Early Pleistocene origin and extensive intra-species diversity of the extinct cave lion

Research output: Contribution to journal › Journal article › Research › peer-review

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Early Pleistocene origin and extensive intra-species diversity of the extinct cave lion. / Stanton, David W. G.; Alberti, Federica; Plotnikov, Valery; Androsov, Semyon; Grigoriev, Semyon; Fedorov, Sergey; Kosintsev, Pavel; Nagel, Doris; Vartanyan, Sergey; Barnes, Ian; Barnett, Ross; Ersmark, Erik; Doeppes, Doris; Germonpre, Mietje; Hofreiter, Michael; Rosendahl, Wilfried; Skoglund, Pontus; Dalen, Love.

In: Scientific Reports, Vol. 10, No. 1, 12621, 2020.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Stanton, DWG, Alberti, F, Plotnikov, V, Androsov, S, Grigoriev, S, Fedorov, S, Kosintsev, P, Nagel, D, Vartanyan, S, Barnes, I, Barnett, R, Ersmark, E, Doeppes, D, Germonpre, M, Hofreiter, M, Rosendahl, W, Skoglund, P & Dalen, L 2020, 'Early Pleistocene origin and extensive intra-species diversity of the extinct cave lion', Scientific Reports, vol. 10, no. 1, 12621. https://doi.org/10.1038/s41598-020-69474-1

APA

Stanton, D. W. G., Alberti, F., Plotnikov, V., Androsov, S., Grigoriev, S., Fedorov, S., Kosintsev, P., Nagel, D., Vartanyan, S., Barnes, I., Barnett, R., Ersmark, E., Doeppes, D., Germonpre, M., Hofreiter, M., Rosendahl, W., Skoglund, P., & Dalen, L. (2020). Early Pleistocene origin and extensive intra-species diversity of the extinct cave lion. Scientific Reports, 10(1), [12621]. https://doi.org/10.1038/s41598-020-69474-1

Vancouver

Stanton DWG, Alberti F, Plotnikov V, Androsov S, Grigoriev S, Fedorov S et al. Early Pleistocene origin and extensive intra-species diversity of the extinct cave lion. Scientific Reports. 2020;10(1). 12621. https://doi.org/10.1038/s41598-020-69474-1

Author

Stanton, David W. G. ; Alberti, Federica ; Plotnikov, Valery ; Androsov, Semyon ; Grigoriev, Semyon ; Fedorov, Sergey ; Kosintsev, Pavel ; Nagel, Doris ; Vartanyan, Sergey ; Barnes, Ian ; Barnett, Ross ; Ersmark, Erik ; Doeppes, Doris ; Germonpre, Mietje ; Hofreiter, Michael ; Rosendahl, Wilfried ; Skoglund, Pontus ; Dalen, Love. / Early Pleistocene origin and extensive intra-species diversity of the extinct cave lion. In: Scientific Reports. 2020 ; Vol. 10, No. 1.

Bibtex

@article{36d3263f245d48519f1799e53707ab42,
title = "Early Pleistocene origin and extensive intra-species diversity of the extinct cave lion",
abstract = "The cave lion is an extinct felid that was widespread across the Holarctic throughout the Late Pleistocene. Its closest extant relative is the lion (Panthera leo), but the timing of the divergence between these two taxa, as well as their taxonomic ranking are contentious. In this study we analyse 31 mitochondrial genome sequences from cave lion individuals that, through a combination of C-14 and genetic tip dating, are estimated to be from dates extending well into the mid-Pleistocene. We identified two deeply diverged and well-supported reciprocally monophyletic mitogenome clades in the cave lion, and an additional third distinct lineage represented by a single individual. One of these clades was restricted to Beringia while the other was prevalent across western Eurasia. These observed clade distributions are in line with previous observations that Beringian and European cave lions were morphologically distinct. The divergence dates for these lineages are estimated to be far older than those between extant lions subspecies. By combining our radiocarbon tip-dates with a split time prior that takes into account the most up-to-date fossil stem calibrations, we estimated the mitochondrial DNA divergence between cave lions and lions to be 1.85 Million ya (95% 0.52- 2.91 Mya). Taken together, these results support previous hypotheses that cave lions existed as at least two subspecies during the Pleistocene, and that lions and cave lions were distinct species.",
keywords = "DNA LIBRARY PREPARATION, GENOME SEQUENCE, ANCIENT",
author = "Stanton, {David W. G.} and Federica Alberti and Valery Plotnikov and Semyon Androsov and Semyon Grigoriev and Sergey Fedorov and Pavel Kosintsev and Doris Nagel and Sergey Vartanyan and Ian Barnes and Ross Barnett and Erik Ersmark and Doris Doeppes and Mietje Germonpre and Michael Hofreiter and Wilfried Rosendahl and Pontus Skoglund and Love Dalen",
year = "2020",
doi = "10.1038/s41598-020-69474-1",
language = "English",
volume = "10",
journal = "Scientific Reports",
issn = "2045-2322",
publisher = "nature publishing group",
number = "1",

}

RIS

TY - JOUR

T1 - Early Pleistocene origin and extensive intra-species diversity of the extinct cave lion

AU - Stanton, David W. G.

AU - Alberti, Federica

AU - Plotnikov, Valery

AU - Androsov, Semyon

AU - Grigoriev, Semyon

AU - Fedorov, Sergey

AU - Kosintsev, Pavel

AU - Nagel, Doris

AU - Vartanyan, Sergey

AU - Barnes, Ian

AU - Barnett, Ross

AU - Ersmark, Erik

AU - Doeppes, Doris

AU - Germonpre, Mietje

AU - Hofreiter, Michael

AU - Rosendahl, Wilfried

AU - Skoglund, Pontus

AU - Dalen, Love

PY - 2020

Y1 - 2020

N2 - The cave lion is an extinct felid that was widespread across the Holarctic throughout the Late Pleistocene. Its closest extant relative is the lion (Panthera leo), but the timing of the divergence between these two taxa, as well as their taxonomic ranking are contentious. In this study we analyse 31 mitochondrial genome sequences from cave lion individuals that, through a combination of C-14 and genetic tip dating, are estimated to be from dates extending well into the mid-Pleistocene. We identified two deeply diverged and well-supported reciprocally monophyletic mitogenome clades in the cave lion, and an additional third distinct lineage represented by a single individual. One of these clades was restricted to Beringia while the other was prevalent across western Eurasia. These observed clade distributions are in line with previous observations that Beringian and European cave lions were morphologically distinct. The divergence dates for these lineages are estimated to be far older than those between extant lions subspecies. By combining our radiocarbon tip-dates with a split time prior that takes into account the most up-to-date fossil stem calibrations, we estimated the mitochondrial DNA divergence between cave lions and lions to be 1.85 Million ya (95% 0.52- 2.91 Mya). Taken together, these results support previous hypotheses that cave lions existed as at least two subspecies during the Pleistocene, and that lions and cave lions were distinct species.

AB - The cave lion is an extinct felid that was widespread across the Holarctic throughout the Late Pleistocene. Its closest extant relative is the lion (Panthera leo), but the timing of the divergence between these two taxa, as well as their taxonomic ranking are contentious. In this study we analyse 31 mitochondrial genome sequences from cave lion individuals that, through a combination of C-14 and genetic tip dating, are estimated to be from dates extending well into the mid-Pleistocene. We identified two deeply diverged and well-supported reciprocally monophyletic mitogenome clades in the cave lion, and an additional third distinct lineage represented by a single individual. One of these clades was restricted to Beringia while the other was prevalent across western Eurasia. These observed clade distributions are in line with previous observations that Beringian and European cave lions were morphologically distinct. The divergence dates for these lineages are estimated to be far older than those between extant lions subspecies. By combining our radiocarbon tip-dates with a split time prior that takes into account the most up-to-date fossil stem calibrations, we estimated the mitochondrial DNA divergence between cave lions and lions to be 1.85 Million ya (95% 0.52- 2.91 Mya). Taken together, these results support previous hypotheses that cave lions existed as at least two subspecies during the Pleistocene, and that lions and cave lions were distinct species.

KW - DNA LIBRARY PREPARATION

KW - GENOME SEQUENCE

KW - ANCIENT

U2 - 10.1038/s41598-020-69474-1

DO - 10.1038/s41598-020-69474-1

M3 - Journal article

C2 - 32724178

VL - 10

JO - Scientific Reports

JF - Scientific Reports

SN - 2045-2322

IS - 1

M1 - 12621

ER -

ID: 248895569