Massive haplotypes underlie ecotypic differentiation in sunflowers

Research output: Contribution to journal › Journal article › Research › peer-review

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Massive haplotypes underlie ecotypic differentiation in sunflowers. / Todesco, Marco; Owens, Gregory L.; Bercovich, Natalia; Légaré, Jean Sébastien; Soudi, Shaghayegh; Burge, Dylan O.; Huang, Kaichi; Ostevik, Katherine L.; Drummond, Emily B. M.; Imerovski, Ivana; Lande, Kathryn; Pascual-Robles, Mariana A.; Nanavati, Mihir; Jahani, Mojtaba; Cheung, Winnie; Staton, S. Evan; Muños, Stéphane; Nielsen, Rasmus; Donovan, Lisa A.; Burke, John M.; Yeaman, Sam; Rieseberg, Loren H.

In: Nature, Vol. 584, No. 7822, 2020, p. 602-607.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Todesco, M, Owens, GL, Bercovich, N, Légaré, JS, Soudi, S, Burge, DO, Huang, K, Ostevik, KL, Drummond, EBM, Imerovski, I, Lande, K, Pascual-Robles, MA, Nanavati, M, Jahani, M, Cheung, W, Staton, SE, Muños, S, Nielsen, R, Donovan, LA, Burke, JM, Yeaman, S & Rieseberg, LH 2020, 'Massive haplotypes underlie ecotypic differentiation in sunflowers', Nature, vol. 584, no. 7822, pp. 602-607. https://doi.org/10.1038/s41586-020-2467-6

APA

Todesco, M., Owens, G. L., Bercovich, N., Légaré, J. S., Soudi, S., Burge, D. O., Huang, K., Ostevik, K. L., Drummond, E. B. M., Imerovski, I., Lande, K., Pascual-Robles, M. A., Nanavati, M., Jahani, M., Cheung, W., Staton, S. E., Muños, S., Nielsen, R., Donovan, L. A., ... Rieseberg, L. H. (2020). Massive haplotypes underlie ecotypic differentiation in sunflowers. Nature, 584(7822), 602-607. https://doi.org/10.1038/s41586-020-2467-6

Vancouver

Todesco M, Owens GL, Bercovich N, Légaré JS, Soudi S, Burge DO et al. Massive haplotypes underlie ecotypic differentiation in sunflowers. Nature. 2020;584(7822):602-607. https://doi.org/10.1038/s41586-020-2467-6

Author

Todesco, Marco ; Owens, Gregory L. ; Bercovich, Natalia ; Légaré, Jean Sébastien ; Soudi, Shaghayegh ; Burge, Dylan O. ; Huang, Kaichi ; Ostevik, Katherine L. ; Drummond, Emily B. M. ; Imerovski, Ivana ; Lande, Kathryn ; Pascual-Robles, Mariana A. ; Nanavati, Mihir ; Jahani, Mojtaba ; Cheung, Winnie ; Staton, S. Evan ; Muños, Stéphane ; Nielsen, Rasmus ; Donovan, Lisa A. ; Burke, John M. ; Yeaman, Sam ; Rieseberg, Loren H. / Massive haplotypes underlie ecotypic differentiation in sunflowers. In: Nature. 2020 ; Vol. 584, No. 7822. pp. 602-607.

Bibtex

@article{3cf876a948b04a8da17c3d25477edf5e,

title = "Massive haplotypes underlie ecotypic differentiation in sunflowers",

abstract = "Species often include multiple ecotypes that are adapted to different environments1. However, it is unclear how ecotypes arise and how their distinctive combinations of adaptive alleles are maintained despite hybridization with non-adapted populations2–4. Here, by resequencing 1,506 wild sunflowers from 3 species (Helianthus annuus, Helianthus petiolaris and Helianthus argophyllus), we identify 37 large (1–100 Mbp in size), non-recombining haplotype blocks that are associated with numerous ecologically relevant traits, as well as soil and climate characteristics. Limited recombination in these haplotype blocks keeps adaptive alleles together, and these regions differentiate sunflower ecotypes. For example, haplotype blocks control a 77-day difference in flowering between ecotypes of the silverleaf sunflower H. argophyllus (probably through deletion of a homologue of FLOWERING LOCUS T (FT)), and are associated with seed size, flowering time and soil fertility in dune-adapted sunflowers. These haplotypes are highly divergent, frequently associated with structural variants and often appear to represent introgressions from other—possibly now-extinct—congeners. These results highlight a pervasive role of structural variation in ecotypic adaptation.",

author = "Marco Todesco and Owens, {Gregory L.} and Natalia Bercovich and L{\'e}gar{\'e}, {Jean S{\'e}bastien} and Shaghayegh Soudi and Burge, {Dylan O.} and Kaichi Huang and Ostevik, {Katherine L.} and Drummond, {Emily B. M.} and Ivana Imerovski and Kathryn Lande and Pascual-Robles, {Mariana A.} and Mihir Nanavati and Mojtaba Jahani and Winnie Cheung and Staton, {S. Evan} and St{\'e}phane Mu{\~n}os and Rasmus Nielsen and Donovan, {Lisa A.} and Burke, {John M.} and Sam Yeaman and Rieseberg, {Loren H.}",

note = "Publisher Copyright: {\textcopyright} 2020, The Author(s), under exclusive licence to Springer Nature Limited.",

year = "2020",

doi = "10.1038/s41586-020-2467-6",

language = "English",

volume = "584",

pages = "602--607",

journal = "Nature",

issn = "0028-0836",

publisher = "nature publishing group",

number = "7822",

}

RIS

TY - JOUR

T1 - Massive haplotypes underlie ecotypic differentiation in sunflowers

AU - Todesco, Marco

AU - Owens, Gregory L.

AU - Bercovich, Natalia

AU - Légaré, Jean Sébastien

AU - Soudi, Shaghayegh

AU - Burge, Dylan O.

AU - Huang, Kaichi

AU - Ostevik, Katherine L.

AU - Drummond, Emily B. M.

AU - Imerovski, Ivana

AU - Lande, Kathryn

AU - Pascual-Robles, Mariana A.

AU - Nanavati, Mihir

AU - Jahani, Mojtaba

AU - Cheung, Winnie

AU - Staton, S. Evan

AU - Muños, Stéphane

AU - Nielsen, Rasmus

AU - Donovan, Lisa A.

AU - Burke, John M.

AU - Yeaman, Sam

AU - Rieseberg, Loren H.

PY - 2020

Y1 - 2020

N2 - Species often include multiple ecotypes that are adapted to different environments1. However, it is unclear how ecotypes arise and how their distinctive combinations of adaptive alleles are maintained despite hybridization with non-adapted populations2–4. Here, by resequencing 1,506 wild sunflowers from 3 species (Helianthus annuus, Helianthus petiolaris and Helianthus argophyllus), we identify 37 large (1–100 Mbp in size), non-recombining haplotype blocks that are associated with numerous ecologically relevant traits, as well as soil and climate characteristics. Limited recombination in these haplotype blocks keeps adaptive alleles together, and these regions differentiate sunflower ecotypes. For example, haplotype blocks control a 77-day difference in flowering between ecotypes of the silverleaf sunflower H. argophyllus (probably through deletion of a homologue of FLOWERING LOCUS T (FT)), and are associated with seed size, flowering time and soil fertility in dune-adapted sunflowers. These haplotypes are highly divergent, frequently associated with structural variants and often appear to represent introgressions from other—possibly now-extinct—congeners. These results highlight a pervasive role of structural variation in ecotypic adaptation.

AB - Species often include multiple ecotypes that are adapted to different environments1. However, it is unclear how ecotypes arise and how their distinctive combinations of adaptive alleles are maintained despite hybridization with non-adapted populations2–4. Here, by resequencing 1,506 wild sunflowers from 3 species (Helianthus annuus, Helianthus petiolaris and Helianthus argophyllus), we identify 37 large (1–100 Mbp in size), non-recombining haplotype blocks that are associated with numerous ecologically relevant traits, as well as soil and climate characteristics. Limited recombination in these haplotype blocks keeps adaptive alleles together, and these regions differentiate sunflower ecotypes. For example, haplotype blocks control a 77-day difference in flowering between ecotypes of the silverleaf sunflower H. argophyllus (probably through deletion of a homologue of FLOWERING LOCUS T (FT)), and are associated with seed size, flowering time and soil fertility in dune-adapted sunflowers. These haplotypes are highly divergent, frequently associated with structural variants and often appear to represent introgressions from other—possibly now-extinct—congeners. These results highlight a pervasive role of structural variation in ecotypic adaptation.

U2 - 10.1038/s41586-020-2467-6

DO - 10.1038/s41586-020-2467-6

M3 - Journal article

C2 - 32641831

AN - SCOPUS:85087687619

VL - 584

SP - 602

EP - 607

JO - Nature

JF - Nature

SN - 0028-0836

IS - 7822

ER -

ID: 336610678

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