Adaptation to the High-Arctic island environment despite long-term reduced genetic variation in Svalbard reindeer

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Adaptation to the High-Arctic island environment despite long-term reduced genetic variation in Svalbard reindeer. / Dussex, Nicolas; Tørresen, Ole K.; van der Valk, Tom; Le Moullec, Mathilde; Veiberg, Vebjørn; Tooming-Klunderud, Ave; Skage, Morten; Garmann-Aarhus, Benedicte; Wood, Jonathan; Rasmussen, Jacob A.; Pedersen, Åshild Ø.; Martin, Sarah L. F.; Røed, Knut H.; Jakobsen, Kjetill S.; Dalén, Love; Hansen, Brage B.; Martin, Michael D.

In: iScience, Vol. 26, No. 10, 107811, 2023.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Dussex, N, Tørresen, OK, van der Valk, T, Le Moullec, M, Veiberg, V, Tooming-Klunderud, A, Skage, M, Garmann-Aarhus, B, Wood, J, Rasmussen, JA, Pedersen, ÅØ, Martin, SLF, Røed, KH, Jakobsen, KS, Dalén, L, Hansen, BB & Martin, MD 2023, 'Adaptation to the High-Arctic island environment despite long-term reduced genetic variation in Svalbard reindeer', iScience, vol. 26, no. 10, 107811. https://doi.org/10.1016/j.isci.2023.107811

APA

Dussex, N., Tørresen, O. K., van der Valk, T., Le Moullec, M., Veiberg, V., Tooming-Klunderud, A., Skage, M., Garmann-Aarhus, B., Wood, J., Rasmussen, J. A., Pedersen, Å. Ø., Martin, S. L. F., Røed, K. H., Jakobsen, K. S., Dalén, L., Hansen, B. B., & Martin, M. D. (2023). Adaptation to the High-Arctic island environment despite long-term reduced genetic variation in Svalbard reindeer. iScience, 26(10), [107811]. https://doi.org/10.1016/j.isci.2023.107811

Vancouver

Dussex N, Tørresen OK, van der Valk T, Le Moullec M, Veiberg V, Tooming-Klunderud A et al. Adaptation to the High-Arctic island environment despite long-term reduced genetic variation in Svalbard reindeer. iScience. 2023;26(10). 107811. https://doi.org/10.1016/j.isci.2023.107811

Author

Dussex, Nicolas ; Tørresen, Ole K. ; van der Valk, Tom ; Le Moullec, Mathilde ; Veiberg, Vebjørn ; Tooming-Klunderud, Ave ; Skage, Morten ; Garmann-Aarhus, Benedicte ; Wood, Jonathan ; Rasmussen, Jacob A. ; Pedersen, Åshild Ø. ; Martin, Sarah L. F. ; Røed, Knut H. ; Jakobsen, Kjetill S. ; Dalén, Love ; Hansen, Brage B. ; Martin, Michael D. / Adaptation to the High-Arctic island environment despite long-term reduced genetic variation in Svalbard reindeer. In: iScience. 2023 ; Vol. 26, No. 10.

Bibtex

@article{bc369e093df94dfd9dc028dec08b70fc,

title = "Adaptation to the High-Arctic island environment despite long-term reduced genetic variation in Svalbard reindeer",

abstract = "Typically much smaller in number than their mainland counterparts, island populations are ideal systems to investigate genetic threats to small populations. The Svalbard reindeer (Rangifer tarandus platyrhynchus) is an endemic subspecies that colonized the Svalbard archipelago ca. 6,000–8,000 years ago and now shows numerous physiological and morphological adaptations to its arctic habitat. Here, we report a de-novo chromosome-level assembly for Svalbard reindeer and analyze 133 reindeer genomes spanning Svalbard and most of the species{\textquoteright} Holarctic range, to examine the genomic consequences of long-term isolation and small population size in this insular subspecies. Empirical data, demographic reconstructions, and forward simulations show that long-term isolation and high inbreeding levels may have facilitated the reduction of highly deleterious—and to a lesser extent, moderately deleterious—variation. Our study indicates that long-term reduced genetic diversity did not preclude local adaptation to the High Arctic, suggesting that even severely bottlenecked populations can retain evolutionary potential.",

keywords = "Animal species, Genomics, Sequence analysis",

author = "Nicolas Dussex and T{\o}rresen, {Ole K.} and {van der Valk}, Tom and {Le Moullec}, Mathilde and Vebj{\o}rn Veiberg and Ave Tooming-Klunderud and Morten Skage and Benedicte Garmann-Aarhus and Jonathan Wood and Rasmussen, {Jacob A.} and Pedersen, {{\AA}shild {\O}.} and Martin, {Sarah L. F.} and R{\o}ed, {Knut H.} and Jakobsen, {Kjetill S.} and Love Dal{\'e}n and Hansen, {Brage B.} and Martin, {Michael D.}",

note = "Publisher Copyright: {\textcopyright} 2023 The Author(s)",

year = "2023",

doi = "10.1016/j.isci.2023.107811",

language = "English",

volume = "26",

journal = "iScience",

issn = "2589-0042",

publisher = "Elsevier",

number = "10",

}

RIS

TY - JOUR

T1 - Adaptation to the High-Arctic island environment despite long-term reduced genetic variation in Svalbard reindeer

AU - Dussex, Nicolas

AU - Tørresen, Ole K.

AU - van der Valk, Tom

AU - Le Moullec, Mathilde

AU - Veiberg, Vebjørn

AU - Tooming-Klunderud, Ave

AU - Skage, Morten

AU - Garmann-Aarhus, Benedicte

AU - Wood, Jonathan

AU - Rasmussen, Jacob A.

AU - Pedersen, Åshild Ø.

AU - Martin, Sarah L. F.

AU - Røed, Knut H.

AU - Jakobsen, Kjetill S.

AU - Dalén, Love

AU - Hansen, Brage B.

AU - Martin, Michael D.

PY - 2023

Y1 - 2023

N2 - Typically much smaller in number than their mainland counterparts, island populations are ideal systems to investigate genetic threats to small populations. The Svalbard reindeer (Rangifer tarandus platyrhynchus) is an endemic subspecies that colonized the Svalbard archipelago ca. 6,000–8,000 years ago and now shows numerous physiological and morphological adaptations to its arctic habitat. Here, we report a de-novo chromosome-level assembly for Svalbard reindeer and analyze 133 reindeer genomes spanning Svalbard and most of the species’ Holarctic range, to examine the genomic consequences of long-term isolation and small population size in this insular subspecies. Empirical data, demographic reconstructions, and forward simulations show that long-term isolation and high inbreeding levels may have facilitated the reduction of highly deleterious—and to a lesser extent, moderately deleterious—variation. Our study indicates that long-term reduced genetic diversity did not preclude local adaptation to the High Arctic, suggesting that even severely bottlenecked populations can retain evolutionary potential.

AB - Typically much smaller in number than their mainland counterparts, island populations are ideal systems to investigate genetic threats to small populations. The Svalbard reindeer (Rangifer tarandus platyrhynchus) is an endemic subspecies that colonized the Svalbard archipelago ca. 6,000–8,000 years ago and now shows numerous physiological and morphological adaptations to its arctic habitat. Here, we report a de-novo chromosome-level assembly for Svalbard reindeer and analyze 133 reindeer genomes spanning Svalbard and most of the species’ Holarctic range, to examine the genomic consequences of long-term isolation and small population size in this insular subspecies. Empirical data, demographic reconstructions, and forward simulations show that long-term isolation and high inbreeding levels may have facilitated the reduction of highly deleterious—and to a lesser extent, moderately deleterious—variation. Our study indicates that long-term reduced genetic diversity did not preclude local adaptation to the High Arctic, suggesting that even severely bottlenecked populations can retain evolutionary potential.

KW - Animal species

KW - Genomics

KW - Sequence analysis

U2 - 10.1016/j.isci.2023.107811

DO - 10.1016/j.isci.2023.107811

M3 - Journal article

C2 - 37744038

AN - SCOPUS:85171478826

VL - 26

JO - iScience

JF - iScience

SN - 2589-0042

IS - 10

M1 - 107811

ER -

ID: 369352964

Globe Institute