How chromosomal inversions reorient the evolutionary process

Research output: Contribution to journal › Review › Research › peer-review

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How chromosomal inversions reorient the evolutionary process. / Berdan, Emma L.; Barton, Nicholas H.; Butlin, Roger; Charlesworth, Brian; Faria, Rui; Fragata, Inês; Gilbert, Kimberly J.; Jay, Paul; Kapun, Martin; Lotterhos, Katie E.; Mérot, Claire; Durmaz Mitchell, Esra; Pascual, Marta; Peichel, Catherine L.; Rafajlović, Marina; Westram, Anja M.; Schaeffer, Stephen W.; Johannesson, Kerstin; Flatt, Thomas.

In: Journal of Evolutionary Biology, Vol. 36, No. 12, 2023, p. 1761-1782.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Berdan, EL, Barton, NH, Butlin, R, Charlesworth, B, Faria, R, Fragata, I, Gilbert, KJ, Jay, P, Kapun, M, Lotterhos, KE, Mérot, C, Durmaz Mitchell, E, Pascual, M, Peichel, CL, Rafajlović, M, Westram, AM, Schaeffer, SW, Johannesson, K & Flatt, T 2023, 'How chromosomal inversions reorient the evolutionary process', Journal of Evolutionary Biology, vol. 36, no. 12, pp. 1761-1782. https://doi.org/10.1111/jeb.14242

APA

Berdan, E. L., Barton, N. H., Butlin, R., Charlesworth, B., Faria, R., Fragata, I., Gilbert, K. J., Jay, P., Kapun, M., Lotterhos, K. E., Mérot, C., Durmaz Mitchell, E., Pascual, M., Peichel, C. L., Rafajlović, M., Westram, A. M., Schaeffer, S. W., Johannesson, K., & Flatt, T. (2023). How chromosomal inversions reorient the evolutionary process. Journal of Evolutionary Biology, 36(12), 1761-1782. https://doi.org/10.1111/jeb.14242

Vancouver

Berdan EL, Barton NH, Butlin R, Charlesworth B, Faria R, Fragata I et al. How chromosomal inversions reorient the evolutionary process. Journal of Evolutionary Biology. 2023;36(12):1761-1782. https://doi.org/10.1111/jeb.14242

Author

Berdan, Emma L. ; Barton, Nicholas H. ; Butlin, Roger ; Charlesworth, Brian ; Faria, Rui ; Fragata, Inês ; Gilbert, Kimberly J. ; Jay, Paul ; Kapun, Martin ; Lotterhos, Katie E. ; Mérot, Claire ; Durmaz Mitchell, Esra ; Pascual, Marta ; Peichel, Catherine L. ; Rafajlović, Marina ; Westram, Anja M. ; Schaeffer, Stephen W. ; Johannesson, Kerstin ; Flatt, Thomas. / How chromosomal inversions reorient the evolutionary process. In: Journal of Evolutionary Biology. 2023 ; Vol. 36, No. 12. pp. 1761-1782.

Bibtex

@article{433cbe2c88754e9cb92776295aac8112,

title = "How chromosomal inversions reorient the evolutionary process",

abstract = "Inversions are structural mutations that reverse the sequence of a chromosome segment and reduce the effective rate of recombination in the heterozygous state. They play a major role in adaptation, as well as in other evolutionary processes such as speciation. Although inversions have been studied since the 1920s, they remain difficult to investigate because the reduced recombination conferred by them strengthens the effects of drift and hitchhiking, which in turn can obscure signatures of selection. Nonetheless, numerous inversions have been found to be under selection. Given recent advances in population genetic theory and empirical study, here we review how different mechanisms of selection affect the evolution of inversions. A key difference between inversions and other mutations, such as single nucleotide variants, is that the fitness of an inversion may be affected by a larger number of frequently interacting processes. This considerably complicates the analysis of the causes underlying the evolution of inversions. We discuss the extent to which these mechanisms can be disentangled, and by which approach.",

keywords = "adaptation, balanced polymorphisms, chromosomal rearrangements, inversions, linkage, neutrality, recombination, selection",

author = "Berdan, {Emma L.} and Barton, {Nicholas H.} and Roger Butlin and Brian Charlesworth and Rui Faria and In{\^e}s Fragata and Gilbert, {Kimberly J.} and Paul Jay and Martin Kapun and Lotterhos, {Katie E.} and Claire M{\'e}rot and Esra Durmaz Mitchell and Marta Pascual and Peichel, {Catherine L.} and Marina Rafajlovi{\'c} and Westram, {Anja M.} and Schaeffer, {Stephen W.} and Kerstin Johannesson and Thomas Flatt",

note = "Publisher Copyright: {\textcopyright} 2023 The Authors. Journal of Evolutionary Biology published by John Wiley & Sons Ltd on behalf of European Society for Evolutionary Biology.",

year = "2023",

doi = "10.1111/jeb.14242",

language = "English",

volume = "36",

pages = "1761--1782",

journal = "Journal of Evolutionary Biology",

issn = "1010-061X",

publisher = "Wiley-Blackwell",

number = "12",

}

RIS

TY - JOUR

T1 - How chromosomal inversions reorient the evolutionary process

AU - Berdan, Emma L.

AU - Barton, Nicholas H.

AU - Butlin, Roger

AU - Charlesworth, Brian

AU - Faria, Rui

AU - Fragata, Inês

AU - Gilbert, Kimberly J.

AU - Jay, Paul

AU - Kapun, Martin

AU - Lotterhos, Katie E.

AU - Mérot, Claire

AU - Durmaz Mitchell, Esra

AU - Pascual, Marta

AU - Peichel, Catherine L.

AU - Rafajlović, Marina

AU - Westram, Anja M.

AU - Schaeffer, Stephen W.

AU - Johannesson, Kerstin

AU - Flatt, Thomas

PY - 2023

Y1 - 2023

N2 - Inversions are structural mutations that reverse the sequence of a chromosome segment and reduce the effective rate of recombination in the heterozygous state. They play a major role in adaptation, as well as in other evolutionary processes such as speciation. Although inversions have been studied since the 1920s, they remain difficult to investigate because the reduced recombination conferred by them strengthens the effects of drift and hitchhiking, which in turn can obscure signatures of selection. Nonetheless, numerous inversions have been found to be under selection. Given recent advances in population genetic theory and empirical study, here we review how different mechanisms of selection affect the evolution of inversions. A key difference between inversions and other mutations, such as single nucleotide variants, is that the fitness of an inversion may be affected by a larger number of frequently interacting processes. This considerably complicates the analysis of the causes underlying the evolution of inversions. We discuss the extent to which these mechanisms can be disentangled, and by which approach.

AB - Inversions are structural mutations that reverse the sequence of a chromosome segment and reduce the effective rate of recombination in the heterozygous state. They play a major role in adaptation, as well as in other evolutionary processes such as speciation. Although inversions have been studied since the 1920s, they remain difficult to investigate because the reduced recombination conferred by them strengthens the effects of drift and hitchhiking, which in turn can obscure signatures of selection. Nonetheless, numerous inversions have been found to be under selection. Given recent advances in population genetic theory and empirical study, here we review how different mechanisms of selection affect the evolution of inversions. A key difference between inversions and other mutations, such as single nucleotide variants, is that the fitness of an inversion may be affected by a larger number of frequently interacting processes. This considerably complicates the analysis of the causes underlying the evolution of inversions. We discuss the extent to which these mechanisms can be disentangled, and by which approach.

KW - adaptation

KW - balanced polymorphisms

KW - chromosomal rearrangements

KW - inversions

KW - linkage

KW - neutrality

KW - recombination

KW - selection

U2 - 10.1111/jeb.14242

DO - 10.1111/jeb.14242

M3 - Review

C2 - 37942504

AN - SCOPUS:85176211047

VL - 36

SP - 1761

EP - 1782

JO - Journal of Evolutionary Biology

JF - Journal of Evolutionary Biology

SN - 1010-061X

IS - 12

ER -

ID: 373789030

Globe Institute