Male-biased gene expression resolves sexual conflict through the evolution of sex-specific genetic architecture

Research output: Contribution to journal › Letter › Research › peer-review

Standard

Male-biased gene expression resolves sexual conflict through the evolution of sex-specific genetic architecture. / Wright, Alison E; Fumagalli, Matteo; Cooney, Christopher R; Bloch, Natasha I; Vieira, Filipe G; Buechel, Severine D; Kolm, Niclas; Mank, Judith E.

In: Evolution Letters, Vol. 2, No. 2, 04.2018, p. 52-61.

Research output: Contribution to journal › Letter › Research › peer-review

Harvard

Wright, AE, Fumagalli, M, Cooney, CR, Bloch, NI, Vieira, FG, Buechel, SD, Kolm, N & Mank, JE 2018, 'Male-biased gene expression resolves sexual conflict through the evolution of sex-specific genetic architecture', Evolution Letters, vol. 2, no. 2, pp. 52-61. https://doi.org/10.1002/evl3.39

APA

Wright, A. E., Fumagalli, M., Cooney, C. R., Bloch, N. I., Vieira, F. G., Buechel, S. D., Kolm, N., & Mank, J. E. (2018). Male-biased gene expression resolves sexual conflict through the evolution of sex-specific genetic architecture. Evolution Letters, 2(2), 52-61. https://doi.org/10.1002/evl3.39

Vancouver

Wright AE, Fumagalli M, Cooney CR, Bloch NI, Vieira FG, Buechel SD et al. Male-biased gene expression resolves sexual conflict through the evolution of sex-specific genetic architecture. Evolution Letters. 2018 Apr;2(2):52-61. https://doi.org/10.1002/evl3.39

Author

Wright, Alison E ; Fumagalli, Matteo ; Cooney, Christopher R ; Bloch, Natasha I ; Vieira, Filipe G ; Buechel, Severine D ; Kolm, Niclas ; Mank, Judith E. / Male-biased gene expression resolves sexual conflict through the evolution of sex-specific genetic architecture. In: Evolution Letters. 2018 ; Vol. 2, No. 2. pp. 52-61.

Bibtex

@article{6bc92d0f3709459ab5a3daf671677f38,
title = "Male-biased gene expression resolves sexual conflict through the evolution of sex-specific genetic architecture",
abstract = "Many genes are subject to contradictory selection pressures in males and females, and balancing selection resulting from sexual conflict has the potential to substantially increase standing genetic diversity in populations and thereby act as an important force in adaptation. However, the underlying causes of sexual conflict, and the potential for resolution, remains hotly debated. Using transcriptome-resequencing data from male and female guppies, we use a novel approach, combining patterns of genetic diversity and intersexual divergence in allele frequency, to distinguish the different scenarios that give rise to sexual conflict, and how this conflict may be resolved through regulatory evolution. We show that reproductive fitness is the main source of sexual conflict, and this is resolved via the evolution of male-biased expression. Furthermore, resolution of sexual conflict produces significant differences in genetic architecture between males and females, which in turn lead to specific alleles influencing sex-specific viability. Together, our findings suggest an important role for sexual conflict in shaping broad patterns of genome diversity, and show that regulatory evolution is a rapid and efficient route to the resolution of conflict.",
author = "Wright, {Alison E} and Matteo Fumagalli and Cooney, {Christopher R} and Bloch, {Natasha I} and Vieira, {Filipe G} and Buechel, {Severine D} and Niclas Kolm and Mank, {Judith E}",
year = "2018",
month = apr,
doi = "10.1002/evl3.39",
language = "English",
volume = "2",
pages = "52--61",
journal = "Evolution Letters",
issn = "2056-3744",
publisher = "Wiley",
number = "2",

}

RIS

TY - JOUR

T1 - Male-biased gene expression resolves sexual conflict through the evolution of sex-specific genetic architecture

AU - Wright, Alison E

AU - Fumagalli, Matteo

AU - Cooney, Christopher R

AU - Bloch, Natasha I

AU - Vieira, Filipe G

AU - Buechel, Severine D

AU - Kolm, Niclas

AU - Mank, Judith E

PY - 2018/4

Y1 - 2018/4

N2 - Many genes are subject to contradictory selection pressures in males and females, and balancing selection resulting from sexual conflict has the potential to substantially increase standing genetic diversity in populations and thereby act as an important force in adaptation. However, the underlying causes of sexual conflict, and the potential for resolution, remains hotly debated. Using transcriptome-resequencing data from male and female guppies, we use a novel approach, combining patterns of genetic diversity and intersexual divergence in allele frequency, to distinguish the different scenarios that give rise to sexual conflict, and how this conflict may be resolved through regulatory evolution. We show that reproductive fitness is the main source of sexual conflict, and this is resolved via the evolution of male-biased expression. Furthermore, resolution of sexual conflict produces significant differences in genetic architecture between males and females, which in turn lead to specific alleles influencing sex-specific viability. Together, our findings suggest an important role for sexual conflict in shaping broad patterns of genome diversity, and show that regulatory evolution is a rapid and efficient route to the resolution of conflict.

AB - Many genes are subject to contradictory selection pressures in males and females, and balancing selection resulting from sexual conflict has the potential to substantially increase standing genetic diversity in populations and thereby act as an important force in adaptation. However, the underlying causes of sexual conflict, and the potential for resolution, remains hotly debated. Using transcriptome-resequencing data from male and female guppies, we use a novel approach, combining patterns of genetic diversity and intersexual divergence in allele frequency, to distinguish the different scenarios that give rise to sexual conflict, and how this conflict may be resolved through regulatory evolution. We show that reproductive fitness is the main source of sexual conflict, and this is resolved via the evolution of male-biased expression. Furthermore, resolution of sexual conflict produces significant differences in genetic architecture between males and females, which in turn lead to specific alleles influencing sex-specific viability. Together, our findings suggest an important role for sexual conflict in shaping broad patterns of genome diversity, and show that regulatory evolution is a rapid and efficient route to the resolution of conflict.

U2 - 10.1002/evl3.39

DO - 10.1002/evl3.39

M3 - Letter

C2 - 30283664

VL - 2

SP - 52

EP - 61

JO - Evolution Letters

JF - Evolution Letters

SN - 2056-3744

IS - 2

ER -

ID: 203874397