Positive selection on the killer whale mitogenome

Research output: Contribution to journal › Letter › Research › peer-review

Standard

Positive selection on the killer whale mitogenome. / Foote, Andrew David; Morin, Phillip A.; Durban, John W.; Pitman, Robert L.; Wade, Paul; Willerslev, Eske; Gilbert, Tom; Rodrigues da Fonseca, Rute Andreia.

In: Biology Letters, Vol. 7, No. 1, 2011, p. 116-118.

Research output: Contribution to journal › Letter › Research › peer-review

Harvard

Foote, AD, Morin, PA, Durban, JW, Pitman, RL, Wade, P, Willerslev, E, Gilbert, T & Rodrigues da Fonseca, RA 2011, 'Positive selection on the killer whale mitogenome', Biology Letters, vol. 7, no. 1, pp. 116-118. https://doi.org/10.1098/rsbl.2010.0638

APA

Foote, A. D., Morin, P. A., Durban, J. W., Pitman, R. L., Wade, P., Willerslev, E., Gilbert, T., & Rodrigues da Fonseca, R. A. (2011). Positive selection on the killer whale mitogenome. Biology Letters, 7(1), 116-118. https://doi.org/10.1098/rsbl.2010.0638

Vancouver

Foote AD, Morin PA, Durban JW, Pitman RL, Wade P, Willerslev E et al. Positive selection on the killer whale mitogenome. Biology Letters. 2011;7(1):116-118. https://doi.org/10.1098/rsbl.2010.0638

Author

Foote, Andrew David ; Morin, Phillip A. ; Durban, John W. ; Pitman, Robert L. ; Wade, Paul ; Willerslev, Eske ; Gilbert, Tom ; Rodrigues da Fonseca, Rute Andreia. / Positive selection on the killer whale mitogenome. In: Biology Letters. 2011 ; Vol. 7, No. 1. pp. 116-118.

Bibtex

@article{95e435cc7f1541819b1cf9aaf8fba5d6,
title = "Positive selection on the killer whale mitogenome",
abstract = "Mitochondria produce up to 95 per cent of the eukaryotic cell's energy. The coding genes of the mitochondrial DNA may therefore evolve under selection owing to metabolic requirements. The killer whale, Orcinus orca, is polymorphic, has a global distribution and occupies a range of ecological niches. It is therefore a suitable organism for testing this hypothesis. We compared a global dataset of the complete mitochondrial genomes of 139 individuals for amino acid changes that were associated with radical physico-chemical property changes and were influenced by positive selection. Two such selected non-synonymous amino acid changes were found; one in each of two ecotypes that inhabit the Antarctic pack ice. Both substitutions were associated with changes in local polarity, increased steric constraints and alpha-helical tendencies that could influence overall metabolic performance, suggesting a functional change.",
author = "Foote, {Andrew David} and Morin, {Phillip A.} and Durban, {John W.} and Pitman, {Robert L.} and Paul Wade and Eske Willerslev and Tom Gilbert and {Rodrigues da Fonseca}, {Rute Andreia}",
year = "2011",
doi = "10.1098/rsbl.2010.0638",
language = "English",
volume = "7",
pages = "116--118",
journal = "Biology Letters",
issn = "1744-9561",
publisher = "The/Royal Society",
number = "1",

}

RIS

TY - JOUR

T1 - Positive selection on the killer whale mitogenome

AU - Foote, Andrew David

AU - Morin, Phillip A.

AU - Durban, John W.

AU - Pitman, Robert L.

AU - Wade, Paul

AU - Willerslev, Eske

AU - Gilbert, Tom

AU - Rodrigues da Fonseca, Rute Andreia

PY - 2011

Y1 - 2011

N2 - Mitochondria produce up to 95 per cent of the eukaryotic cell's energy. The coding genes of the mitochondrial DNA may therefore evolve under selection owing to metabolic requirements. The killer whale, Orcinus orca, is polymorphic, has a global distribution and occupies a range of ecological niches. It is therefore a suitable organism for testing this hypothesis. We compared a global dataset of the complete mitochondrial genomes of 139 individuals for amino acid changes that were associated with radical physico-chemical property changes and were influenced by positive selection. Two such selected non-synonymous amino acid changes were found; one in each of two ecotypes that inhabit the Antarctic pack ice. Both substitutions were associated with changes in local polarity, increased steric constraints and alpha-helical tendencies that could influence overall metabolic performance, suggesting a functional change.

AB - Mitochondria produce up to 95 per cent of the eukaryotic cell's energy. The coding genes of the mitochondrial DNA may therefore evolve under selection owing to metabolic requirements. The killer whale, Orcinus orca, is polymorphic, has a global distribution and occupies a range of ecological niches. It is therefore a suitable organism for testing this hypothesis. We compared a global dataset of the complete mitochondrial genomes of 139 individuals for amino acid changes that were associated with radical physico-chemical property changes and were influenced by positive selection. Two such selected non-synonymous amino acid changes were found; one in each of two ecotypes that inhabit the Antarctic pack ice. Both substitutions were associated with changes in local polarity, increased steric constraints and alpha-helical tendencies that could influence overall metabolic performance, suggesting a functional change.

U2 - 10.1098/rsbl.2010.0638

DO - 10.1098/rsbl.2010.0638

M3 - Letter

C2 - 20810427

VL - 7

SP - 116

EP - 118

JO - Biology Letters

JF - Biology Letters

SN - 1744-9561

IS - 1

ER -

ID: 32221087