Evolutionary and biomedical insights from the rhesus macaque genome

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Evolutionary and biomedical insights from the rhesus macaque genome. / Gibbs, Richard A; Rogers, Jeffrey; Katze, Michael G; Bumgarner, Roger; Weinstock, George M; Mardis, Elaine R; Remington, Karin A; Strausberg, Robert L; Venter, J Craig; Wilson, Richard K; Batzer, Mark A; Bustamante, Carlos D; Eichler, Evan E; Hahn, Matthew W; Hardison, Ross C; Makova, Kateryna D; Miller, Webb; Milosavljevic, Aleksandar; Palermo, Robert E; Siepel, Adam; Sikela, James M; Attaway, Tony; Bell, Stephanie; Bernard, Kelly E; Buhay, Christian J; Chandrabose, Mimi N; Dao, Marvin; Davis, Clay; Delehaunty, Kimberly D; Ding, Yan; Dinh, Huyen H; Dugan-Rocha, Shannon; Fulton, Lucinda A; Gabisi, Ramatu Ayiesha; Garner, Toni T; Godfrey, Jennifer; Hawes, Alicia C; Hernandez, Judith; Hines, Sandra; Holder, Michael; Hume, Jennifer; Jhangiani, Shalini N; Joshi, Vandita; Khan, Ziad Mohid; Kirkness, Ewen F; Cree, Andrew; Fowler, R Gerald; Lee, Sandra; Lewis, Lora R; Nielsen, Rasmus; Rhesus Macaque Genome Sequencing and Analysis Consortium.

In: Science, Vol. 316, No. 5822, 2007, p. 222-34.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Gibbs, RA, Rogers, J, Katze, MG, Bumgarner, R, Weinstock, GM, Mardis, ER, Remington, KA, Strausberg, RL, Venter, JC, Wilson, RK, Batzer, MA, Bustamante, CD, Eichler, EE, Hahn, MW, Hardison, RC, Makova, KD, Miller, W, Milosavljevic, A, Palermo, RE, Siepel, A, Sikela, JM, Attaway, T, Bell, S, Bernard, KE, Buhay, CJ, Chandrabose, MN, Dao, M, Davis, C, Delehaunty, KD, Ding, Y, Dinh, HH, Dugan-Rocha, S, Fulton, LA, Gabisi, RA, Garner, TT, Godfrey, J, Hawes, AC, Hernandez, J, Hines, S, Holder, M, Hume, J, Jhangiani, SN, Joshi, V, Khan, ZM, Kirkness, EF, Cree, A, Fowler, RG, Lee, S, Lewis, LR, Nielsen, R & Rhesus Macaque Genome Sequencing and Analysis Consortium 2007, 'Evolutionary and biomedical insights from the rhesus macaque genome', Science, vol. 316, no. 5822, pp. 222-34. https://doi.org/10.1126/science.1139247

APA

Gibbs, R. A., Rogers, J., Katze, M. G., Bumgarner, R., Weinstock, G. M., Mardis, E. R., Remington, K. A., Strausberg, R. L., Venter, J. C., Wilson, R. K., Batzer, M. A., Bustamante, C. D., Eichler, E. E., Hahn, M. W., Hardison, R. C., Makova, K. D., Miller, W., Milosavljevic, A., Palermo, R. E., ... Rhesus Macaque Genome Sequencing and Analysis Consortium (2007). Evolutionary and biomedical insights from the rhesus macaque genome. Science, 316(5822), 222-34. https://doi.org/10.1126/science.1139247

Vancouver

Gibbs RA, Rogers J, Katze MG, Bumgarner R, Weinstock GM, Mardis ER et al. Evolutionary and biomedical insights from the rhesus macaque genome. Science. 2007;316(5822):222-34. https://doi.org/10.1126/science.1139247

Author

Gibbs, Richard A ; Rogers, Jeffrey ; Katze, Michael G ; Bumgarner, Roger ; Weinstock, George M ; Mardis, Elaine R ; Remington, Karin A ; Strausberg, Robert L ; Venter, J Craig ; Wilson, Richard K ; Batzer, Mark A ; Bustamante, Carlos D ; Eichler, Evan E ; Hahn, Matthew W ; Hardison, Ross C ; Makova, Kateryna D ; Miller, Webb ; Milosavljevic, Aleksandar ; Palermo, Robert E ; Siepel, Adam ; Sikela, James M ; Attaway, Tony ; Bell, Stephanie ; Bernard, Kelly E ; Buhay, Christian J ; Chandrabose, Mimi N ; Dao, Marvin ; Davis, Clay ; Delehaunty, Kimberly D ; Ding, Yan ; Dinh, Huyen H ; Dugan-Rocha, Shannon ; Fulton, Lucinda A ; Gabisi, Ramatu Ayiesha ; Garner, Toni T ; Godfrey, Jennifer ; Hawes, Alicia C ; Hernandez, Judith ; Hines, Sandra ; Holder, Michael ; Hume, Jennifer ; Jhangiani, Shalini N ; Joshi, Vandita ; Khan, Ziad Mohid ; Kirkness, Ewen F ; Cree, Andrew ; Fowler, R Gerald ; Lee, Sandra ; Lewis, Lora R ; Nielsen, Rasmus ; Rhesus Macaque Genome Sequencing and Analysis Consortium. / Evolutionary and biomedical insights from the rhesus macaque genome. In: Science. 2007 ; Vol. 316, No. 5822. pp. 222-34.

Bibtex

@article{fda84ef0194411deb43e000ea68e967b,
title = "Evolutionary and biomedical insights from the rhesus macaque genome",
abstract = "The rhesus macaque (Macaca mulatta) is an abundant primate species that diverged from the ancestors of Homo sapiens about 25 million years ago. Because they are genetically and physiologically similar to humans, rhesus monkeys are the most widely used nonhuman primate in basic and applied biomedical research. We determined the genome sequence of an Indian-origin Macaca mulatta female and compared the data with chimpanzees and humans to reveal the structure of ancestral primate genomes and to identify evidence for positive selection and lineage-specific expansions and contractions of gene families. A comparison of sequences from individual animals was used to investigate their underlying genetic diversity. The complete description of the macaque genome blueprint enhances the utility of this animal model for biomedical research and improves our understanding of the basic biology of the species.",
author = "Gibbs, {Richard A} and Jeffrey Rogers and Katze, {Michael G} and Roger Bumgarner and Weinstock, {George M} and Mardis, {Elaine R} and Remington, {Karin A} and Strausberg, {Robert L} and Venter, {J Craig} and Wilson, {Richard K} and Batzer, {Mark A} and Bustamante, {Carlos D} and Eichler, {Evan E} and Hahn, {Matthew W} and Hardison, {Ross C} and Makova, {Kateryna D} and Webb Miller and Aleksandar Milosavljevic and Palermo, {Robert E} and Adam Siepel and Sikela, {James M} and Tony Attaway and Stephanie Bell and Bernard, {Kelly E} and Buhay, {Christian J} and Chandrabose, {Mimi N} and Marvin Dao and Clay Davis and Delehaunty, {Kimberly D} and Yan Ding and Dinh, {Huyen H} and Shannon Dugan-Rocha and Fulton, {Lucinda A} and Gabisi, {Ramatu Ayiesha} and Garner, {Toni T} and Jennifer Godfrey and Hawes, {Alicia C} and Judith Hernandez and Sandra Hines and Michael Holder and Jennifer Hume and Jhangiani, {Shalini N} and Vandita Joshi and Khan, {Ziad Mohid} and Kirkness, {Ewen F} and Andrew Cree and Fowler, {R Gerald} and Sandra Lee and Lewis, {Lora R} and Rasmus Nielsen and {Rhesus Macaque Genome Sequencing and Analysis Consortium}",
note = "Keywords: Animals; Biomedical Research; Evolution, Molecular; Female; Gene Duplication; Gene Rearrangement; Genetic Diseases, Inborn; Genetic Variation; Genome; Humans; Macaca mulatta; Male; Multigene Family; Mutation; Pan troglodytes; Sequence Analysis, DNA; Species Specificity",
year = "2007",
doi = "10.1126/science.1139247",
language = "English",
volume = "316",
pages = "222--34",
journal = "Science",
issn = "0036-8075",
publisher = "American Association for the Advancement of Science",
number = "5822",

}

RIS

TY - JOUR

T1 - Evolutionary and biomedical insights from the rhesus macaque genome

AU - Gibbs, Richard A

AU - Rogers, Jeffrey

AU - Katze, Michael G

AU - Bumgarner, Roger

AU - Weinstock, George M

AU - Mardis, Elaine R

AU - Remington, Karin A

AU - Strausberg, Robert L

AU - Venter, J Craig

AU - Wilson, Richard K

AU - Batzer, Mark A

AU - Bustamante, Carlos D

AU - Eichler, Evan E

AU - Hahn, Matthew W

AU - Hardison, Ross C

AU - Makova, Kateryna D

AU - Miller, Webb

AU - Milosavljevic, Aleksandar

AU - Palermo, Robert E

AU - Siepel, Adam

AU - Sikela, James M

AU - Attaway, Tony

AU - Bell, Stephanie

AU - Bernard, Kelly E

AU - Buhay, Christian J

AU - Chandrabose, Mimi N

AU - Dao, Marvin

AU - Davis, Clay

AU - Delehaunty, Kimberly D

AU - Ding, Yan

AU - Dinh, Huyen H

AU - Dugan-Rocha, Shannon

AU - Fulton, Lucinda A

AU - Gabisi, Ramatu Ayiesha

AU - Garner, Toni T

AU - Godfrey, Jennifer

AU - Hawes, Alicia C

AU - Hernandez, Judith

AU - Hines, Sandra

AU - Holder, Michael

AU - Hume, Jennifer

AU - Jhangiani, Shalini N

AU - Joshi, Vandita

AU - Khan, Ziad Mohid

AU - Kirkness, Ewen F

AU - Cree, Andrew

AU - Fowler, R Gerald

AU - Lee, Sandra

AU - Lewis, Lora R

AU - Nielsen, Rasmus

AU - Rhesus Macaque Genome Sequencing and Analysis Consortium

N1 - Keywords: Animals; Biomedical Research; Evolution, Molecular; Female; Gene Duplication; Gene Rearrangement; Genetic Diseases, Inborn; Genetic Variation; Genome; Humans; Macaca mulatta; Male; Multigene Family; Mutation; Pan troglodytes; Sequence Analysis, DNA; Species Specificity

PY - 2007

Y1 - 2007

N2 - The rhesus macaque (Macaca mulatta) is an abundant primate species that diverged from the ancestors of Homo sapiens about 25 million years ago. Because they are genetically and physiologically similar to humans, rhesus monkeys are the most widely used nonhuman primate in basic and applied biomedical research. We determined the genome sequence of an Indian-origin Macaca mulatta female and compared the data with chimpanzees and humans to reveal the structure of ancestral primate genomes and to identify evidence for positive selection and lineage-specific expansions and contractions of gene families. A comparison of sequences from individual animals was used to investigate their underlying genetic diversity. The complete description of the macaque genome blueprint enhances the utility of this animal model for biomedical research and improves our understanding of the basic biology of the species.

AB - The rhesus macaque (Macaca mulatta) is an abundant primate species that diverged from the ancestors of Homo sapiens about 25 million years ago. Because they are genetically and physiologically similar to humans, rhesus monkeys are the most widely used nonhuman primate in basic and applied biomedical research. We determined the genome sequence of an Indian-origin Macaca mulatta female and compared the data with chimpanzees and humans to reveal the structure of ancestral primate genomes and to identify evidence for positive selection and lineage-specific expansions and contractions of gene families. A comparison of sequences from individual animals was used to investigate their underlying genetic diversity. The complete description of the macaque genome blueprint enhances the utility of this animal model for biomedical research and improves our understanding of the basic biology of the species.

U2 - 10.1126/science.1139247

DO - 10.1126/science.1139247

M3 - Journal article

C2 - 17431167

VL - 316

SP - 222

EP - 234

JO - Science

JF - Science

SN - 0036-8075

IS - 5822

ER -

ID: 11528955