett, Ross; Sandoval-Velasco, Marcela; Gower, Graham; Vieira, Filipe Garrett; de Manuel, Marc; Hansen, Anders J.; Yamaguchi, Nobuyuki; Werdelin, Lars; Marques-Bonet, Tomas; Gilbert, M. Thomas P.; Lorenzen, Eline D.

In: Open Research Europe, Vol. 1, 25, 2021.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Westbury, MV, Barnett, R, Sandoval-Velasco, M, Gower, G, Vieira, FG, de Manuel, M, Hansen, AJ, Yamaguchi, N, Werdelin, L, Marques-Bonet, T, Gilbert, MTP & Lorenzen, ED 2021, 'A genomic exploration of the early evolution of extant cats and their sabre-toothed relatives: [version 2; peer review: 2 approved]', Open Research Europe, vol. 1, 25. https://doi.org/10.12688/openreseurope.13104.2

APA

Westbury, M. V., Barnett, R., Sandoval-Velasco, M., Gower, G., Vieira, F. G., de Manuel, M., Hansen, A. J., Yamaguchi, N., Werdelin, L., Marques-Bonet, T., Gilbert, M. T. P., & Lorenzen, E. D. (2021). A genomic exploration of the early evolution of extant cats and their sabre-toothed relatives: [version 2; peer review: 2 approved]. Open Research Europe, 1, [25]. https://doi.org/10.12688/openreseurope.13104.2

Vancouver

Westbury MV, Barnett R, Sandoval-Velasco M, Gower G, Vieira FG, de Manuel M et al. A genomic exploration of the early evolution of extant cats and their sabre-toothed relatives: [version 2; peer review: 2 approved]. Open Research Europe. 2021;1. 25. https://doi.org/10.12688/openreseurope.13104.2

Author

Westbury, Michael V. ; Barnett, Ross ; Sandoval-Velasco, Marcela ; Gower, Graham ; Vieira, Filipe Garrett ; de Manuel, Marc ; Hansen, Anders J. ; Yamaguchi, Nobuyuki ; Werdelin, Lars ; Marques-Bonet, Tomas ; Gilbert, M. Thomas P. ; Lorenzen, Eline D. / A genomic exploration of the early evolution of extant cats and their sabre-toothed relatives : [version 2; peer review: 2 approved]. In: Open Research Europe. 2021 ; Vol. 1.

Bibtex

@article{7efb0a5c86f448868b5bb3a1b65afef5,
title = "A genomic exploration of the early evolution of extant cats and their sabre-toothed relatives: [version 2; peer review: 2 approved]",
abstract = "Background: The evolutionary relationships of Felidae during their Early-Middle Miocene radiation is contentious. Although the early common ancestors have been subsumed under the grade-group Pseudaelurus, this group is thought to be paraphyletic, including the early ancestors of both modern cats and extinct sabretooths. Methods: Here, we sequenced a draft nuclear genome of Smilodon populator, dated to 13,182 ± 90 cal BP, making this the oldest palaeogenome from South America to date, a region known to be problematic for ancient DNA preservation. We analysed this genome, together with genomes from other extinct and extant cats to investigate their phylogenetic relationships. Results: We confirm a deep divergence (~20.65 Ma) within sabre-toothed cats. Through the analysis of both simulated and empirical data, we show a lack of gene flow between Smilodon and contemporary Felidae. Conclusions: Given that some species traditionally assigned to Pseudaelurus originated in the Early Miocene ~20 Ma, this indicates that some species of Pseudaelurus may be younger than the lineages they purportedly gave rise to, further supporting the hypothesis that Pseudaelurus was paraphyletic.",
keywords = "Ancient DNA, Felidae, Gene flow, Genomics, Palaeogenome, Phylogeny, Smilodon",
author = "Westbury, {Michael V.} and Ross Barnett and Marcela Sandoval-Velasco and Graham Gower and Vieira, {Filipe Garrett} and {de Manuel}, Marc and Hansen, {Anders J.} and Nobuyuki Yamaguchi and Lars Werdelin and Tomas Marques-Bonet and Gilbert, {M. Thomas P.} and Lorenzen, {Eline D.}",
note = "A genomic exploration of the early evolution of extant cats and their sabre-toothed relatives [version 1; peer review: 2 approved] DOI: 10.12688/openreseurope.13104.1",
year = "2021",
doi = "10.12688/openreseurope.13104.2",
language = "English",
volume = "1",
journal = "Open Research Europe",
issn = "2732-5121",
publisher = "F1000Research",

}

RIS

TY - JOUR

T1 - A genomic exploration of the early evolution of extant cats and their sabre-toothed relatives

T2 - [version 2; peer review: 2 approved]

AU - Westbury, Michael V.

AU - Barnett, Ross

AU - Sandoval-Velasco, Marcela

AU - Gower, Graham

AU - Vieira, Filipe Garrett

AU - de Manuel, Marc

AU - Hansen, Anders J.

AU - Yamaguchi, Nobuyuki

AU - Werdelin, Lars

AU - Marques-Bonet, Tomas

AU - Gilbert, M. Thomas P.

AU - Lorenzen, Eline D.

N1 - A genomic exploration of the early evolution of extant cats and their sabre-toothed relatives [version 1; peer review: 2 approved] DOI: 10.12688/openreseurope.13104.1

PY - 2021

Y1 - 2021

N2 - Background: The evolutionary relationships of Felidae during their Early-Middle Miocene radiation is contentious. Although the early common ancestors have been subsumed under the grade-group Pseudaelurus, this group is thought to be paraphyletic, including the early ancestors of both modern cats and extinct sabretooths. Methods: Here, we sequenced a draft nuclear genome of Smilodon populator, dated to 13,182 ± 90 cal BP, making this the oldest palaeogenome from South America to date, a region known to be problematic for ancient DNA preservation. We analysed this genome, together with genomes from other extinct and extant cats to investigate their phylogenetic relationships. Results: We confirm a deep divergence (~20.65 Ma) within sabre-toothed cats. Through the analysis of both simulated and empirical data, we show a lack of gene flow between Smilodon and contemporary Felidae. Conclusions: Given that some species traditionally assigned to Pseudaelurus originated in the Early Miocene ~20 Ma, this indicates that some species of Pseudaelurus may be younger than the lineages they purportedly gave rise to, further supporting the hypothesis that Pseudaelurus was paraphyletic.

AB - Background: The evolutionary relationships of Felidae during their Early-Middle Miocene radiation is contentious. Although the early common ancestors have been subsumed under the grade-group Pseudaelurus, this group is thought to be paraphyletic, including the early ancestors of both modern cats and extinct sabretooths. Methods: Here, we sequenced a draft nuclear genome of Smilodon populator, dated to 13,182 ± 90 cal BP, making this the oldest palaeogenome from South America to date, a region known to be problematic for ancient DNA preservation. We analysed this genome, together with genomes from other extinct and extant cats to investigate their phylogenetic relationships. Results: We confirm a deep divergence (~20.65 Ma) within sabre-toothed cats. Through the analysis of both simulated and empirical data, we show a lack of gene flow between Smilodon and contemporary Felidae. Conclusions: Given that some species traditionally assigned to Pseudaelurus originated in the Early Miocene ~20 Ma, this indicates that some species of Pseudaelurus may be younger than the lineages they purportedly gave rise to, further supporting the hypothesis that Pseudaelurus was paraphyletic.

KW - Ancient DNA

KW - Felidae

KW - Gene flow

KW - Genomics

KW - Palaeogenome

KW - Phylogeny

KW - Smilodon

U2 - 10.12688/openreseurope.13104.2

DO - 10.12688/openreseurope.13104.2

M3 - Journal article

C2 - 35098251

AN - SCOPUS:85107704729

VL - 1

JO - Open Research Europe

JF - Open Research Europe

SN - 2732-5121

M1 - 25

ER -

ID: 272249609