Comparative genomics provides insights into the aquatic adaptations of mammals

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Comparative genomics provides insights into the aquatic adaptations of mammals. / Yuan, Yuan; Zhang, Yaolei; Zhang, Peijun; Liu, Chang; Wang, Jiahao; Gao, Haiyu; Rus Hoelzel, A.; Seim, Inge; Lv, Meiqi; Lin, Mingli; Dong, Lijun; Gao, Haoyang; Yang, Zixin; Caruso, Francesco; Lin, Wenzhi; Da Fonseca, Rute R.; Wang, Ding; Wang, Xianyan; Rasmussen, Marianne H.; Liu, Mingming; Zheng, Jinsong; Zhao, Liyuan; Campos, Paula F.; Kang, Hui; Iversen, Maria; Song, Yue; Guo, Xinyu; Guo, Jiao; Qin, Yating; Pan, Shanshan; Xu, Qiwu; Meng, Lingfeng; A, Yunga; Liu, Shanshan; Ming-Yuen Lee, Simon; Liu, Xin; Xu, Xun; Yang, Huanming; Fan, Guangyi; Wang, Kun; Li, Songhai.

In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, No. 37, e2106080118, 2021.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Yuan, Y, Zhang, Y, Zhang, P, Liu, C, Wang, J, Gao, H, Rus Hoelzel, A, Seim, I, Lv, M, Lin, M, Dong, L, Gao, H, Yang, Z, Caruso, F, Lin, W, Da Fonseca, RR, Wang, D, Wang, X, Rasmussen, MH, Liu, M, Zheng, J, Zhao, L, Campos, PF, Kang, H, Iversen, M, Song, Y, Guo, X, Guo, J, Qin, Y, Pan, S, Xu, Q, Meng, L, A, Y, Liu, S, Ming-Yuen Lee, S, Liu, X, Xu, X, Yang, H, Fan, G, Wang, K & Li, S 2021, 'Comparative genomics provides insights into the aquatic adaptations of mammals', Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 37, e2106080118. https://doi.org/10.1073/pnas.2106080118

APA

Yuan, Y., Zhang, Y., Zhang, P., Liu, C., Wang, J., Gao, H., Rus Hoelzel, A., Seim, I., Lv, M., Lin, M., Dong, L., Gao, H., Yang, Z., Caruso, F., Lin, W., Da Fonseca, R. R., Wang, D., Wang, X., Rasmussen, M. H., ... Li, S. (2021). Comparative genomics provides insights into the aquatic adaptations of mammals. Proceedings of the National Academy of Sciences of the United States of America, 118(37), [e2106080118]. https://doi.org/10.1073/pnas.2106080118

Vancouver

Yuan Y, Zhang Y, Zhang P, Liu C, Wang J, Gao H et al. Comparative genomics provides insights into the aquatic adaptations of mammals. Proceedings of the National Academy of Sciences of the United States of America. 2021;118(37). e2106080118. https://doi.org/10.1073/pnas.2106080118

Author

Yuan, Yuan ; Zhang, Yaolei ; Zhang, Peijun ; Liu, Chang ; Wang, Jiahao ; Gao, Haiyu ; Rus Hoelzel, A. ; Seim, Inge ; Lv, Meiqi ; Lin, Mingli ; Dong, Lijun ; Gao, Haoyang ; Yang, Zixin ; Caruso, Francesco ; Lin, Wenzhi ; Da Fonseca, Rute R. ; Wang, Ding ; Wang, Xianyan ; Rasmussen, Marianne H. ; Liu, Mingming ; Zheng, Jinsong ; Zhao, Liyuan ; Campos, Paula F. ; Kang, Hui ; Iversen, Maria ; Song, Yue ; Guo, Xinyu ; Guo, Jiao ; Qin, Yating ; Pan, Shanshan ; Xu, Qiwu ; Meng, Lingfeng ; A, Yunga ; Liu, Shanshan ; Ming-Yuen Lee, Simon ; Liu, Xin ; Xu, Xun ; Yang, Huanming ; Fan, Guangyi ; Wang, Kun ; Li, Songhai. / Comparative genomics provides insights into the aquatic adaptations of mammals. In: Proceedings of the National Academy of Sciences of the United States of America. 2021 ; Vol. 118, No. 37.

Bibtex

@article{8389746e1c85487c98a713e0d9ffe2cd,

title = "Comparative genomics provides insights into the aquatic adaptations of mammals",

abstract = "The ancestors of marine mammals once roamed the land and independently committed to an aquatic lifestyle. These macroevolutionary transitions have intrigued scientists for centuries. Here, we generated high-quality genome assemblies of 17 marine mammals (11 cetaceans and six pinnipeds), including eight assemblies at the chromosome level. Incorporating previously published data, we reconstructed the marine mammal phylogeny and population histories and identified numerous idiosyncratic and convergent genomic variations that possibly contributed to the transition from land to water in marine mammal lineages. Genes associated with the formation of blubber (NFIA), vascular development (SEMA3E), and heat production by brown adipose tissue (UCP1) had unique changes that may contribute to marine mammal thermoregulation. We also observed many lineage-specific changes in the marine mammals, including genes associated with deep diving and navigation. Our study advances understanding of the timing, pattern, and molecular changes associated with the evolution of mammalian lineages adapting to aquatic life.",

keywords = "Aquatic adaptation, Comparative genomics, Marine mammals",

author = "Yuan Yuan and Yaolei Zhang and Peijun Zhang and Chang Liu and Jiahao Wang and Haiyu Gao and {Rus Hoelzel}, A. and Inge Seim and Meiqi Lv and Mingli Lin and Lijun Dong and Haoyang Gao and Zixin Yang and Francesco Caruso and Wenzhi Lin and {Da Fonseca}, {Rute R.} and Ding Wang and Xianyan Wang and Rasmussen, {Marianne H.} and Mingming Liu and Jinsong Zheng and Liyuan Zhao and Campos, {Paula F.} and Hui Kang and Maria Iversen and Yue Song and Xinyu Guo and Jiao Guo and Yating Qin and Shanshan Pan and Qiwu Xu and Lingfeng Meng and Yunga A and Shanshan Liu and {Ming-Yuen Lee}, Simon and Xin Liu and Xun Xu and Huanming Yang and Guangyi Fan and Kun Wang and Songhai Li",

year = "2021",

doi = "10.1073/pnas.2106080118",

language = "English",

volume = "118",

journal = "Proceedings of the National Academy of Sciences of the United States of America",

issn = "0027-8424",

publisher = "The National Academy of Sciences of the United States of America",

number = "37",

}

RIS

TY - JOUR

T1 - Comparative genomics provides insights into the aquatic adaptations of mammals

AU - Yuan, Yuan

AU - Zhang, Yaolei

AU - Zhang, Peijun

AU - Liu, Chang

AU - Wang, Jiahao

AU - Gao, Haiyu

AU - Rus Hoelzel, A.

AU - Seim, Inge

AU - Lv, Meiqi

AU - Lin, Mingli

AU - Dong, Lijun

AU - Gao, Haoyang

AU - Yang, Zixin

AU - Caruso, Francesco

AU - Lin, Wenzhi

AU - Da Fonseca, Rute R.

AU - Wang, Ding

AU - Wang, Xianyan

AU - Rasmussen, Marianne H.

AU - Liu, Mingming

AU - Zheng, Jinsong

AU - Zhao, Liyuan

AU - Campos, Paula F.

AU - Kang, Hui

AU - Iversen, Maria

AU - Song, Yue

AU - Guo, Xinyu

AU - Guo, Jiao

AU - Qin, Yating

AU - Pan, Shanshan

AU - Xu, Qiwu

AU - Meng, Lingfeng

AU - A, Yunga

AU - Liu, Shanshan

AU - Ming-Yuen Lee, Simon

AU - Liu, Xin

AU - Xu, Xun

AU - Yang, Huanming

AU - Fan, Guangyi

AU - Wang, Kun

AU - Li, Songhai

PY - 2021

Y1 - 2021

N2 - The ancestors of marine mammals once roamed the land and independently committed to an aquatic lifestyle. These macroevolutionary transitions have intrigued scientists for centuries. Here, we generated high-quality genome assemblies of 17 marine mammals (11 cetaceans and six pinnipeds), including eight assemblies at the chromosome level. Incorporating previously published data, we reconstructed the marine mammal phylogeny and population histories and identified numerous idiosyncratic and convergent genomic variations that possibly contributed to the transition from land to water in marine mammal lineages. Genes associated with the formation of blubber (NFIA), vascular development (SEMA3E), and heat production by brown adipose tissue (UCP1) had unique changes that may contribute to marine mammal thermoregulation. We also observed many lineage-specific changes in the marine mammals, including genes associated with deep diving and navigation. Our study advances understanding of the timing, pattern, and molecular changes associated with the evolution of mammalian lineages adapting to aquatic life.

AB - The ancestors of marine mammals once roamed the land and independently committed to an aquatic lifestyle. These macroevolutionary transitions have intrigued scientists for centuries. Here, we generated high-quality genome assemblies of 17 marine mammals (11 cetaceans and six pinnipeds), including eight assemblies at the chromosome level. Incorporating previously published data, we reconstructed the marine mammal phylogeny and population histories and identified numerous idiosyncratic and convergent genomic variations that possibly contributed to the transition from land to water in marine mammal lineages. Genes associated with the formation of blubber (NFIA), vascular development (SEMA3E), and heat production by brown adipose tissue (UCP1) had unique changes that may contribute to marine mammal thermoregulation. We also observed many lineage-specific changes in the marine mammals, including genes associated with deep diving and navigation. Our study advances understanding of the timing, pattern, and molecular changes associated with the evolution of mammalian lineages adapting to aquatic life.

KW - Aquatic adaptation

KW - Comparative genomics

KW - Marine mammals

U2 - 10.1073/pnas.2106080118

DO - 10.1073/pnas.2106080118

M3 - Journal article

C2 - 34503999

AN - SCOPUS:85114743612

VL - 118

JO - Proceedings of the National Academy of Sciences of the United States of America

JF - Proceedings of the National Academy of Sciences of the United States of America

SN - 0027-8424

IS - 37

M1 - e2106080118

ER -

ID: 280891313

Globe Institute