Rasmus Nielsen
Professor
Section for Geogenetics
Øster Voldgade 5-7, 1350 København K
Section for Geogenetics
Øster Voldgade 5-7
1350 København K
- 2015
Association mapping for compound heterozygous traits using phenotypic distance and integer programming
Gusfield, D. & Nielsen, Rasmus, 1 Jan 2015, Algorithms in Bioinformatics - 15th International Workshop, WABI 2015, Proceedings. Pop, M. & Touzet, H. (eds.). Springer Verlag, p. 136-147 12 p. A1. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), Vol. 9289).Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
- Published
A recent bottleneck of Y chromosome diversity coincides with a global change in culture
Karmin, M., Saag, L., Vicente, M., Wilson Sayres, M. A., Järve, M., Talas, U. G., Rootsi, S., Ilumäe, A-M., Mägi, R., Mitt, M., Pagani, L., Puurand, T., Faltyskova, Z., Clemente, F., Cardona, A., Metspalu, E., Sahakyan, H., Yunusbayev, B., Hudjashov, G., DeGiorgio, M. & 80 others, , 2015, In: Genome Research. 25, 4, p. 459-466 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic evidence for the Pleistocene and recent population history of Native Americans
Raghavan, M., Steinrücken, M., Harris, K., Schiffels, S., Rasmussen, S., DeGiorgio, M., Albrechtsen, A., Valdiosera Morales, C. E., Avila Arcos, M. D. C., Malaspinas, A. S., Eriksson, A., Moltke, I., Metspalu, M., Homburger, J. R., Wall, J., Cornejo, O. E., Moreno Mayar, J. V., Korneliussen, T. S., Pierre, T. L., Rasmussen, M. & 81 others, , 2015, In: Science (New York, N.Y.). 349, 6250, 6250.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Greenlandic Inuit show genetic signatures of diet and climate adaptation
Fumagalli, M., Moltke, Ida, Grarup, Niels, Racimo, F., Bjerregaard, P., Jørgensen, M. E., Korneliussen, Thorfinn Sand, Gerbault, P., Skotte, L., Linneberg, Allan René, Christensen, C., Brandslund, I., Jørgensen, T., Huerta-Sánchez, E., Schmidt, E. B., Pedersen, Oluf Borbye, Hansen, T., Albrechtsen, Anders & Nielsen, Rasmus, 2015, In: Science (New York, N.Y.). 349, 6254, p. 1343-1347 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phylogenetic ANOVA: the expression variance and evolution model for quantitative trait evolution
Rohlfs, R. V. & Nielsen, Rasmus, 2015, In: Systematic Biology. 64, 5, p. 695-708 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Population genomics of bronze age Eurasia
Allentoft, M. E., Sikora, M., Sjogren, K-G., Rasmussen, S., Rasmussen, M., Stenderup, J., Damgaard, P. D. B., Schroeder, H., Ahlstrom, T., Vinner, L., Malaspinas, A. S., Margaryan, A., Higham, T., Chivall, D., Lynnerup, N., Harvig, L. L., Baron, J., Della Casa, P., Dabrowski, P., Duffy, P. R. & 46 others, , 2015, In: Nature Genetics. 522, 7555, p. 167-172 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The ancestry and affiliations of Kennewick Man
Rasmussen, M., Sikora, Martin, Albrechtsen, Anders, Korneliussen, Thorfinn Sand, Moreno Mayar, J. Víctor, Poznik, G. D., Zollikofer, C. P. E., Ponce de León, M. S., Allentoft, Morten Erik, Moltke, Ida, Jónsson, H., Valdiosera Morales, C. E., Malhi, R. S., Orlando, L. A. A., Bustamante, C. D., Stafford jr., T., Meltzer, D. J., Nielsen, Rasmus & Willerslev, Eske, 2015, In: Nature. 523, 7561, p. 455-458 4 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
The origin and evolution of maize in the Southwestern United States: [+ erratum]
Rodrigues da Fonseca, Rute Andreia, Smith, B. D., Wales, N., Cappellini, Enrico, Skoglund, P., Fumagalli, M., Samaniego Castruita, J. A., Carøe, C., Avila Arcos, M. D. C., Hufnagel, D. E., Korneliussen, Thorfinn Sand, Vieira, Filipe Garrett, Jakobsson, M., Arriaza, B., Willerslev, Eske, Nielsen, Rasmus, Hufford, M. B., Albrechtsen, Anders, Ross-Ibarra, J. & Gilbert, M Thomas P, 2015, In: Nature Plants. 1, 5 p., 14003.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Uncovering the genetic history of the present-day greenlandic population
Moltke, Ida, Fumagalli, M., Korneliussen, Thorfinn Sand, Crawford, J. E., Bjerregaard, P., Jørgensen, M. E., Grarup, Niels, Gulløv, H. C., Linneberg, Allan René, Pedersen, Oluf Borbye, Hansen, Torben, Nielsen, Rasmus & Albrechtsen, Anders, 2015, In: American Journal of Human Genetics. 96, 1, p. 54-69 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Error-prone polymerase activity causes multinucleotide mutations in humans
Harris, K. & Nielsen, Rasmus, 1 Sep 2014, In: Genome Research. 24, 9, p. 1445-1454 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
bammds: a tool for assessing the ancestry of low-depth whole-genome data using multidimensional scaling (MDS)
Malaspinas, A. S., Tange, O., Moreno Mayar, J. Víctor, Rasmussen, M., DiGiorgio, M., Wang, Y., Valdiosera Morales, C. E., Politis, G., Willerslev, Eske & Nielsen, Rasmus, 2014, In: Bioinformatics. 30, 20, p. 2962-2964 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ngsTools : methods for population genetics analyses from next-generation sequencing data
Fumagalli, M., Vieira, Filipe Garrett, Linderoth, T. & Nielsen, Rasmus, 2014, In: Bioinformatics. 30, 10, p. 1486-1487 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ANGSD: analysis of next generation sequencing data
Korneliussen, Thorfinn Sand, Albrechtsen, Anders & Nielsen, Rasmus, 2014, In: B M C Bioinformatics. 15, 13 p., 356.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNA
Huerta-Sanchez, E., Jin, X., Asan, Bianba, Z., Peter, B. M., Vinckenbosch, N., Liang, Y., Yi, X., He, M., Somel, M., Ni, P., Wang, B., Ou, X., Huasang, Luosang, J., Cuo, Z. X. P., Li, K., Gao, G., Yin, Y., Wang, W. & 7 others, , 2014, In: Nature. 512, 7513, p. 194-197 4 p.Research output: Contribution to journal › Letter › Research › peer-review
Classic Selective Sweeps Revealed by Massive Sequencing in Cattle
Qanbari, S., Pausch, H., Jansen, S., Somel, M., Strom, T. M., Fries, R., Nielsen, Rasmus & Simianer, H., 2014, In: PLOS Genetics. 10, 2, 13 p., e1004148.Research output: Contribution to journal › Journal article › Research › peer-review
Costs and benefits of mutational robustness in RNA viruses
Stern, A., Bianco, S., Yeh, M. T., Wright, C., Butcher, K., Tang, C., Nielsen, Rasmus & Andino, R., 2014, In: Cell Reports. 8, 4, p. 1026-1036 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide Ancestry Patterns in Rapanui Suggest Pre-European Admixture with Native Americans
Moreno Mayar, J. Víctor, Rasmussen, Simon, Seguin-Orlando, A., Rasmussen, M., Liang, M., Flåm, S. T., Lie, B. A., Gilfillan, G. D., Nielsen, Rasmus, Thorsby, E., Willerslev, Eske & Malaspinas, A., 2014, In: Current Biology. 24, 21, p. 2518-2525Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal age effect and severe germ-line bottleneck in the inheritance of human mitochondrial DNA
Rebolledo-Jaramillo, B., Su, M. S., Stoler, N., McElhoe, J. A., Dickins, B., Blankenberg, D., Korneliussen, Thorfinn Sand, Chiaromonte, F., Nielsen, Rasmus, Holland, M. M., Paul, I. M., Nekrutenko, A. & Makova, K. D., 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 43, p. 15474-15479 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Modeling gene expression evolution with an extended ornstein-uhlenbeck process accounting for within-species variation
Rohlfs, R. V., Harrigan, P. & Nielsen, Rasmus, 2014, In: Molecular Biology and Evolution. 31, 1, p. 201-211 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Natural Selection Reduced Diversity on Human Y Chromosomes
Wilson Sayres, M. A., Lohmueller, K. E. & Nielsen, Rasmus, 2014, In: PLOS Genetics. 10, 1, 12 p., e1004064.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On detecting incomplete soft or hard selective sweeps using haplotype structure
Ferrer-Admetlla, A., Liang, M., Korneliussen, Thorfinn Sand & Nielsen, Rasmus, 2014, In: Molecular Biology and Evolution. 31, 5, p. 1275-1291 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Population genomics reveal recent speciation and rapid evolutionary adaptation in polar bears
Liu, S., Lorenzen, E., Fumagalli, M., Li, B., Harris, K., Xiong, Z., Zhou, L., Korneliussen, T. S., Somel, M., Babbitt, C., Wray, G., Li, J., He, W., Wang, Z., Fu, W., Xiang, X., Morgan, C. C., Doherty, A., O'Connell, M. J., McInerney, J. O. & 9 others, , 2014, In: Cell. 157, 4, p. 785-794 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Selection on a Variant Associated with Improved Viral Clearance Drives Local, Adaptive Pseudogenization of Interferon Lambda 4 (IFNL4)
Key, F. M., Peter, B., Dennis, M. Y., Huerta-Sánchez, E., Tang, W., Prokunina-Olsson, L., Nielsen, Rasmus & Andrés, A. M., 2014, In: PLOS Genetics. 10, 10, 12 p., e1004681.Research output: Contribution to journal › Journal article › Research › peer-review
The lengths of admixture tracts
Liang, M. & Nielsen, Rasmus, 2014, In: Genetics. 197, 3, p. 953-967 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two ancient human genomes reveal Polynesian ancestry among the indigenous Botocudos of Brazil
Malaspinas, A. S., Lao, O., Schroeder, H., Rasmussen, M., Raghavan, M., Moltke, I., Campos, P., Sagredo, F. S., Rasmussen, S., Gonçalves, V. F., Albrechtsen, A., Allentoft, M. E., Johnson, P. L. F., Li, M., Reis, S., Bernardo, D. V., DeGiorgio, M., Duggan, A. T., Bastos, M., Wang, Y. & 20 others, , 2014, In: Current biology : CB. 24, 21, p. R1035-R1037 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variation and association to diabetes in 2000 full mtDNA sequences mined from an exome study in a Danish population
Li, S., Besenbacher, S., Li, Y., Kristiansen, Karsten, Grarup, Niels, Albrechtsen, Anders, Sparsø, T. H., Korneliussen, Thorfinn Sand, Hansen, Torben, Wang, J., Nielsen, Rasmus, Pedersen, Oluf Borbye, Bolund, L. & Schierup, M. H., 2014, In: European Journal of Human Genetics. 22, p. 1040-1045 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes
Lohmueller, K. E., Sparsø, T. H., Li, Q., Galijatovic, E. A. A., Korneliussen, T. S., Albrechtsen, A., Banasik, K., Grarup, N., Hallgrimsdottir, I., Kiil, K., Oskari Kilpeläinen, T., Krarup, N. T., Pers, T. H., Sanchez, G., Hu, Y., DeGiorgio, M., Jørgensen, T., Sandbæk, A., Lauritzen, T., Brunak, S. & 6 others, , 5 Dec 2013, In: American Journal of Human Genetics. 93, 6, p. 1072-1086 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bacterial natural transformation by highly fragmented and damaged DNA
Overballe-Petersen, S., Harms, K., Orlando, L. A. A., Moreno Mayar, J. Víctor, Rasmussen, Simon, Dahl, Tais Wittchen, Rosing, Minik Thorleif, Poole, A. M., Sicheritz-Ponten, T., Brunak, S., Inselmann, S., de Vries, J., Wackernagel, W., Pybus, O. G., Nielsen, Rasmus, Johnsen, P. J., Nielsen, K. M. & Willerslev, Eske, 3 Dec 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 49, p. 19860–19865 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantifying population genetic differentiation from next-generation sequencing data
Fumagalli, M., Vieira, Filipe Garrett, Korneliussen, Thorfinn Sand, Linderoth, T., Huerta-Sánchez, E., Albrechtsen, Anders & Nielsen, Rasmus, Nov 2013, In: Genetics. 195, 3, p. 979-992 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
A scan for human-specific relaxation of negative selection reveals unexpected Polymorphism in Proteasome Genes
Somel, M., Sayres, M. A. W., Jordan, G., Huerta-Sanchez, E., Fumagalli, M., Ferrer-Admetlla, A. & Nielsen, Rasmus, 2013, In: Molecular Biology and Evolution. 30, 8, p. 1808-1815 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Calculation of Tajima's D and other neutrality test statistics from low depth next-generation sequencing data
Korneliussen, Thorfinn Sand, Moltke, Ida, Albrechtsen, Anders & Nielsen, Rasmus, 2013, In: B M C Bioinformatics. 14, 14 p., 289.Research output: Contribution to journal › Journal article › Research › peer-review
Detecting adaptive trait loci in nonmodel systems: divergence or admixture mapping?
Crawford, J. E. & Nielsen, Rasmus, 2013, In: Molecular Ecology. 22, 24, p. 6131-6148 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimating inbreeding coefficients from NGS data: impact on genotype calling and allele frequency estimation
Vieira, Filipe Garrett, Fumagalli, M., Albrechtsen, Anders & Nielsen, Rasmus, 2013, In: Genome Research. 23, p. 1852-1861 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes
Albrechtsen, A., Grarup, N., Li, Y., Sparsø, T. H., Tian, G., Cao, H., Jiang, T., Kim, S. Y., Korneliussen, T. S., Li, Q., Nie, C., Wu, R., Skotte, L., Morris, A. P., Ladenvall, C., Cauchi, S., Stancáková, A., Andersen, G., Astrup, A., Banasik, K. & 86 others, , 2013, In: Diabetologia. 56, 2, p. 298-310 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
Grarup, N., Sulem, P., Sandholt, C. H., Thorleifsson, G., Ahluwalia, T. V. S., Steinthorsdottir, V., Bjarnason, H., Gudbjartsson, D. F., Magnusson, O. T., Sparsø, T., Albrechtsen, A., Kong, A., Masson, G., Tian, G., Cao, H., Nie, C., Kristiansen, K., Husemoen, L. L., Thuesen, B., Li, Y. & 10 others, , 2013, In: P L o S Genetics. 9, 6, 12 p., e1003530.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic signatures reveal high-altitude adaptation in a set of Ethiopian populations
Huerta-Sánchez, E., DeGiorgio, M., Pagani, L., Tarekegn, A., Ekong, R., Antao, T., Cardona, A., Montgomery, H. E., Cavalleri, G. L., Robbins, P. A., Weale, M. E., Bradman, N., Bekele, E., Kivisild, T., Tyler-Smith, C. & Nielsen, Rasmus, 2013, In: Molecular Biology and Evolution. 30, 8, p. 1877-1888 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inferring demographic history from a spectrum of shared haplotype lengths
Harris, K. & Nielsen, Rasmus, 2013, In: P L o S Genetics. 9, 6, 20 p., e1003521.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular footprints of domestication and improvement in soybean revealed by whole genome re-sequencing
Li, Y., Zhao, S., Ma, J., Li, D., Yan, L., Li, J., Qi, X., Guo, X., Zhang, L., He, W., Chang, R., Liang, Q., Guo, Y., Ye, C., Wang, X., Tao, Y., Guan, R., Wang, J., Liu, Y., Jin, L. & 15 others, , 2013, In: BMC Genomics. 14, 12 p., 579.Research output: Contribution to journal › Journal article › Research › peer-review
Unlocking the vault: next-generation museum population genomics
Bi, K., Linderoth, T., Vanderpool, D., Good, J. M., Nielsen, Rasmus & Moritz, C., 2013, In: Molecular Ecology. 22, 24, p. 6018-6032 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
Evidence for Positive Selection on a Number of MicroRNA Regulatory Interactions during Recent Human Evolution
Li, J., Liu, Y., Xin, X., Kim, T. S., Cabeza, E. A., Ren, J., Nielsen, Rasmus, Wrana, J. L. & Zhang, Z., 1 Mar 2012, In: P L o S Genetics (Online). 8, 3Research output: Contribution to journal › Journal article › Research › peer-review
Distinguishing between Selective Sweeps from Standing Variation and from a De Novo Mutation
Peter, B. M., Huerta-Sanchez, E. & Nielsen, Rasmus, 2012, In: P L o S Genetics (Online). 8, 10, p. 1-14 14 p., e1003011.Research output: Contribution to journal › Journal article › Research › peer-review
Estimating population divergence time and phylogeny from single-nucleotide polymorphisms data with outgroup ascertainment bias
Wang, Y. & Nielsen, Rasmus, 2012, In: Molecular Ecology. 21, 4, p. 974-986 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Looking for Darwin in Genomic Sequences-Validity and Success of Statistical Methods
Zhai, W., Nielsen, Rasmus, Goldman, N. & Yang, Z., 2012, In: Molecular Biology and Evolution. 29, 10, p. 2889-2893 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Resequencing 50 accessions of cultivated and wild rice yields markers for identifying agronomically important genes
Xu, X., Liu, X., Ge, S., Jensen, J. D., Hu, F., Li, X., Dong, Y., Gutenkunst, R. N., Fang, L., Huang, L., Li, J., He, W., Zhang, G., Zheng, X., Zhang, F., Li, Y., Yu, C., Kristiansen, K., Zhang, X., Wang, J. & 5 others, , 2012, In: Nature Biotechnology. 30, 1, p. 105-111 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SNP calling, genotype calling, and sample allele frequency estimation from new-generation sequencing data
Nielsen, Rasmus, Korneliussen, Thorfinn Sand, Albrechtsen, Anders, Li, Y. & Wang, J., 2012, In: PLoS ONE. 7, 7, 11 p., e37558.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
Signatures of Environmental Genetic Adaptation Pinpoint Pathogens as the Main Selective Pressure through Human Evolution
Fumagalli, M., Sironi, M., Pozzoli, U., Ferrer-Admettla, A., Pattini, L. & Nielsen, Rasmus, 1 Nov 2011, In: P L o S Genetics. 7, 11Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The evolution of gene expression levels in mammalian organs
Brawand, D., Soumillon, M., Necsulea, A., Julien, P., Csardi, G., Harrigan, P., Weier, M., Liechti, A., Aximu-Petri, A., Kircher, M., Albert, F. W., Zeller, U., Khaitovich, P., Gruetzner, F., Bergmann, S., Nielsen, Rasmus, Paeaebo, S. & Kaessmann, H., 20 Oct 2011, In: Nature. 478, 7369, p. 343-348 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Q A: Who is H. sapiens really, and how do we know?
Liang, M. & Nielsen, Rasmus, 31 Mar 2011, In: B M C Biology. 9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A method for detecting IBD regions simultaneously in multiple individuals--with applications to disease genetics
Moltke, Ida, Albrechtsen, Anders, Hansen, Thomas van Overeem, Nielsen, Finn Cilius & Nielsen, Rasmus, 2011, In: Genome Research. 21, 7, p. 1168-80 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An Aboriginal Australian genome reveals separate human dispersals into Asia
Rasmussen, M., Guo, X., Wang, Y., Lohmueller, K. E., Rasmussen, S., Albrechtsen, A., Skotte, L., Lindgreen, S., Metspalu, M., Jombart, T., Kivisild, T., Zhai, W., Eriksson, A., Manica, A., Orlando, L., De La Vega, F. M., Tridico, S., Metspalu, E., Nielsen, K., Avila Arcos, M. D. C. & 38 others, , 2011, In: Science. 334, 6052, p. 94-98 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 3311
Most downloads
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5475
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
5230
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
3400
downloads
SNP calling, genotype calling, and sample allele frequency estimation from new-generation sequencing data
Research output: Contribution to journal › Journal article › Research › peer-review
Published