Rasmus Nielsen
Professor
Section for Geogenetics
Øster Voldgade 5-7, 1350 København K
Section for Geogenetics
Øster Voldgade 5-7
1350 København K
- Published
100 ancient genomes show repeated population turnovers in Neolithic Denmark
Allentoft, M. E., Sikora, M., Fischer, A., Sjögren, K-G., Ingason, A., Macleod, R., Rosengren, A., Schulz Paulsson, B., Jørkov, M. L. S., Novosolov, M., Stenderup, J., Price, T. D., Mortensen, M. F., Nielsen, A. B., Hede, M. U., Sørensen, L., Nielsen, P. O., Rasmussen, P., Jensen, T. Z. T., Refoyo-Martínez, A. & 48 others, , 2024, In: Nature. 625, 7994, p. 329-337 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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137 ancient human genomes from across the Eurasian steppes
Damgaard, P. D. B., Marchi, N., Rasmussen, S., Peyrot, M., Renaud, G., Korneliussen, T. S., Moreno-Mayar, J. V., Pedersen, M. W., Goldberg, A., Usmanova, E., Baimukhanov, N., Loman, V., Hedeager, L., Pedersen, A. G., Nielsen, K., Afanasievl, G., Akmatov, K., Aldashev, A., Alpaslan, A., Baimbetov, G. & 55 others, , 2018, In: Nature. 557, 7705, p. 369-374 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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bammds: a tool for assessing the ancestry of low-depth whole-genome data using multidimensional scaling (MDS)
Malaspinas, A. S., Tange, O., Moreno Mayar, J. Víctor, Rasmussen, M., DiGiorgio, M., Wang, Y., Valdiosera Morales, C. E., Politis, G., Willerslev, Eske & Nielsen, Rasmus, 2014, In: Bioinformatics. 30, 20, p. 2962-2964 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ngsTools : methods for population genetics analyses from next-generation sequencing data
Fumagalli, M., Vieira, Filipe Garrett, Linderoth, T. & Nielsen, Rasmus, 2014, In: Bioinformatics. 30, 10, p. 1486-1487 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
A Bayesian Framework for Inferring the Influence of Sequence Context on Point Mutations
Ling, G., Miller, D., Nielsen, Rasmus & Stern, A., 2020, In: Molecular Biology and Evolution. 37, 3, p. 893-903 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A Bayesian multilocus association method: allowing for higher-order interaction in association studies
Albrechtsen, Anders, Castella, S., Andersen, G., Hansen, T., Pedersen, O. & Nielsen, Rasmus, 2007, In: Genetics. 176, 2, p. 1197-208 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Scan for Positively Selected Genes in the Genomes of Humans and Chimpanzees
Nielsen, Rasmus, Bustamente, C., Clark, A. G., Glanowski, S., Sackton, T. B., Hubisz, M. J., Fledel-Alon, A., Tanenbaum, D. M., Civello, D., White, T. J., Sninsky, J. J., Adams, M. D. & Cargill, M., 2005, In: PLoS - Biology. 3, 6, p. e170Research output: Contribution to journal › Journal article › Research › peer-review
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A draft genome sequence of the elusive giant squid, Architeuthis dux
da Fonseca, R. R., Couto, A., Machado, A. M., Brejova, B., Albertin, C. B., Silva, F., Gardner, P., Baril, T., Hayward, A., Campos, A., Ribeiro, Â. M., Barrio-Hernandez, I., Hoving, H-J., Tafur-Jimenez, R., Chu, C., Frazão, B., Petersen, B., Peñaloza, F., Musacchia, F., Alexander, G. C. & 24 others, , 2020, In: GigaScience. 9, 1, 12 p., giz152.Research output: Contribution to journal › Journal article › Research › peer-review
A draft sequence of the neandertal genome
Green, R. E., Krause, J., Briggs, A. W., Maricic, T., Stenzel, U., Kircher, M., Patterson, N., Li, H., Zhai, W., Fritz, M. H. Y., Hansen, N. F., Durand, E. Y., Malaspinas, A-S., Jensen, J. D., Marques-Bonet, T., Alkan, C., Prüfer, K., Meyer, M., Burbano, H. A., Good, J. M. & 36 others, , 2010, In: Science. 328, 5979, p. 710-722 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
A genome-wide scan for signatures of directional selection in domesticated pigs
Moon, S., Kim, T. H., Lee, K. T., Kwak, W., Lee, T., Lee, S. W., Kim, M. J., Cho, K., Kim, N., Chung, W. H., Sung, S., Park, T., Cho, S., Groenen, M. A. M., Nielsen, Rasmus, Kim, Y. & Kim, H., 25 Feb 2015, In: BMC Genomics. 16, 1, 130.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A genomic history of aboriginal Australia
Malaspinas, A. S., Westaway, M. C., Muller, C. E., Sousa, V. C., Lao, O., Alves, I., Bergström, A., Athanasiadis, G., Cheng, J. Y., Crawford, J. E., Heupink, T. H., Macholdt, E., Peischl, S., Rasmussen, S., Schiffels, S., Subramanian, S., Wright, J. L., Albrechtsen, A., Barbieri, C., Dupanloup, I. & 55 others, , 2016, In: Nature. 538, 7624, p. 207-214 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A hidden Markov model approach for simultaneously estimating local ancestry and admixture time using next generation sequence data in samples of arbitrary ploidy
Corbett-Detig, R. & Nielsen, Rasmus, 3 Jan 2017, In: PLoS Genetics. 13, 1, 40 p., e1006529.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A likelihood method for estimating present-day human contamination in ancient male samples using low-depth X-chromosome data
Moreno-Mayar, J. V., Korneliussen, Thorfinn Sand, Dalal, J., Renaud, Gabriel, Albrechtsen, Anders, Nielsen, Rasmus & Malaspinas, A., 2020, In: Bioinformatics. 36, 3, p. 828-841 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A likelihood ratio test for species membership based on DNA sequence data
Matz, M. V. & Nielsen, Rasmus, 2005, In: Philosophical Transactions of the Royal Society of London. Biological Sciences. 360, 1462, p. 1969-1974Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A method for detecting IBD regions simultaneously in multiple individuals--with applications to disease genetics
Moltke, Ida, Albrechtsen, Anders, Hansen, Thomas van Overeem, Nielsen, Finn Cilius & Nielsen, Rasmus, 2011, In: Genome Research. 21, 7, p. 1168-80 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
A population phylogenetic view of mitochondrial heteroplasmy
Wilton, P. R., Zaidi, A., Makova, K. & Nielsen, Rasmus, 2018, In: Genetics. 208, 3, p. 1261-1274 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A recent bottleneck of Y chromosome diversity coincides with a global change in culture
Karmin, M., Saag, L., Vicente, M., Wilson Sayres, M. A., Järve, M., Talas, U. G., Rootsi, S., Ilumäe, A-M., Mägi, R., Mitt, M., Pagani, L., Puurand, T., Faltyskova, Z., Clemente, F., Cardona, A., Metspalu, E., Sahakyan, H., Yunusbayev, B., Hudjashov, G., DeGiorgio, M. & 80 others, , 2015, In: Genome Research. 25, 4, p. 459-466 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
A scan for human-specific relaxation of negative selection reveals unexpected Polymorphism in Proteasome Genes
Somel, M., Sayres, M. A. W., Jordan, G., Huerta-Sanchez, E., Fumagalli, M., Ferrer-Admetlla, A. & Nielsen, Rasmus, 2013, In: Molecular Biology and Evolution. 30, 8, p. 1808-1815 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ANGSD: analysis of next generation sequencing data
Korneliussen, Thorfinn Sand, Albrechtsen, Anders & Nielsen, Rasmus, 2014, In: B M C Bioinformatics. 15, 13 p., 356.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adaptionism-30 years after Gould and Lewontin
Nielsen, Rasmus, 2009, In: Evolution. 63, 10, p. 2487-90 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Adaptive evolution of cytochrome c oxidase: Infrastructure for a carnivorous plant radiation
Jobson, R. W., Nielsen, Rasmus, Laakkonen, L., Wikström, M. & Albert, V. A., 2004, In: Proceedings of the National Academy of Sciences of the United States of America. 101, 52, p. 18064-18068 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adaptive genic evolution in the Drosophila genomes
Shapiro, J. A., Huang, W., Zhang, C., Hubisz, M. J., Lu, J., Turissini, D. A., Fang, S., Wang, H., Hudson, R. R., Nielsen, Rasmus, Chen, Z. & Wu, C., 2007, In: Proceedings of the National Academy of Science of the United States of America. 104, 7, p. 2271-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNA
Huerta-Sanchez, E., Jin, X., Asan, Bianba, Z., Peter, B. M., Vinckenbosch, N., Liang, Y., Yi, X., He, M., Somel, M., Ni, P., Wang, B., Ou, X., Huasang, Luosang, J., Cuo, Z. X. P., Li, K., Gao, G., Yin, Y., Wang, W. & 7 others, , 2014, In: Nature. 512, 7513, p. 194-197 4 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
An Aboriginal Australian genome reveals separate human dispersals into Asia
Rasmussen, M., Guo, X., Wang, Y., Lohmueller, K. E., Rasmussen, S., Albrechtsen, A., Skotte, L., Lindgreen, S., Metspalu, M., Jombart, T., Kivisild, T., Zhai, W., Eriksson, A., Manica, A., Orlando, L., De La Vega, F. M., Tridico, S., Metspalu, E., Nielsen, K., Avila Arcos, M. D. C. & 38 others, , 2011, In: Science. 334, 6052, p. 94-98 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
An approximate full-likelihood method for inferring selection and allele frequency trajectories from DNA sequence data
Stern, A. J., Wilton, P. R. & Nielsen, Rasmus, 2019, In: PLOS Genetics. 15, 9, 32 p., e1008384.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An increase in [Ca2+]i activates basolateral chloride channels and inhibits apical sodium channels in frog skin epithelium
Larsen, Birger Brodin, Rytved, K. A. & Nielsen, Rasmus, 1996, In: Pflügers Archiv - European Journal of Physiology. 433, 1-2, p. 16-25 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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An investigation of the statistical power of neutrality tests based on comparative and population genetic data
Zhai, W., Nielsen, Rasmus & Slatkin, M., 2009, In: Molecular Biology and Evolution. 26, 2, p. 273-83 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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AncestralClust: clustering of divergent nucleotide sequences by ancestral sequence reconstruction using phylogenetic trees
Pipes, L. & Nielsen, Rasmus, 2022, In: Bioinformatics. 38, 3, p. 663-670 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancient DNA reveals late survival of mammoth and horse in interior Alaska
Haile, James Seymour, Froese, D. G., Macphee, R. D. E., Roberts, R. G., Arnold, L. J., Reyes, A. V., Rasmussen, M., Nielsen, Rasmus, Brook, B. W., Robinson, S., Demuro, M., Gilbert, M Thomas P, Munch, K., Austin, J. J., Cooper, A., Barnes, I., Möller, P. & Willerslev, Eske, 2009, In: Proceedings of the National Academy of Science of the United States of America. 106, 52, p. 22352-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancient Hybridization with an Unknown Population Facilitated High-Altitude Adaptation of Canids
Wang, M., Wang, S., Li, Y., Jhala, Y., Thakur, M., Otecko, N. O., Si, J., Chen, H., Shapiro, B., Nielsen, Rasmus, Zhang, Y., Wu, D. & Parsch, J. (ed.), 2020, In: MOLECULAR BIOLOGY AND EVOLUTION . 37, 9, p. 2616-2629Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancient bacteria show evidence of DNA repair.
Johnson, S. S., Hebsgaard, M. B., Christensen, T. R., Mastepanov, M., Nielsen, Rasmus, Munch, K., Brand, T., Gilbert, M Thomas P, Zuber, M. T., Bunce, M., Rønn, Regin, Gilichinsky, D., Froese, D. & Willerslev, Eske, 2007, In: Proceedings of the National Academy of Science of the United States of America. 104, 36, p. 14401-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancient biomolecules from deep ice cores reveal a forested southern Greenland.
Willerslev, E., Cappellini, E., Boomsma, W. K., Nielsen, R., Hebsgaard, M. B., Brand, T. B., Hofreiter, M., Bunce, M., Poinar, H. N., Dahl-Jensen, D., Johnsen, S. J., Steffensen, J. P., Bennike, O., Schwenninger, J-L., Nathan, R., Armitage, S., de Hoog, C-J., Alfimov, V., Christl, M., Beer, J. & 10 others, , 2007, In: Science. 317, 5834, p. 111-114 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancient genomes show social and reproductive behavior of early Upper Paleolithic foragers
Sikora, M., Seguin-Orlando, A., Sousa, V. C., Albrechtsen, A., Korneliussen, T. S., Ko, A., Rasmussen, S., Dupanloup, I., Nigst, P. R., Bosch, M. D., Renaud, G., Allentoft, M. E., Margaryan, A., Vasilyev, S. V., Veselovskaya, E. V., Borutskaya, S. B., Deviese, T., Comeskey, D., Higham, T., Manica, A. & 7 others, , 3 Nov 2017, In: Science. 358, 6363, p. 659-662 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ancient human genome sequence of an extinct Palaeo-Eskimo
Rasmussen, M., Li, Y., Lindgreen, S., Pedersen, J. S., Albrechtsen, A., Moltke, I., Metspalu, M., Metspalu, E., Kivisild, T., Gupta, R., Bertalan, M., Nielsen, K., Gilbert, T., Wang, Y., Raghavan, M., Campos, P., Kamp, H. L. M., Wilson, A. S., Gledhill, A., Tridico, S. & 32 others, , 11 Feb 2010, In: Nature. 463, 7282, p. 757-762 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Archaic adaptive introgression in TBX15/WARS2
Racimo, Fernando, Gokhman, D., Fumagalli, M., Ko, A., Hansen, Torben, Moltke, Ida, Albrechtsen, Anders, Carmel, L., Huerta-Sánchez, E. & Nielsen, Rasmus, 2017, In: Molecular Biology and Evolution. 34, 3, p. 509-524 16 p., msw283.Research output: Contribution to journal › Journal article › Research › peer-review
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Ascertainment bias in studies of human genome-wide polymorphism
Clark, A. G., Hubisz, M. J., Bustamente, C. D., Williamson, S. H. & Nielsen, Rasmus, 2005, In: Genome Research. 15, 11, p. 1496-1502Research output: Contribution to journal › Journal article › Research › peer-review
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Assessing Uncertainty in the Rooting of the SARS-CoV-2 Phylogeny
Pipes, L., Wang, H., Huelsenbeck, J. P. & Nielsen, Rasmus, 2021, In: Molecular Biology and Evolution. 38, 4, p. 1537-1543 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assessing the evolutionary impact of amino acid mutations in the human genome
Boyko, A. R., Williamson, S. H., Indap, A. R., Degenhardt, J. D., Hernandez, R. D., Lohmueller, K. E., Adams, M. D., Schmidt, S., Sninsky, J. J., Sunyaev, S. R., White, T. J., Nielsen, Rasmus, Clark, A. G. & Bustamante, C. D., 2008, In: PLoS Genetics. 4, 5, p. e1000083Research output: Contribution to journal › Journal article › Research › peer-review
Association mapping for compound heterozygous traits using phenotypic distance and integer programming
Gusfield, D. & Nielsen, Rasmus, 1 Jan 2015, Algorithms in Bioinformatics - 15th International Workshop, WABI 2015, Proceedings. Pop, M. & Touzet, H. (eds.). Springer Verlag, p. 136-147 12 p. A1. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), Vol. 9289).Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
- Published
Bacterial natural transformation by highly fragmented and damaged DNA
Overballe-Petersen, S., Harms, K., Orlando, L. A. A., Moreno Mayar, J. Víctor, Rasmussen, Simon, Dahl, Tais Wittchen, Rosing, Minik Thorleif, Poole, A. M., Sicheritz-Ponten, T., Brunak, S., Inselmann, S., de Vries, J., Wackernagel, W., Pybus, O. G., Nielsen, Rasmus, Johnsen, P. J., Nielsen, K. M. & Willerslev, Eske, 3 Dec 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 49, p. 19860–19865 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Balancing Selection Maintains a Form of ERAP2 that Undergoes Nonsense-Mediated Decay and Affects Antigen Presentation
Andrés, A. M., Dennis, M. Y., Kretzschmar, W. W., Cannons, J. L., Lee-Lin, S., Hurle, B., Schwartzberg, P. L., Williamson, S. H., Bustamante, C. D., Nielsen, Rasmus, Clark, A. G. & Green, E. D., 2010, In: PLOS Genetics. 6, 10, 13 p., e1001157.Research output: Contribution to journal › Journal article › Research › peer-review
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Bayes Empirical Bayes Inference of Amino Acid Sites Under Positive Selection
Yang, Z., Wong, W. S. W. & Nielsen, Rasmus, 2005, In: Molecular Biology and Evolution. 22, 4, p. 1107-1118Research output: Contribution to journal › Journal article › Research › peer-review
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Bayesian and maximum likelihood estimation of genetic maps
York, T. L., Durrett, R. T., Tanksley, S. & Nielsen, Rasmus, 2005, In: Genetics Research. 85, 2, p. 159-168Research output: Contribution to journal › Journal article › Research › peer-review
Bayesian estimation of the number of inversions in the history of two chromosomes
York, T. L., Durrett, R. & Nielsen, Rasmus, 1 Dec 2002, In: Journal of Computational Biology. 9, 6, p. 805-818 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bayesian inference of admixture graphs on Native American and Arctic populations
Nielsen, S. V., Vaughn, Andrew Howland, Leppälä, K., Landis, M. J., Mailund, T. & Nielsen, Rasmus, 2023, In: PLOS Genetics. 19, 2, 22 p., e1010410.Research output: Contribution to journal › Journal article › Research › peer-review
Bottleneck and selection in the germline and maternal age influence transmission of mitochondrial DNA in human pedigrees
Zaidi, A. A., Wilton, P. R., Su, M. S., Paul, I. M., Arbeithuber, B., Anthony, K., Nekrutenko, A., Nielsen, Rasmus & Makova, K. D., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 50, p. 25172-25178 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CCR5-Delta 32 is deleterious in the homozygous state in humans
Wei, X. & Nielsen, Rasmus, Jun 2019, In: Nature Medicine. 25, 6, p. 909-910Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Calculation of Tajima's D and other neutrality test statistics from low depth next-generation sequencing data
Korneliussen, Thorfinn Sand, Moltke, Ida, Albrechtsen, Anders & Nielsen, Rasmus, 2013, In: B M C Bioinformatics. 14, 14 p., 289.Research output: Contribution to journal › Journal article › Research › peer-review
Changes in ds/dn in the HIV-1 env Gene
Nielsen, Rasmus, 1999, In: MOLECULAR BIOLOGY AND EVOLUTION . 16, 5, p. 711-714 4 p.Research output: Contribution to journal › Letter › Research › peer-review
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Characteristics of the tomato nuclear genome as determined by sequencing undermethylated EcoRI digested fragments
Wang, Y., van der Hoeven, R. S., Nielsen, Rasmus, Mueller, L. A. & Tanksley, S. D., 2005, In: Theoretical and Applied Genetics. 112, 1, p. 72-84Research output: Contribution to journal › Journal article › Research › peer-review
Classic Selective Sweeps Revealed by Massive Sequencing in Cattle
Qanbari, S., Pausch, H., Jansen, S., Somel, M., Strom, T. M., Fries, R., Nielsen, Rasmus & Simianer, H., 2014, In: PLOS Genetics. 10, 2, 13 p., e1004148.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative genome sequencing of Drosophila pseudoobscura: Chromosomal, gene, and cis-element evolution
Richards, S., Liu, Y., Bettencourt, B. R., Hradecky, P., Letovsky, S., Nielsen, Rasmus & et al., 2005, In: Genome Research. 15, 1, p. 1-18Research output: Contribution to journal › Journal article › Research › peer-review
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Comparative genomics: Difference of expression
Nielsen, Rasmus, 2006, In: Nature. 440, 7081, p. 161-161Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complete resequencing of 40 genomes reveals domestication events and genes in silkworm (Bombyx)
Xia, Q., Guo, Y., Zhang, Z., Li, D., Xuan, Z., Li, Z., Dai, F., Li, Y., Cheng, D., Li, R., Cheng, T., Jiang, T., Becquet, C., Xu, X., Liu, C., Zha, X., Fan, W., Lin, Y., Shen, Y., Jiang, L. & 38 others, , 2009, In: Science. 326, 5951, p. 433-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Composite likelihood method for inferring local pedigrees
Ko, A. & Nielsen, Rasmus, 21 Aug 2017, In: PLoS Genetics. 13, 8, 21 p., e1006963.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Convergent evolution of increased urine-concentrating ability in desert mammals
Rocha, J. L., Brito, J. C., Nielsen, Rasmus & Godinho, R., 2021, In: Mammal Review. 51, 4, p. 482-491 10 p.Research output: Contribution to journal › Review › Research › peer-review
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Correcting estimators of theta and Tajima's D for ascertainment biases caused by the single-nucleotide polymorphism discovery process
Ramírez-Soriano, A. & Nielsen, Rasmus, 2009, In: Genetics. 181, 2, p. 701-10 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Correcting for ascertainment biases when analyzing SNP data: applications to the estimation of linkage disequilibrium
Nielsen, Rasmus & Signorovitch, J., 2003, In: Theoretical Population Biology. 63, 3, p. 245-255 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Costs and benefits of mutational robustness in RNA viruses
Stern, A., Bianco, S., Yeh, M. T., Wright, C., Butcher, K., Tang, C., Nielsen, Rasmus & Andino, R., 2014, In: Cell Reports. 8, 4, p. 1026-1036 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Covariance of pairwise differences on a multi-species coalescent tree and implications for FST
Guerra, G. & Nielsen, Rasmus, 2022, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 377, 1852, 14 p., 20200415.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CpG + CpNpG Analysis of Protein-Coding Sequences from Tomato
Hobolth, A., Nielsen, Rasmus, Wang, Y., Wu, F. & Tanksley, S. D., 2006, In: Molecular Biology and Evolution. 23, 6, p. 1318-1323Research output: Contribution to journal › Journal article › Research › peer-review
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Darwinian and demographic forces affecting human protein coding genes.
Nielsen, Rasmus, Hubisz, M. J., Hellmann, I., Torgerson, D., Andres, A. M., Albrechtsen, Anders, Gutenkunst, R., Adams, M. D., Cargill, M., Boyko, A., Indap, A., Bustamante, C. D. & Clark, A. G., 2009, In: Genome Research. 19, 5, p. 838-49 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Demographic histories and patterns of linkage disequilibrium in Chinese and Indian rhesus macaques
Hernandez, R. D., Hubisz, M. J., Wheeler, D. A., Smith, D. G., Ferguson, B., Rogers, J., Nazareth, L., Indap, A., Bourquin, T., McPherson, J., Muzny, D., Gibbs, R., Nielsen, Rasmus & Bustamante, C. D., 2007, In: Science. 316, 5822, p. 240-3 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dependence of paracentric inversion rate on tract length
York, T. L., Durrett, R. & Nielsen, Rasmus, 2007, In: BMC Bioinformatics. 8, p. 115Research output: Contribution to journal › Journal article › Research › peer-review
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Design of association studies with pooled or un-pooled next-generation sequencing data
Kim, S. Y., Li, Y., Guo, Y., Li, R., Holmkvist, J., Hansen, Torben, Pedersen, Oluf Borbye, Wang, J. & Nielsen, Rasmus, 2010, In: Genetic Epidemiology. 34, 5, p. 479-491 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Detecting Selection in Multiple Populations by Modeling Ancestral Admixture Components
Cheng, J. Y., Stern, A. J., Racimo, Fernando & Nielsen, Rasmus, 2022, In: Molecular Biology and Evolution. 39, 1, 14 p., msab294.Research output: Contribution to journal › Journal article › Research › peer-review
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Detecting Site-Specific Physicochemical Selective Pressures: Applications to the Class I HLA of the Human Major Histocompatibility Complex and the SRK of the Plant Sporophytic Self-Incompatibility System
Sainudiin, R., Wong, W. S. W., Yogeeswaran, K., Nasrallah, J. B., Yang, Z. & Nielsen, Rasmus, 2005, In: Journal of Molecular Evolution. 60, 3, p. 315-326Research output: Contribution to journal › Journal article › Research › peer-review
Detecting adaptive trait loci in nonmodel systems: divergence or admixture mapping?
Crawford, J. E. & Nielsen, Rasmus, 2013, In: Molecular Ecology. 22, 24, p. 6131-6148 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detecting coevolving amino acid sites using Bayesian mutational mapping
Dimmic, M. W., Hubisz, M. J., Bustamente, C. D. & Nielsen, Rasmus, 2005, In: Bioinformatics. 21, 1, p. i126-i135Research output: Contribution to journal › Journal article › Research › peer-review
Detecting recent selective sweeps while controlling for mutation rate and background selection
Huber, C. D., DeGiorgio, M., Hellmann, I. & Nielsen, Rasmus, 2016, In: Molecular Ecology. 25, 1, p. 142-156 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detecting selection needs comparative data
Nielsen, Rasmus & Hubisz, M. J., 2005, In: Nature. 433, 7023, p. E6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disclosure of variation
Nielsen, Rasmus, 2005, In: Nature. 434, 7031, p. 288-289Research output: Contribution to journal › Journal article › Research › peer-review
Disentangling selection on genetically correlated polygenic traits via whole-genome genealogies
Stern, A. J., Speidel, L., Zaitlen, N. A. & Nielsen, Rasmus, 2021, In: American Journal of Human Genetics. 108, 2, p. 219-239 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DistAngsd: Fast and Accurate Inference of Genetic Distances for Next-Generation Sequencing Data
Zhao, Lei, Nielsen, Rasmus & Korneliussen, Thorfinn Sand, 2022, In: Molecular Biology and Evolution. 39, 6, 14 p., msac119.Research output: Contribution to journal › Journal article › Research › peer-review
Distinguishing Migration From Isolation: A Markov Chain Monte Carlo Approach
Nielsen, Rasmus & Wakeley, J., 2001, In: Genetics. 158, 2, p. 885-896 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Distinguishing between Selective Sweeps from Standing Variation and from a De Novo Mutation
Peter, B. M., Huerta-Sanchez, E. & Nielsen, Rasmus, 2012, In: P L o S Genetics (Online). 8, 10, p. 1-14 14 p., e1003011.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Divergence, gene flow, and the origin of leapfrog geographic distributions: The history of colour pattern variation in Phyllobates poison-dart frogs
Márquez, R., Linderoth, T. P., Mejia-Vargas, D., Nielsen, Rasmus, Amezquita, A. & Kronforst, M. R., 2020, In: Molecular Ecology. 29, 19, p. 3702-3719 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early human dispersals within the Americas
Moreno-Mayar, J. V., Vinner, L., de Barros Damgaard, P., de la Fuente, C., Allentoft, M. E., Vimala, T., Racimo, F., Rasmussen, S., Margaryan, A., Iraeta Orbegozo, M., Mylopotamitaki, D., Alexandersen, V., Primeau, C., Gregersen, K., Hansen, K. L., Lynnerup, N., Kjær, K., Schroeder, H., Malaspinas, A. S., Sikora, M. & 2 others, , 7 Dec 2018, In: Science (New York, N.Y.). 362, 6419, p. 1, 1-11 12 p., eaav2621.Research output: Contribution to journal › Journal article › Research › peer-review
Effect of nonindependent substitution on phylogenetic accuracy
Huelsenbeck, J. P. & Nielsen, Rasmus, 1999, In: Systematic Biology. 48, 2, p. 317-328 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elevated genetic risk for multiple sclerosis emerged in steppe pastoralist populations
Barrie, W., Yang, Y., Irving-Pease, E. K., Attfield, K. E., Scorrano, G., Jensen, L. T., Armen, A. P., Dimopoulos, E. A., Stern, A., Refoyo-Martinez, A., Pearson, A., Ramsøe, A., Gaunitz, C., Demeter, F., Jørkov, M. L. S., Møller, S. B., Springborg, B., Klassen, L., Hyldgård, I. M., Wickmann, N. & 11 others, , 2024, In: Nature. 625, 7994, p. 321-328Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Emergence and Spread of Basal Lineages of Yersinia pestis during the Neolithic Decline
Rascovan, N., Sjogren, K., Kristiansen, K., Nielsen, Rasmus, Willerslev, Eske, Desnues, C. & Rasmussen, Simon, 2019, In: Cell. 176, 1-2, p. 295-305.e10Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Error-prone polymerase activity causes multinucleotide mutations in humans
Harris, K. & Nielsen, Rasmus, 1 Sep 2014, In: Genome Research. 24, 9, p. 1445-1454 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimating IBD tracts from low coverage NGS data
Vieira, Filipe Garrett, Albrechtsen, Anders & Nielsen, Rasmus, 2016, In: Bioinformatics. 32, 14, p. 2096-2102 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimating inbreeding coefficients from NGS data: impact on genotype calling and allele frequency estimation
Vieira, Filipe Garrett, Fumagalli, M., Albrechtsen, Anders & Nielsen, Rasmus, 2013, In: Genome Research. 23, p. 1852-1861 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Estimating population divergence time and phylogeny from single-nucleotide polymorphisms data with outgroup ascertainment bias
Wang, Y. & Nielsen, Rasmus, 2012, In: Molecular Ecology. 21, 4, p. 974-986 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimating the relative proportions of SARS-CoV-2 haplotypes from wastewater samples
Pipes, L., Chen, Z., Afanaseva, S. & Nielsen, Rasmus, 2022, In: Cell Reports Methods. 2, 10, 100313.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimating the timing of multiple admixture events using 3-locus linkage disequilibrium
Liang, M., Shishkin, M., Mikhailova, A., Shchur, V. & Nielsen, Rasmus, 2022, In: PLOS Genetics. 18, 7, 17 p., e1010281.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimating the timing of multiple admixture pulses during local ancestry inference
Medina, P., Thornlow, B., Nielsen, Rasmus & Corbett-Detig, R., 2018, In: Genetics. 210, 3, p. 1089-1107 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimation of 2N(e)s from temporal allele frequency data
Bollback, J. P., York, T. L. & Nielsen, Rasmus, 2008, In: Genetics. 179, p. 497-502 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimation of allele frequency and association mapping using next-generation sequencing data
Kim, S. Y., Lohmueller, K. E., Albrechtsen, Anders, Li, Y., Korneliussen, Thorfinn Sand, Tian, G., Grarup, Niels, Jiang, T., Andersen, G., Witte, D., Jorgensen, T., Hansen, Torben, Pedersen, Oluf Borbye, Wang, J. & Nielsen, Rasmus, 2011, In: B M C Bioinformatics. 12, p. 231 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of an Improved Branch-Site Likelihood Method for Detecting Positive Selection at the Molecular Level
Zhang, J., Nielsen, Rasmus & Yang, Z., 2005, In: Molecular Biology and Evolution. 22, 12, p. 2472-2479Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of methods for estimating coalescence times using ancestral recombination graphs
Y C Brandt, D., Wei, X., Deng, Y., Vaughn, A. H. & Nielsen, Rasmus, 2022, In: Genetics. 221, 1, 13 p., iyac044.Research output: Contribution to journal › Journal article › Research › peer-review
Evidence for Positive Selection on a Number of MicroRNA Regulatory Interactions during Recent Human Evolution
Li, J., Liu, Y., Xin, X., Kim, T. S., Cabeza, E. A., Ren, J., Nielsen, Rasmus, Wrana, J. L. & Zhang, Z., 1 Mar 2012, In: P L o S Genetics (Online). 8, 3Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence for a Na+/Ca2+ exchange mechanism in frog skin epithelium
Madsen, K. H., Larsen, Birger Brodin & Nielsen, Rasmus, 1999, In: Pflügers Archiv - European Journal of Physiology. 437, 2, p. 175-81 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Evidence for archaic adaptive introgression in humans
Racimo, Fernando, Sankararaman, S., Nielsen, Rasmus & Huerta-Sánchez, E., 18 May 2015, In: Nature Reviews Genetics. 16, 6, p. 359-371 13 p.Research output: Contribution to journal › Review › Research › peer-review
Evolution of GOUNDRY, a cryptic subgroup of Anopheles gambiae s.l., and its impact on susceptibility to Plasmodium infection
Crawford, J. E., Riehle, M. M., Markianos, K., Bischoff, E., Guelbeogo, W. M., Gneme, A., Sagnon, N., Vernick, K. D., Nielsen, Rasmus & Lazzaro, B. P., 2016, In: Molecular Ecology. 25, 7, p. 1494-1510 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evolution of genes and genomes on the Drosophila phylogeny. Drosophila 12 Genomes Consortium
Clark, A. G., Eisen, M. B., Smith, D. R., Bergman, C. M., Oliver, B., Markow, T. A., Kaufman, T. C., Kellis, M., Gelbart, W., Iyer, V. N., Pollard, D. A., Sackton, T. B., Larracuente, A. M., Singh, N. D., Abad, J. P., Abt, D. N., Adryan, B., Aguade, M., Akashi, H., Anderson, W. W. & 31 others, , 2007, In: Nature. 450, 7167, p. 203-18 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evolutionary and biomedical insights from the rhesus macaque genome
Gibbs, R. A., Rogers, J., Katze, M. G., Bumgarner, R., Weinstock, G. M., Mardis, E. R., Remington, K. A., Strausberg, R. L., Venter, J. C., Wilson, R. K., Batzer, M. A., Bustamante, C. D., Eichler, E. E., Hahn, M. W., Hardison, R. C., Makova, K. D., Miller, W., Milosavljevic, A., Palermo, R. E., Siepel, A. & 31 others, , 2007, In: Science. 316, 5822, p. 222-34 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes
Albrechtsen, A., Grarup, N., Li, Y., Sparsø, T. H., Tian, G., Cao, H., Jiang, T., Kim, S. Y., Korneliussen, T. S., Li, Q., Nie, C., Wu, R., Skotte, L., Morris, A. P., Ladenvall, C., Cauchi, S., Stancáková, A., Andersen, G., Astrup, A., Banasik, K. & 86 others, , 2013, In: Diabetologia. 56, 2, p. 298-310 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploring variation in the d(N)/d(S) ratio among sites and lineages using mutational mappings: applications to the influenza virus
Zhai, W., Slatkin, M. & Nielsen, Rasmus, 2007, In: Journal of Molecular Evolution. 65, 3, p. 340-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 3311
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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SNP calling, genotype calling, and sample allele frequency estimation from new-generation sequencing data
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