Authentication and assessment of contamination in ancient DNA

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Standard

Authentication and assessment of contamination in ancient DNA. / Renaud, Gabriel; Schubert, Mikkel; Sawyer, Susanna; Orlando, Ludovic.

Ancient DNA: Methods and Protocols. ed. / Beth Shapiro; Axel Barlow; Peter D. Heintzman; Michael Hofreiter; Johanna L. A. Paijmans; André E. R. Soares. 2. ed. ed. Humana Press, 2019. p. 163-194 (Methods in Molecular Biology, Vol. 1963).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Harvard

Renaud, G, Schubert, M, Sawyer, S & Orlando, L 2019, Authentication and assessment of contamination in ancient DNA. in B Shapiro, A Barlow, PD Heintzman, M Hofreiter, JLA Paijmans & AER Soares (eds), Ancient DNA: Methods and Protocols. 2. ed. edn, Humana Press, Methods in Molecular Biology, vol. 1963, pp. 163-194. https://doi.org/10.1007/978-1-4939-9176-1_17

APA

Renaud, G., Schubert, M., Sawyer, S., & Orlando, L. (2019). Authentication and assessment of contamination in ancient DNA. In B. Shapiro, A. Barlow, P. D. Heintzman, M. Hofreiter, J. L. A. Paijmans, & A. E. R. Soares (Eds.), Ancient DNA: Methods and Protocols (2. ed. ed., pp. 163-194). Humana Press. Methods in Molecular Biology Vol. 1963 https://doi.org/10.1007/978-1-4939-9176-1_17

Vancouver

Renaud G, Schubert M, Sawyer S, Orlando L. Authentication and assessment of contamination in ancient DNA. In Shapiro B, Barlow A, Heintzman PD, Hofreiter M, Paijmans JLA, Soares AER, editors, Ancient DNA: Methods and Protocols. 2. ed. ed. Humana Press. 2019. p. 163-194. (Methods in Molecular Biology, Vol. 1963). https://doi.org/10.1007/978-1-4939-9176-1_17

Author

Renaud, Gabriel ; Schubert, Mikkel ; Sawyer, Susanna ; Orlando, Ludovic. / Authentication and assessment of contamination in ancient DNA. Ancient DNA: Methods and Protocols. editor / Beth Shapiro ; Axel Barlow ; Peter D. Heintzman ; Michael Hofreiter ; Johanna L. A. Paijmans ; André E. R. Soares. 2. ed. ed. Humana Press, 2019. pp. 163-194 (Methods in Molecular Biology, Vol. 1963).

Bibtex

@inbook{bd473e7dde9c4a7e965535ed64a45372,
title = "Authentication and assessment of contamination in ancient DNA",
abstract = "Contamination from both present-day humans and postmortem microbial sources is a common challenge in ancient DNA studies. Here we present a suite of tools to assist in the assessment of contamination in ancient DNA data sets. These tools perform standard tests of authenticity of ancient DNA data including detecting the presence of postmortem damage signatures in sequence alignments and quantifying the amount of present-day human contamination.",
keywords = "Ancient DNA, Contamination, DICE, mapDamage2.0, Postmortem damage, Schmutzi",
author = "Gabriel Renaud and Mikkel Schubert and Susanna Sawyer and Ludovic Orlando",
year = "2019",
doi = "10.1007/978-1-4939-9176-1_17",
language = "English",
isbn = " 978-1-4939-9175-4",
series = "Methods in Molecular Biology",
publisher = "Humana Press",
pages = "163--194",
editor = "Beth Shapiro and Axel Barlow and Heintzman, {Peter D.} and Michael Hofreiter and Paijmans, {Johanna L. A.} and Soares, {Andr{\'e} E. R.}",
booktitle = "Ancient DNA",
address = "United States",
edition = "2. ed.",

}

RIS

TY - CHAP

T1 - Authentication and assessment of contamination in ancient DNA

AU - Renaud, Gabriel

AU - Schubert, Mikkel

AU - Sawyer, Susanna

AU - Orlando, Ludovic

PY - 2019

Y1 - 2019

N2 - Contamination from both present-day humans and postmortem microbial sources is a common challenge in ancient DNA studies. Here we present a suite of tools to assist in the assessment of contamination in ancient DNA data sets. These tools perform standard tests of authenticity of ancient DNA data including detecting the presence of postmortem damage signatures in sequence alignments and quantifying the amount of present-day human contamination.

AB - Contamination from both present-day humans and postmortem microbial sources is a common challenge in ancient DNA studies. Here we present a suite of tools to assist in the assessment of contamination in ancient DNA data sets. These tools perform standard tests of authenticity of ancient DNA data including detecting the presence of postmortem damage signatures in sequence alignments and quantifying the amount of present-day human contamination.

KW - Ancient DNA

KW - Contamination

KW - DICE

KW - mapDamage2.0

KW - Postmortem damage

KW - Schmutzi

U2 - 10.1007/978-1-4939-9176-1_17

DO - 10.1007/978-1-4939-9176-1_17

M3 - Book chapter

C2 - 30875054

AN - SCOPUS:85063003614

SN - 978-1-4939-9175-4

T3 - Methods in Molecular Biology

SP - 163

EP - 194

BT - Ancient DNA

A2 - Shapiro, Beth

A2 - Barlow, Axel

A2 - Heintzman, Peter D.

A2 - Hofreiter, Michael

A2 - Paijmans, Johanna L. A.

A2 - Soares, André E. R.

PB - Humana Press

ER -

ID: 227047899