Mapping Mutations on Phylogenies

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

Standard

Mapping Mutations on Phylogenies. / Nielsen, Rasmus.

Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. ed. / Michael J. Dunn; Lynn B. Jorde; Peter F. R. Little; Shankar Subramaniam. Wiley, 2005.

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

Harvard

Nielsen, R 2005, Mapping Mutations on Phylogenies. in MJ Dunn, LB Jorde, PFR Little & S Subramaniam (eds), Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. Wiley. https://doi.org/10.1002/047001153X.g404309

APA

Nielsen, R. (2005). Mapping Mutations on Phylogenies. In M. J. Dunn, L. B. Jorde, P. F. R. Little, & S. Subramaniam (Eds.), Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics Wiley. https://doi.org/10.1002/047001153X.g404309

Vancouver

Nielsen R. Mapping Mutations on Phylogenies. In Dunn MJ, Jorde LB, Little PFR, Subramaniam S, editors, Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. Wiley. 2005 https://doi.org/10.1002/047001153X.g404309

Author

Nielsen, Rasmus. / Mapping Mutations on Phylogenies. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. editor / Michael J. Dunn ; Lynn B. Jorde ; Peter F. R. Little ; Shankar Subramaniam. Wiley, 2005.

Bibtex

@inbook{82f0f06074c111dbbee902004c4f4f50,
title = "Mapping Mutations on Phylogenies",
abstract = "This chapter provides a short review of recent methodologies developed for mapping mutations on phylogenies. Mapping of mutations, or character changes in general, using the maximum parsimony principle has been one of the most powerful tools in phylogenetics, and it has been used in a variety of different applications, for example, in the detection of correlated evolution and to identify selection acting on DNA sequences. However, many uses of parsimony mappings have been criticized because they focus on only one of many possible mappings and/or because they do not incorporate statistical uncertainty in the mapping. Recently developed probabilistic methods can incorporate statistical uncertainty in the character mappings. In these methods, focus is on a probability distribution of mutational mappings instead of a single estimate of the mutational mapping.",
author = "Rasmus Nielsen",
note = "Keywords: phylogeny; Bayesian analysis; mapping mutations; parsimony",
year = "2005",
doi = "10.1002/047001153X.g404309",
language = "English",
isbn = "978-0-470-84974-3",
editor = "Dunn, {Michael J.} and Jorde, {Lynn B.} and Little, {Peter F. R.} and Shankar Subramaniam",
booktitle = "Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics",
publisher = "Wiley",
address = "United States",

}

RIS

TY - CHAP

T1 - Mapping Mutations on Phylogenies

AU - Nielsen, Rasmus

N1 - Keywords: phylogeny; Bayesian analysis; mapping mutations; parsimony

PY - 2005

Y1 - 2005

N2 - This chapter provides a short review of recent methodologies developed for mapping mutations on phylogenies. Mapping of mutations, or character changes in general, using the maximum parsimony principle has been one of the most powerful tools in phylogenetics, and it has been used in a variety of different applications, for example, in the detection of correlated evolution and to identify selection acting on DNA sequences. However, many uses of parsimony mappings have been criticized because they focus on only one of many possible mappings and/or because they do not incorporate statistical uncertainty in the mapping. Recently developed probabilistic methods can incorporate statistical uncertainty in the character mappings. In these methods, focus is on a probability distribution of mutational mappings instead of a single estimate of the mutational mapping.

AB - This chapter provides a short review of recent methodologies developed for mapping mutations on phylogenies. Mapping of mutations, or character changes in general, using the maximum parsimony principle has been one of the most powerful tools in phylogenetics, and it has been used in a variety of different applications, for example, in the detection of correlated evolution and to identify selection acting on DNA sequences. However, many uses of parsimony mappings have been criticized because they focus on only one of many possible mappings and/or because they do not incorporate statistical uncertainty in the mapping. Recently developed probabilistic methods can incorporate statistical uncertainty in the character mappings. In these methods, focus is on a probability distribution of mutational mappings instead of a single estimate of the mutational mapping.

U2 - 10.1002/047001153X.g404309

DO - 10.1002/047001153X.g404309

M3 - Book chapter

SN - 978-0-470-84974-3

BT - Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics

A2 - Dunn, Michael J.

A2 - Jorde, Lynn B.

A2 - Little, Peter F. R.

A2 - Subramaniam, Shankar

PB - Wiley

ER -

ID: 60803