Phenotypic Characterization and Comparative Genomic Analysis of Novel Salmonella Bacteriophages Isolated from a Tropical Rainforest

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Phenotypic Characterization and Comparative Genomic Analysis of Novel Salmonella Bacteriophages Isolated from a Tropical Rainforest. / Mutusamy, Prasanna; Singh, Kirnpal Kaur Banga; Yin, Lee Su; Petersen, Bent; Sicheritz-Ponten, Thomas; Clokie, Martha R. J.; Loke, Stella; Millard, Andrew; Parimannan, Sivachandran; Rajandas, Heera.

In: International Journal of Molecular Sciences, Vol. 24, No. 4, 3678, 2023.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Mutusamy, P, Singh, KKB, Yin, LS, Petersen, B, Sicheritz-Ponten, T, Clokie, MRJ, Loke, S, Millard, A, Parimannan, S & Rajandas, H 2023, 'Phenotypic Characterization and Comparative Genomic Analysis of Novel Salmonella Bacteriophages Isolated from a Tropical Rainforest', International Journal of Molecular Sciences, vol. 24, no. 4, 3678. https://doi.org/10.3390/ijms24043678

APA

Mutusamy, P., Singh, K. K. B., Yin, L. S., Petersen, B., Sicheritz-Ponten, T., Clokie, M. R. J., Loke, S., Millard, A., Parimannan, S., & Rajandas, H. (2023). Phenotypic Characterization and Comparative Genomic Analysis of Novel Salmonella Bacteriophages Isolated from a Tropical Rainforest. International Journal of Molecular Sciences, 24(4), [3678]. https://doi.org/10.3390/ijms24043678

Vancouver

Mutusamy P, Singh KKB, Yin LS, Petersen B, Sicheritz-Ponten T, Clokie MRJ et al. Phenotypic Characterization and Comparative Genomic Analysis of Novel Salmonella Bacteriophages Isolated from a Tropical Rainforest. International Journal of Molecular Sciences. 2023;24(4). 3678. https://doi.org/10.3390/ijms24043678

Author

Mutusamy, Prasanna ; Singh, Kirnpal Kaur Banga ; Yin, Lee Su ; Petersen, Bent ; Sicheritz-Ponten, Thomas ; Clokie, Martha R. J. ; Loke, Stella ; Millard, Andrew ; Parimannan, Sivachandran ; Rajandas, Heera. / Phenotypic Characterization and Comparative Genomic Analysis of Novel Salmonella Bacteriophages Isolated from a Tropical Rainforest. In: International Journal of Molecular Sciences. 2023 ; Vol. 24, No. 4.

Bibtex

@article{7fa4e082d38a4cda96a92d4d592d1538,
title = "Phenotypic Characterization and Comparative Genomic Analysis of Novel Salmonella Bacteriophages Isolated from a Tropical Rainforest",
abstract = "Salmonella infections across the globe are becoming more challenging to control due to the emergence of multidrug-resistant (MDR) strains. Lytic phages may be suitable alternatives for treating these multidrug-resistant Salmonella infections. Most Salmonella phages to date were collected from human-impacted environments. To further explore the Salmonella phage space, and to potentially identify phages with novel characteristics, we characterized Salmonella-specific phages isolated from the Penang National Park, a conserved rainforest. Four phages with a broad lytic spectrum (kills >5 Salmonella serovars) were further characterized; they have isometric heads and cone-shaped tails, and genomes of similar to 39,900 bp, encoding 49 CDSs. As the genomes share a",
keywords = "Salmonella, bacteriophages, tropical rainforest, comparative genomics, HOST-RANGE, RESISTANCE, ALIGNMENT",
author = "Prasanna Mutusamy and Singh, {Kirnpal Kaur Banga} and Yin, {Lee Su} and Bent Petersen and Thomas Sicheritz-Ponten and Clokie, {Martha R. J.} and Stella Loke and Andrew Millard and Sivachandran Parimannan and Heera Rajandas",
year = "2023",
doi = "10.3390/ijms24043678",
language = "English",
volume = "24",
journal = "International Journal of Molecular Sciences (Online)",
issn = "1661-6596",
publisher = "MDPI AG",
number = "4",

}

RIS

TY - JOUR

T1 - Phenotypic Characterization and Comparative Genomic Analysis of Novel Salmonella Bacteriophages Isolated from a Tropical Rainforest

AU - Mutusamy, Prasanna

AU - Singh, Kirnpal Kaur Banga

AU - Yin, Lee Su

AU - Petersen, Bent

AU - Sicheritz-Ponten, Thomas

AU - Clokie, Martha R. J.

AU - Loke, Stella

AU - Millard, Andrew

AU - Parimannan, Sivachandran

AU - Rajandas, Heera

PY - 2023

Y1 - 2023

N2 - Salmonella infections across the globe are becoming more challenging to control due to the emergence of multidrug-resistant (MDR) strains. Lytic phages may be suitable alternatives for treating these multidrug-resistant Salmonella infections. Most Salmonella phages to date were collected from human-impacted environments. To further explore the Salmonella phage space, and to potentially identify phages with novel characteristics, we characterized Salmonella-specific phages isolated from the Penang National Park, a conserved rainforest. Four phages with a broad lytic spectrum (kills >5 Salmonella serovars) were further characterized; they have isometric heads and cone-shaped tails, and genomes of similar to 39,900 bp, encoding 49 CDSs. As the genomes share a

AB - Salmonella infections across the globe are becoming more challenging to control due to the emergence of multidrug-resistant (MDR) strains. Lytic phages may be suitable alternatives for treating these multidrug-resistant Salmonella infections. Most Salmonella phages to date were collected from human-impacted environments. To further explore the Salmonella phage space, and to potentially identify phages with novel characteristics, we characterized Salmonella-specific phages isolated from the Penang National Park, a conserved rainforest. Four phages with a broad lytic spectrum (kills >5 Salmonella serovars) were further characterized; they have isometric heads and cone-shaped tails, and genomes of similar to 39,900 bp, encoding 49 CDSs. As the genomes share a

KW - Salmonella

KW - bacteriophages

KW - tropical rainforest

KW - comparative genomics

KW - HOST-RANGE

KW - RESISTANCE

KW - ALIGNMENT

U2 - 10.3390/ijms24043678

DO - 10.3390/ijms24043678

M3 - Journal article

C2 - 36835084

VL - 24

JO - International Journal of Molecular Sciences (Online)

JF - International Journal of Molecular Sciences (Online)

SN - 1661-6596

IS - 4

M1 - 3678

ER -

ID: 339326118