Stone Age “chewing gum” yields 5,700 yearold human genome and oral microbiome

Research output: Working paper › Preprint › Research

Standard

Stone Age “chewing gum” yields 5,700 yearold human genome and oral microbiome. / Jensen, T. Z. T.; Niemann, J.; Iversen, K. Højholt; Fotaki, A. K.; Gopalakrishan, S.; Sinding, M.-H. S.; Ellegaard, M. R.; Allentoft, M. E.; Lanigan, L. T.; Taurozzi, A. J.; Nielsen, S. Holtsmark; Dee, M. W.; Mortensen, M. N.; Christensen, M. C.; Sørensen, S. A.; Collins, M. J.; Gilbert, M. T. P.; Sikora, M.; Rasmussen, S.; Schroeder, H.

bioRxiv, 2018.

Research output: Working paper › Preprint › Research

Harvard

Jensen, TZT, Niemann, J, Iversen, KH, Fotaki, AK, Gopalakrishan, S, Sinding, M-HS, Ellegaard, MR, Allentoft, ME, Lanigan, LT, Taurozzi, AJ, Nielsen, SH, Dee, MW, Mortensen, MN, Christensen, MC, Sørensen, SA, Collins, MJ, Gilbert, MTP, Sikora, M, Rasmussen, S & Schroeder, H 2018 'Stone Age “chewing gum” yields 5,700 yearold human genome and oral microbiome' bioRxiv.

APA

Jensen, T. Z. T., Niemann, J., Iversen, K. H., Fotaki, A. K., Gopalakrishan, S., Sinding, M-H. S., Ellegaard, M. R., Allentoft, M. E., Lanigan, L. T., Taurozzi, A. J., Nielsen, S. H., Dee, M. W., Mortensen, M. N., Christensen, M. C., Sørensen, S. A., Collins, M. J., Gilbert, M. T. P., Sikora, M., Rasmussen, S., & Schroeder, H. (2018). Stone Age “chewing gum” yields 5,700 yearold human genome and oral microbiome. bioRxiv.

Vancouver

Jensen TZT, Niemann J, Iversen KH, Fotaki AK, Gopalakrishan S, Sinding M-HS et al. Stone Age “chewing gum” yields 5,700 yearold human genome and oral microbiome. bioRxiv. 2018.

Author

Jensen, T. Z. T. ; Niemann, J. ; Iversen, K. Højholt ; Fotaki, A. K. ; Gopalakrishan, S. ; Sinding, M.-H. S. ; Ellegaard, M. R. ; Allentoft, M. E. ; Lanigan, L. T. ; Taurozzi, A. J. ; Nielsen, S. Holtsmark ; Dee, M. W. ; Mortensen, M. N. ; Christensen, M. C. ; Sørensen, S. A. ; Collins, M. J. ; Gilbert, M. T. P. ; Sikora, M. ; Rasmussen, S. ; Schroeder, H. / Stone Age “chewing gum” yields 5,700 yearold human genome and oral microbiome. bioRxiv, 2018.

Bibtex

@techreport{5de9f09e76ca41378e44dd6f74153c1f,
title = "Stone Age “chewing gum” yields 5,700 yearold human genome and oral microbiome",
abstract = "We present a complete ancient human genome and oral microbiome sequenced from apiece of resinous “chewing gum” recovered from a Stone Age site on the island of Lolland,Denmark, and directly dated to 5,8585,661 cal. BP (GrM13305; 5,007±1 1). We sequenced thegenome to an average depthofcoverage of 2.3× and find that the individual who chewed theresin was female and genetically more closely related to western huntergatherers from mainlandEurope, than huntergatherers from central Scandinavia. We use imputed genotypes to predictphysical characteristics and find that she had dark skin and hair, and blue eyes. Lastly, we alsorecovered microbial DNA that is characteristic of an oral microbiome and faunal reads that likelyassociate with diet. The results highlight the potential for this type of sample material as a newsource of ancient human and microbial DNA.",
author = "Jensen, {T. Z. T.} and J. Niemann and Iversen, {K. H{\o}jholt} and Fotaki, {A. K.} and S. Gopalakrishan and Sinding, {M.-H. S.} and Ellegaard, {M. R.} and Allentoft, {M. E.} and Lanigan, {L. T.} and Taurozzi, {A. J.} and Nielsen, {S. Holtsmark} and Dee, {M. W.} and Mortensen, {M. N.} and Christensen, {M. C.} and S{\o}rensen, {S. A.} and Collins, {M. J.} and Gilbert, {M. T. P.} and M. Sikora and S. Rasmussen and H. Schroeder",
year = "2018",
language = "English",
publisher = "bioRxiv",
type = "WorkingPaper",
institution = "bioRxiv",

}

RIS

TY - UNPB

T1 - Stone Age “chewing gum” yields 5,700 yearold human genome and oral microbiome

AU - Jensen, T. Z. T.

AU - Niemann, J.

AU - Iversen, K. Højholt

AU - Fotaki, A. K.

AU - Gopalakrishan, S.

AU - Sinding, M.-H. S.

AU - Ellegaard, M. R.

AU - Allentoft, M. E.

AU - Lanigan, L. T.

AU - Taurozzi, A. J.

AU - Nielsen, S. Holtsmark

AU - Dee, M. W.

AU - Mortensen, M. N.

AU - Christensen, M. C.

AU - Sørensen, S. A.

AU - Collins, M. J.

AU - Gilbert, M. T. P.

AU - Sikora, M.

AU - Rasmussen, S.

AU - Schroeder, H.

PY - 2018

Y1 - 2018

N2 - We present a complete ancient human genome and oral microbiome sequenced from apiece of resinous “chewing gum” recovered from a Stone Age site on the island of Lolland,Denmark, and directly dated to 5,8585,661 cal. BP (GrM13305; 5,007±1 1). We sequenced thegenome to an average depthofcoverage of 2.3× and find that the individual who chewed theresin was female and genetically more closely related to western huntergatherers from mainlandEurope, than huntergatherers from central Scandinavia. We use imputed genotypes to predictphysical characteristics and find that she had dark skin and hair, and blue eyes. Lastly, we alsorecovered microbial DNA that is characteristic of an oral microbiome and faunal reads that likelyassociate with diet. The results highlight the potential for this type of sample material as a newsource of ancient human and microbial DNA.

AB - We present a complete ancient human genome and oral microbiome sequenced from apiece of resinous “chewing gum” recovered from a Stone Age site on the island of Lolland,Denmark, and directly dated to 5,8585,661 cal. BP (GrM13305; 5,007±1 1). We sequenced thegenome to an average depthofcoverage of 2.3× and find that the individual who chewed theresin was female and genetically more closely related to western huntergatherers from mainlandEurope, than huntergatherers from central Scandinavia. We use imputed genotypes to predictphysical characteristics and find that she had dark skin and hair, and blue eyes. Lastly, we alsorecovered microbial DNA that is characteristic of an oral microbiome and faunal reads that likelyassociate with diet. The results highlight the potential for this type of sample material as a newsource of ancient human and microbial DNA.

M3 - Preprint

BT - Stone Age “chewing gum” yields 5,700 yearold human genome and oral microbiome

PB - bioRxiv

ER -

ID: 385901026