Paleogenomic insights into the red complex bacteria Tannerella forsythia in Pre-Hispanic and Colonial individuals from Mexico

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Paleogenomic insights into the red complex bacteria Tannerella forsythia in Pre-Hispanic and Colonial individuals from Mexico. / Bravo-Lopez, Miriam; Villa-Islas, Viridiana; Rocha Arriaga, Carolina; Villasenor-Altamirano, Ana B.; Guzman-Solis, Axel; Sandoval-Velasco, Marcela; Wesp, Julie K.; Alcantara, Keitlyn; Lopez-Corral, Aurelio; Gomez-Valdes, Jorge; Mejia, Elizabeth; Herrera, Alberto; Meraz-Moreno, Alejandro; Moreno-Cabrera, Maria de la Luz; Moreno-Estrada, Andres; Nieves-Colon, Maria A.; Olvera, Joel; Perez-Perez, Julia; Iversen, Katrine Hojholt; Rasmussen, Simon; Sandoval, Karla; Zepeda, Gabriela; Avila-Arcos, Maria C.

In: Philosophical Transactions of the Royal Society B: Biological Sciences, Vol. 375, No. 1812, 20190580, 2020.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Bravo-Lopez, M, Villa-Islas, V, Rocha Arriaga, C, Villasenor-Altamirano, AB, Guzman-Solis, A, Sandoval-Velasco, M, Wesp, JK, Alcantara, K, Lopez-Corral, A, Gomez-Valdes, J, Mejia, E, Herrera, A, Meraz-Moreno, A, Moreno-Cabrera, MDLL, Moreno-Estrada, A, Nieves-Colon, MA, Olvera, J, Perez-Perez, J, Iversen, KH, Rasmussen, S, Sandoval, K, Zepeda, G & Avila-Arcos, MC 2020, 'Paleogenomic insights into the red complex bacteria Tannerella forsythia in Pre-Hispanic and Colonial individuals from Mexico', Philosophical Transactions of the Royal Society B: Biological Sciences, vol. 375, no. 1812, 20190580. https://doi.org/10.1098/rstb.2019.0580

APA

Bravo-Lopez, M., Villa-Islas, V., Rocha Arriaga, C., Villasenor-Altamirano, A. B., Guzman-Solis, A., Sandoval-Velasco, M., Wesp, J. K., Alcantara, K., Lopez-Corral, A., Gomez-Valdes, J., Mejia, E., Herrera, A., Meraz-Moreno, A., Moreno-Cabrera, M. D. L. L., Moreno-Estrada, A., Nieves-Colon, M. A., Olvera, J., Perez-Perez, J., Iversen, K. H., ... Avila-Arcos, M. C. (2020). Paleogenomic insights into the red complex bacteria Tannerella forsythia in Pre-Hispanic and Colonial individuals from Mexico. Philosophical Transactions of the Royal Society B: Biological Sciences, 375(1812), [20190580]. https://doi.org/10.1098/rstb.2019.0580

Vancouver

Bravo-Lopez M, Villa-Islas V, Rocha Arriaga C, Villasenor-Altamirano AB, Guzman-Solis A, Sandoval-Velasco M et al. Paleogenomic insights into the red complex bacteria Tannerella forsythia in Pre-Hispanic and Colonial individuals from Mexico. Philosophical Transactions of the Royal Society B: Biological Sciences. 2020;375(1812). 20190580. https://doi.org/10.1098/rstb.2019.0580

Author

Bravo-Lopez, Miriam ; Villa-Islas, Viridiana ; Rocha Arriaga, Carolina ; Villasenor-Altamirano, Ana B. ; Guzman-Solis, Axel ; Sandoval-Velasco, Marcela ; Wesp, Julie K. ; Alcantara, Keitlyn ; Lopez-Corral, Aurelio ; Gomez-Valdes, Jorge ; Mejia, Elizabeth ; Herrera, Alberto ; Meraz-Moreno, Alejandro ; Moreno-Cabrera, Maria de la Luz ; Moreno-Estrada, Andres ; Nieves-Colon, Maria A. ; Olvera, Joel ; Perez-Perez, Julia ; Iversen, Katrine Hojholt ; Rasmussen, Simon ; Sandoval, Karla ; Zepeda, Gabriela ; Avila-Arcos, Maria C. / Paleogenomic insights into the red complex bacteria Tannerella forsythia in Pre-Hispanic and Colonial individuals from Mexico. In: Philosophical Transactions of the Royal Society B: Biological Sciences. 2020 ; Vol. 375, No. 1812.

Bibtex

@article{51bd009472a84499bad83d9d09d215ef,
title = "Paleogenomic insights into the red complex bacteria Tannerella forsythia in Pre-Hispanic and Colonial individuals from Mexico",
abstract = "The 'red complex' is an aggregate of three oral bacteria (Tannerella forsythia, Porphyromonas gingivalis and Treponema denticola) responsible for severe clinical manifestation of periodontal disease. Here, we report the first direct evidence of ancient T.forsythia DNA in dentin and dental calculus samples from archaeological skeletal remains that span from the Pre-Hispanic to the Colonial period in Mexico. We recovered twelve partial ancient T. forsythia genomes and observed a distinct phylogenetic placement of samples, suggesting that the strains present in Pre-Hispanic individuals likely arrived with the first human migrations to the Americas and that new strains were introduced with the arrival of European and African populations in the sixteenth century. We also identified instances of the differential presence of genes between periods in the T. forsythia ancient genomes, with certain genes present in Pre-Hispanic individuals and absent in Colonial individuals, and vice versa. This study highlights the potential for studying ancient T. forsythia genomes to unveil past social interactions through analysis of disease transmission. Our results illustrate the long-standing relationship between this oral pathogen and its human host, while also unveiling key evidence to understand its evolutionary history in Pre-Hispanic and Colonial Mexico.This article is part of the theme issue 'Insights into health and disease from ancient biomolecules'.",
keywords = "paleogenomics, Tannerella forsythia, ancient pathogens, periodontal disease, red complex, capture-enrichment, ANCIENT DNA, S-LAYER, ALIGNMENT, SEQUENCE, PERFORMANCE, DISEASE, GENOMES, TOOL",
author = "Miriam Bravo-Lopez and Viridiana Villa-Islas and {Rocha Arriaga}, Carolina and Villasenor-Altamirano, {Ana B.} and Axel Guzman-Solis and Marcela Sandoval-Velasco and Wesp, {Julie K.} and Keitlyn Alcantara and Aurelio Lopez-Corral and Jorge Gomez-Valdes and Elizabeth Mejia and Alberto Herrera and Alejandro Meraz-Moreno and Moreno-Cabrera, {Maria de la Luz} and Andres Moreno-Estrada and Nieves-Colon, {Maria A.} and Joel Olvera and Julia Perez-Perez and Iversen, {Katrine Hojholt} and Simon Rasmussen and Karla Sandoval and Gabriela Zepeda and Avila-Arcos, {Maria C.}",
year = "2020",
doi = "10.1098/rstb.2019.0580",
language = "English",
volume = "375",
journal = "Philosophical Transactions of the Royal Society B: Biological Sciences",
issn = "0962-8436",
publisher = "The/Royal Society",
number = "1812",

}

RIS

TY - JOUR

T1 - Paleogenomic insights into the red complex bacteria Tannerella forsythia in Pre-Hispanic and Colonial individuals from Mexico

AU - Bravo-Lopez, Miriam

AU - Villa-Islas, Viridiana

AU - Rocha Arriaga, Carolina

AU - Villasenor-Altamirano, Ana B.

AU - Guzman-Solis, Axel

AU - Sandoval-Velasco, Marcela

AU - Wesp, Julie K.

AU - Alcantara, Keitlyn

AU - Lopez-Corral, Aurelio

AU - Gomez-Valdes, Jorge

AU - Mejia, Elizabeth

AU - Herrera, Alberto

AU - Meraz-Moreno, Alejandro

AU - Moreno-Cabrera, Maria de la Luz

AU - Moreno-Estrada, Andres

AU - Nieves-Colon, Maria A.

AU - Olvera, Joel

AU - Perez-Perez, Julia

AU - Iversen, Katrine Hojholt

AU - Rasmussen, Simon

AU - Sandoval, Karla

AU - Zepeda, Gabriela

AU - Avila-Arcos, Maria C.

PY - 2020

Y1 - 2020

N2 - The 'red complex' is an aggregate of three oral bacteria (Tannerella forsythia, Porphyromonas gingivalis and Treponema denticola) responsible for severe clinical manifestation of periodontal disease. Here, we report the first direct evidence of ancient T.forsythia DNA in dentin and dental calculus samples from archaeological skeletal remains that span from the Pre-Hispanic to the Colonial period in Mexico. We recovered twelve partial ancient T. forsythia genomes and observed a distinct phylogenetic placement of samples, suggesting that the strains present in Pre-Hispanic individuals likely arrived with the first human migrations to the Americas and that new strains were introduced with the arrival of European and African populations in the sixteenth century. We also identified instances of the differential presence of genes between periods in the T. forsythia ancient genomes, with certain genes present in Pre-Hispanic individuals and absent in Colonial individuals, and vice versa. This study highlights the potential for studying ancient T. forsythia genomes to unveil past social interactions through analysis of disease transmission. Our results illustrate the long-standing relationship between this oral pathogen and its human host, while also unveiling key evidence to understand its evolutionary history in Pre-Hispanic and Colonial Mexico.This article is part of the theme issue 'Insights into health and disease from ancient biomolecules'.

AB - The 'red complex' is an aggregate of three oral bacteria (Tannerella forsythia, Porphyromonas gingivalis and Treponema denticola) responsible for severe clinical manifestation of periodontal disease. Here, we report the first direct evidence of ancient T.forsythia DNA in dentin and dental calculus samples from archaeological skeletal remains that span from the Pre-Hispanic to the Colonial period in Mexico. We recovered twelve partial ancient T. forsythia genomes and observed a distinct phylogenetic placement of samples, suggesting that the strains present in Pre-Hispanic individuals likely arrived with the first human migrations to the Americas and that new strains were introduced with the arrival of European and African populations in the sixteenth century. We also identified instances of the differential presence of genes between periods in the T. forsythia ancient genomes, with certain genes present in Pre-Hispanic individuals and absent in Colonial individuals, and vice versa. This study highlights the potential for studying ancient T. forsythia genomes to unveil past social interactions through analysis of disease transmission. Our results illustrate the long-standing relationship between this oral pathogen and its human host, while also unveiling key evidence to understand its evolutionary history in Pre-Hispanic and Colonial Mexico.This article is part of the theme issue 'Insights into health and disease from ancient biomolecules'.

KW - paleogenomics

KW - Tannerella forsythia

KW - ancient pathogens

KW - periodontal disease

KW - red complex

KW - capture-enrichment

KW - ANCIENT DNA

KW - S-LAYER

KW - ALIGNMENT

KW - SEQUENCE

KW - PERFORMANCE

KW - DISEASE

KW - GENOMES

KW - TOOL

U2 - 10.1098/rstb.2019.0580

DO - 10.1098/rstb.2019.0580

M3 - Journal article

C2 - 33012233

VL - 375

JO - Philosophical Transactions of the Royal Society B: Biological Sciences

JF - Philosophical Transactions of the Royal Society B: Biological Sciences

SN - 0962-8436

IS - 1812

M1 - 20190580

ER -

ID: 250432323