Ancient DNA reveals evolutionary origins of autoimmune diseases

Research output: Contribution to journal › Comment/debate › Research › peer-review

Standard

Ancient DNA reveals evolutionary origins of autoimmune diseases. / Barrie, William; Irving-Pease, Evan K.; Willerslev, Eske; Iversen, Astrid K. N.; Fugger, Lars.

In: Nature Reviews Immunology, Vol. 24, 2024, p. 85-86.

Research output: Contribution to journal › Comment/debate › Research › peer-review

Harvard

Barrie, W, Irving-Pease, EK, Willerslev, E, Iversen, AKN & Fugger, L 2024, 'Ancient DNA reveals evolutionary origins of autoimmune diseases', Nature Reviews Immunology, vol. 24, pp. 85-86. https://doi.org/10.1038/s41577-023-00983-6

APA

Barrie, W., Irving-Pease, E. K., Willerslev, E., Iversen, A. K. N., & Fugger, L. (2024). Ancient DNA reveals evolutionary origins of autoimmune diseases. Nature Reviews Immunology, 24, 85-86. https://doi.org/10.1038/s41577-023-00983-6

Vancouver

Barrie W, Irving-Pease EK, Willerslev E, Iversen AKN, Fugger L. Ancient DNA reveals evolutionary origins of autoimmune diseases. Nature Reviews Immunology. 2024;24:85-86. https://doi.org/10.1038/s41577-023-00983-6

Author

Barrie, William ; Irving-Pease, Evan K. ; Willerslev, Eske ; Iversen, Astrid K. N. ; Fugger, Lars. / Ancient DNA reveals evolutionary origins of autoimmune diseases. In: Nature Reviews Immunology. 2024 ; Vol. 24. pp. 85-86.

Bibtex

@article{58cf981ac5bf4a5b8ff6f8d0a2a096cc,
title = "Ancient DNA reveals evolutionary origins of autoimmune diseases",
abstract = "Most autoimmune diseases are caused by the interplay between common genetic risk variants and environmental factors. New studies of ancient genomes suggest that many of these variants evolved under strong selection pressures, probably due to lifestyle-specific environmental pathogens, the consequences of which shape the distribution of present-day disease risk and point to novel therapeutic interventions.",
author = "William Barrie and Irving-Pease, {Evan K.} and Eske Willerslev and Iversen, {Astrid K. N.} and Lars Fugger",
year = "2024",
doi = "10.1038/s41577-023-00983-6",
language = "English",
volume = "24",
pages = "85--86",
journal = "Nature Reviews Immunology",
issn = "1474-1733",
publisher = "Nature Publishing Group",

}

RIS

TY - JOUR

T1 - Ancient DNA reveals evolutionary origins of autoimmune diseases

AU - Barrie, William

AU - Irving-Pease, Evan K.

AU - Willerslev, Eske

AU - Iversen, Astrid K. N.

AU - Fugger, Lars

PY - 2024

Y1 - 2024

N2 - Most autoimmune diseases are caused by the interplay between common genetic risk variants and environmental factors. New studies of ancient genomes suggest that many of these variants evolved under strong selection pressures, probably due to lifestyle-specific environmental pathogens, the consequences of which shape the distribution of present-day disease risk and point to novel therapeutic interventions.

AB - Most autoimmune diseases are caused by the interplay between common genetic risk variants and environmental factors. New studies of ancient genomes suggest that many of these variants evolved under strong selection pressures, probably due to lifestyle-specific environmental pathogens, the consequences of which shape the distribution of present-day disease risk and point to novel therapeutic interventions.

U2 - 10.1038/s41577-023-00983-6

DO - 10.1038/s41577-023-00983-6

M3 - Comment/debate

C2 - 38177452

AN - SCOPUS:85181490627

VL - 24

SP - 85

EP - 86

JO - Nature Reviews Immunology

JF - Nature Reviews Immunology

SN - 1474-1733

ER -

ID: 380734896