Rasmus Nielsen
Professor
Section for Geogenetics
Øster Voldgade 5-7, 1350 København K
Section for Geogenetics
Øster Voldgade 5-7
1350 København K
- 2011
- Published
Estimation of allele frequency and association mapping using next-generation sequencing data
Kim, S. Y., Lohmueller, K. E., Albrechtsen, Anders, Li, Y., Korneliussen, Thorfinn Sand, Tian, G., Grarup, Niels, Jiang, T., Andersen, G., Witte, D., Jorgensen, T., Hansen, Torben, Pedersen, Oluf Borbye, Wang, J. & Nielsen, Rasmus, 2011, In: B M C Bioinformatics. 12, p. 231 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques
Yan, G., Zhang, G., Fang, X., Zhang, Y., Li, C., Ling, F., Cooper, D. N., Li, Q., Li, Y., van Gool, A. J., Du, H., Chen, J., Chen, R., Zhang, P., Huang, Z., Thompson, J. R., Meng, Y., Bai, Y., Wang, J., Zhuo, M. & 26 others, , 2011, In: Nature Biotechnology. 29, 11, p. 1019-1023 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Genotype and SNP calling from next-generation sequencing data
Nielsen, Rasmus, Paul, J. S., Albrechtsen, Anders & Song, Y. S., 2011, In: Nature Reviews. Genetics. 12, 6, p. 443-451 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
Lohmueller, K. E., Albrechtsen, Anders, Li, Y., Kim, S. Y., Korneliussen, Thorfinn Sand, Vinckenbosch, N., Tian, G., Huerta-Sanchez, E., Feder, A. F., Grarup, Niels, Jørgensen, T., Jiang, T., Witte, D. R., Sandbæk, A., Hellmann, I., Lauritzen, T., Hansen, Torben, Pedersen, Oluf Borbye, Wang, J. & Nielsen, Rasmus, 2011, In: P L o S Genetics. 7, 10, 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Species-specific responses of Late Quaternary megafauna to climate and humans
Lorenzen, E., Nogues, D. B., Orlando, L. A. A., Weinstock Arenovitz, J., Binladen, J. K. M. A., Marske, K. A., Ugan, A., Borregaard, M. K., Gilbert, M. T. P., Nielsen, R., Ho, S. Y. W., Goebel, T., Graf, K. E., Byers, D., Stenderup, J., Rasmussen, M., Campos, P., Leonard, J. A., Koepfli, K-P., Froese, D. & 35 others, , 2011, In: Nature. 479, 7373, p. 359-364 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Sequencing of 50 human exomes reveals adaptation to high altitude
Yi, X., Liang, Y., Huerta-Sanchez, E., Jin, X., Cuo, Z. X. P., Pool, J. E., Xu, X., Jiang, H., Vinckenbosch, N., Korneliussen, T. S., Zheng, H., Liu, T., He, W., Li, K., Luo, R., Nie, X., Wu, H., Zhao, M., Cao, H., Zou, J. & 50 others, , 2 Jul 2010, In: Science. 329, 5987, p. 75-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancient human genome sequence of an extinct Palaeo-Eskimo
Rasmussen, M., Li, Y., Lindgreen, S., Pedersen, J. S., Albrechtsen, A., Moltke, I., Metspalu, M., Metspalu, E., Kivisild, T., Gupta, R., Bertalan, M., Nielsen, K., Gilbert, T., Wang, Y., Raghavan, M., Campos, P., Kamp, H. L. M., Wilson, A. S., Gledhill, A., Tridico, S. & 32 others, , 11 Feb 2010, In: Nature. 463, 7282, p. 757-762 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
A draft sequence of the neandertal genome
Green, R. E., Krause, J., Briggs, A. W., Maricic, T., Stenzel, U., Kircher, M., Patterson, N., Li, H., Zhai, W., Fritz, M. H. Y., Hansen, N. F., Durand, E. Y., Malaspinas, A-S., Jensen, J. D., Marques-Bonet, T., Alkan, C., Prüfer, K., Meyer, M., Burbano, H. A., Good, J. M. & 36 others, , 2010, In: Science. 328, 5979, p. 710-722 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Balancing Selection Maintains a Form of ERAP2 that Undergoes Nonsense-Mediated Decay and Affects Antigen Presentation
Andrés, A. M., Dennis, M. Y., Kretzschmar, W. W., Cannons, J. L., Lee-Lin, S., Hurle, B., Schwartzberg, P. L., Williamson, S. H., Bustamante, C. D., Nielsen, Rasmus, Clark, A. G. & Green, E. D., 2010, In: PLOS Genetics. 6, 10, 13 p., e1001157.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design of association studies with pooled or un-pooled next-generation sequencing data
Kim, S. Y., Li, Y., Guo, Y., Li, R., Holmkvist, J., Hansen, Torben, Pedersen, Oluf Borbye, Wang, J. & Nielsen, Rasmus, 2010, In: Genetic Epidemiology. 34, 5, p. 479-491 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
In defence of model-based inference in phylogeography
Beaumont, M. A., Nielsen, R., Robert, C., Hey, J., Gaggiotti, O., Knowles, L., Estoup, A., Panchal, M., Corander, J., Hickerson, M., Sisson, S. A., Fagundes, N., Chikhi, L., Beerli, P., Vitalis, R., Cornuet, J. M., Huelsenbeck, J., Foll, M., Yang, Z., Rousset, F. & 2 others, , 2010, In: Molecular Ecology. 19, 3, p. 436-446 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Natural selection and the distribution of identity-by-descent in the human genome
Albrechtsen, Anders, Moltke, Ida & Nielsen, Rasmus, 2010, In: Genetics. 186, 1, p. 295-308 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Positive selection on apoptosis related genes
Rodrigues da Fonseca, Rute Andreia, Kosiol, C., Vinař, T., Siepel, A. & Nielsen, Rasmus, 2010, In: FEBS Letters. 584, 3, p. 469-476 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants
Li, Y., Vinckenbosch, N., Tian, G., Huerta-Sanchez, E., Jiang, T., Jiang, H., Albrechtsen, A., Andersen, G., Cao, H., Korneliussen, T. S., Grarup, N., Guo, Y., Hellman, I., Jin, X., Li, Q., Liu, J., Liu, X., Sparsø, T., Tang, M., Wu, H. & 18 others, , 2010, In: Nature Genetics. 42, 11, p. 969-72 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The sequence and de novo assembly of the giant panda genome
Li, R., Fan, W., Tian, G., Zhu, H., He, L., Cai, J., Huang, Q., Cai, Q., Li, B., Bai, Y., Zhang, Z., Zhang, Y., Wang, W., Li, J., Wei, F., Li, H., Jian, M., Li, J., Zhang, Z., Nielsen, R. & 103 others, , 2010, In: Nature. 463, 7279, p. 311-317 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Adaptionism-30 years after Gould and Lewontin
Nielsen, Rasmus, 2009, In: Evolution. 63, 10, p. 2487-90 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An investigation of the statistical power of neutrality tests based on comparative and population genetic data
Zhai, W., Nielsen, Rasmus & Slatkin, M., 2009, In: Molecular Biology and Evolution. 26, 2, p. 273-83 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancient DNA reveals late survival of mammoth and horse in interior Alaska
Haile, James Seymour, Froese, D. G., Macphee, R. D. E., Roberts, R. G., Arnold, L. J., Reyes, A. V., Rasmussen, M., Nielsen, Rasmus, Brook, B. W., Robinson, S., Demuro, M., Gilbert, M Thomas P, Munch, K., Austin, J. J., Cooper, A., Barnes, I., Möller, P. & Willerslev, Eske, 2009, In: Proceedings of the National Academy of Science of the United States of America. 106, 52, p. 22352-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complete resequencing of 40 genomes reveals domestication events and genes in silkworm (Bombyx)
Xia, Q., Guo, Y., Zhang, Z., Li, D., Xuan, Z., Li, Z., Dai, F., Li, Y., Cheng, D., Li, R., Cheng, T., Jiang, T., Becquet, C., Xu, X., Liu, C., Zha, X., Fan, W., Lin, Y., Shen, Y., Jiang, L. & 38 others, , 2009, In: Science. 326, 5951, p. 433-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Correcting estimators of theta and Tajima's D for ascertainment biases caused by the single-nucleotide polymorphism discovery process
Ramírez-Soriano, A. & Nielsen, Rasmus, 2009, In: Genetics. 181, 2, p. 701-10 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Darwinian and demographic forces affecting human protein coding genes.
Nielsen, Rasmus, Hubisz, M. J., Hellmann, I., Torgerson, D., Andres, A. M., Albrechtsen, Anders, Gutenkunst, R., Adams, M. D., Cargill, M., Boyko, A., Indap, A., Bustamante, C. D. & Clark, A. G., 2009, In: Genome Research. 19, 5, p. 838-49 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In defense of statistical methods for detecting positive selection
Yang, Z., Nielsen, Rasmus & Goldman, N., 2009, In: Proceedings of the National Academy of Science of the United States of America. 106, 36, p. E95Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inference of historical changes in migration rate from the lengths of migrant tracts
Pool, J. E. & Nielsen, Rasmus, 2009, In: Genetics. 181, 2, p. 711-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Radiation of extant Cetaceans Driven by Restructuring of the Oceans
Steeman, M. E., Hebsgaard, M. B., Fordyce, J., Syw, H., Rabovsky, D., Nielsen, Rasmus, Rahbek, Carsten, Glenner, Henrik, Sørensen, Martin Vinther & Willerslev, Eske, 2009, In: Systematic Biology. 58, p. 573-585 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Relatedness mapping and tracts of relatedness for genome-wide data in the presence of linkage disequilibrium
Albrechtsen, Anders, Korneliussen, Thorfinn Sand, Moltke, Ida, van Overseem Hansen, T., Nielsen, Finn Cilius & Nielsen, Rasmus, 2009, In: Genetic Epidemiology. 33, 3, p. 266-274Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Statistical inferences in phylogeography
Nielsen, Rasmus & Beaumont, M. A., 2009, In: Molecular Ecology. 18, 6, p. 1034-47 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targets of balancing selection in the human genome
Andrés, A. M., Hubisz, M. J., Indap, A., Torgerson, D. G., Degenhardt, J. D., Boyko, A. R., Gutenkunst, R. N., White, T. J., Green, E. D., Bustamante, C. D., Clark, A. G. & Nielsen, Rasmus, 2009, In: Molecular Biology and Evolution. 26, 12, p. 2755-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Assessing the evolutionary impact of amino acid mutations in the human genome
Boyko, A. R., Williamson, S. H., Indap, A. R., Degenhardt, J. D., Hernandez, R. D., Lohmueller, K. E., Adams, M. D., Schmidt, S., Sninsky, J. J., Sunyaev, S. R., White, T. J., Nielsen, Rasmus, Clark, A. G. & Bustamante, C. D., 2008, In: PLoS Genetics. 4, 5, p. e1000083Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimation of 2N(e)s from temporal allele frequency data
Bollback, J. P., York, T. L. & Nielsen, Rasmus, 2008, In: Genetics. 179, p. 497-502 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fast phylogenetic DNA barcoding
Terkelsen, K. M., Boomsma, Wouter, Willerslev, Eske & Nielsen, Rasmus, 2008, In: Philosophical Transactions of the Royal Society of London. Biological Sciences. 363, 1512, p. 3997-4002 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutation-selection models of codon substitution and their use to estimate selective strengths on codon usage
Yang, Z. & Nielsen, Rasmus, 2008, In: Molecular Biology and Evolution. 25, 3, p. 568-79 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patterns of positive selection in six Mammalian genomes
Kosiol, C., Vinar, T., da Fonseca, R. R., Hubisz, M. J., Bustamante, C. D., Nielsen, Rasmus & Siepel, A., 2008, In: PLoS Genetics. 4, 8, p. e1000144Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Population genetic analysis of shotgun assemblies of genomic sequences from multiple individuals
Hellmann, I., Mang, Y., Gu, Z., Li, P., de la Vega, F. M., Clark, A. G. & Nielsen, Rasmus, 2008, In: Genome Research. 18, 7, p. 1020-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proportionally more deleterious genetic variation in European than in African populations
Lohmueller, K. E., Indap, A. R., Schmidt, S., Boyko, A. R., Hernandez, R. D., Hubisz, M. J., Sninsky, J. J., White, T. J., Sunyaev, S. R., Nielsen, Rasmus, Clark, A. G. & Bustamante, C. D., 2008, In: Nature. 451, 7181, p. 994-7 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Statistical assignment of DNA sequences using Bayesian phylogenetics
Terkelsen, K. M., Boomsma, Wouter, Huelsenbeck, J. P., Willerslev, Eske & Nielsen, Rasmus, 2008, In: Systematic Biology. 57, 5, p. 750-757 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The diploid genome sequence of an Asian individual
Wang, J., Wang, W., Li, R., Li, Y., Tian, G., Goodman, L., Fan, W., Zhang, J., Li, J., Zhang, J., Guo, Y., Feng, B., Li, H., Lu, Y., Fang, X., Liang, H., Du, Z., Li, D., Zhao, Y., Hu, Y. & 57 others, , 2008, In: Nature. 456, 7218, p. 60-65 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of ancient DNA damage on inferences of demographic histories
Axelsson, E., Willerslev, Eske, Gilbert, M Thomas P & Nielsen, Rasmus, 2008, In: Molecular Biology and Evolution. 25, 10, p. 2181-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The impact of founder events on chromosomal variability in multiply mating species
Pool, J. E. & Nielsen, Rasmus, 2008, In: Molecular Biology and Evolution. 25, 8, p. 1728-36 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
A Bayesian multilocus association method: allowing for higher-order interaction in association studies
Albrechtsen, Anders, Castella, S., Andersen, G., Hansen, T., Pedersen, O. & Nielsen, Rasmus, 2007, In: Genetics. 176, 2, p. 1197-208 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adaptive genic evolution in the Drosophila genomes
Shapiro, J. A., Huang, W., Zhang, C., Hubisz, M. J., Lu, J., Turissini, D. A., Fang, S., Wang, H., Hudson, R. R., Nielsen, Rasmus, Chen, Z. & Wu, C., 2007, In: Proceedings of the National Academy of Science of the United States of America. 104, 7, p. 2271-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancient bacteria show evidence of DNA repair.
Johnson, S. S., Hebsgaard, M. B., Christensen, T. R., Mastepanov, M., Nielsen, Rasmus, Munch, K., Brand, T., Gilbert, M Thomas P, Zuber, M. T., Bunce, M., Rønn, Regin, Gilichinsky, D., Froese, D. & Willerslev, Eske, 2007, In: Proceedings of the National Academy of Science of the United States of America. 104, 36, p. 14401-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancient biomolecules from deep ice cores reveal a forested southern Greenland.
Willerslev, E., Cappellini, E., Boomsma, W. K., Nielsen, R., Hebsgaard, M. B., Brand, T. B., Hofreiter, M., Bunce, M., Poinar, H. N., Dahl-Jensen, D., Johnsen, S. J., Steffensen, J. P., Bennike, O., Schwenninger, J-L., Nathan, R., Armitage, S., de Hoog, C-J., Alfimov, V., Christl, M., Beer, J. & 10 others, , 2007, In: Science. 317, 5834, p. 111-114 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Demographic histories and patterns of linkage disequilibrium in Chinese and Indian rhesus macaques
Hernandez, R. D., Hubisz, M. J., Wheeler, D. A., Smith, D. G., Ferguson, B., Rogers, J., Nazareth, L., Indap, A., Bourquin, T., McPherson, J., Muzny, D., Gibbs, R., Nielsen, Rasmus & Bustamante, C. D., 2007, In: Science. 316, 5822, p. 240-3 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dependence of paracentric inversion rate on tract length
York, T. L., Durrett, R. & Nielsen, Rasmus, 2007, In: BMC Bioinformatics. 8, p. 115Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evolution of genes and genomes on the Drosophila phylogeny. Drosophila 12 Genomes Consortium
Clark, A. G., Eisen, M. B., Smith, D. R., Bergman, C. M., Oliver, B., Markow, T. A., Kaufman, T. C., Kellis, M., Gelbart, W., Iyer, V. N., Pollard, D. A., Sackton, T. B., Larracuente, A. M., Singh, N. D., Abad, J. P., Abt, D. N., Adryan, B., Aguade, M., Akashi, H., Anderson, W. W. & 31 others, , 2007, In: Nature. 450, 7167, p. 203-18 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evolutionary and biomedical insights from the rhesus macaque genome
Gibbs, R. A., Rogers, J., Katze, M. G., Bumgarner, R., Weinstock, G. M., Mardis, E. R., Remington, K. A., Strausberg, R. L., Venter, J. C., Wilson, R. K., Batzer, M. A., Bustamante, C. D., Eichler, E. E., Hahn, M. W., Hardison, R. C., Makova, K. D., Miller, W., Milosavljevic, A., Palermo, R. E., Siepel, A. & 31 others, , 2007, In: Science. 316, 5822, p. 222-34 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploring variation in the d(N)/d(S) ratio among sites and lineages using mutational mappings: applications to the influenza virus
Zhai, W., Slatkin, M. & Nielsen, Rasmus, 2007, In: Journal of Molecular Evolution. 65, 3, p. 340-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Finding cis-regulatory modules in Drosophila using phylogenetic hidden Markov models
Wong, W. S. W. & Nielsen, Rasmus, 2007, In: Bioinformatics. 23, 16, p. 2031-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genes under positive selection in Escherichia coli
Petersen, L., Bollback, J. P., Dimmic, M., Hubisz, M. & Nielsen, Rasmus, 2007, In: Genome Research. 17, 9, p. 1336-43 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide patterns of nucleotide polymorphism in domesticated rice
Caicedo, A. L., Williamson, S. H., Hernandez, R. D., Boyko, A., Fledel-Alon, A., York, T. L., Polato, N. R., Olsen, K. M., Nielsen, Rasmus, McCouch, S. R., Bustamante, C. D. & Purugganan, M. D., 2007, In: PLoS Genetics. 3, 9, p. 1745-56 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 3311
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
Research output: Contribution to journal › Journal article › Research › peer-review
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SNP calling, genotype calling, and sample allele frequency estimation from new-generation sequencing data
Research output: Contribution to journal › Journal article › Research › peer-review
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