The extinct Sicilian wolf shows a complex history of isolation and admixture with ancient dogs

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

The extinct Sicilian wolf shows a complex history of isolation and admixture with ancient dogs. / Ciucani, Marta Maria; Ramos-Madrigal, Jazmín; Hernández-Alonso, Germán; Carmagnini, Alberto; Aninta, Sabhrina Gita; Sun, Xin; Scharff-Olsen, Camilla Hjorth; Lanigan, Liam Thomas; Fracasso, Ilaria; Clausen, Cecilie G.; Aspi, Jouni; Kojola, Ilpo; Baltrūnaitė, Laima; Balčiauskas, Linas; Moore, Jane; Åkesson, Mikael; Saarma, Urmas; Hindrikson, Maris; Hulva, Pavel; Bolfíková, Barbora Černá; Nowak, Carsten; Godinho, Raquel; Smith, Steve; Paule, Ladislav; Nowak, Sabina; Mysłajek, Robert W.; Lo Brutto, Sabrina; Ciucci, Paolo; Boitani, Luigi; Vernesi, Cristiano; Stenøien, Hans K.; Smith, Oliver; Frantz, Laurent; Rossi, Lorenzo; Angelici, Francesco Maria; Cilli, Elisabetta; Sinding, Mikkel Holger S.; Gilbert, M. Thomas P.; Gopalakrishnan, Shyam.

In: iScience, Vol. 26, No. 8, 107307, 2023.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Ciucani, MM, Ramos-Madrigal, J, Hernández-Alonso, G, Carmagnini, A, Aninta, SG, Sun, X, Scharff-Olsen, CH, Lanigan, LT, Fracasso, I, Clausen, CG, Aspi, J, Kojola, I, Baltrūnaitė, L, Balčiauskas, L, Moore, J, Åkesson, M, Saarma, U, Hindrikson, M, Hulva, P, Bolfíková, BČ, Nowak, C, Godinho, R, Smith, S, Paule, L, Nowak, S, Mysłajek, RW, Lo Brutto, S, Ciucci, P, Boitani, L, Vernesi, C, Stenøien, HK, Smith, O, Frantz, L, Rossi, L, Angelici, FM, Cilli, E, Sinding, MHS, Gilbert, MTP & Gopalakrishnan, S 2023, 'The extinct Sicilian wolf shows a complex history of isolation and admixture with ancient dogs', iScience, vol. 26, no. 8, 107307. https://doi.org/10.1016/j.isci.2023.107307

APA

Ciucani, M. M., Ramos-Madrigal, J., Hernández-Alonso, G., Carmagnini, A., Aninta, S. G., Sun, X., Scharff-Olsen, C. H., Lanigan, L. T., Fracasso, I., Clausen, C. G., Aspi, J., Kojola, I., Baltrūnaitė, L., Balčiauskas, L., Moore, J., Åkesson, M., Saarma, U., Hindrikson, M., Hulva, P., ... Gopalakrishnan, S. (2023). The extinct Sicilian wolf shows a complex history of isolation and admixture with ancient dogs. iScience, 26(8), [107307]. https://doi.org/10.1016/j.isci.2023.107307

Vancouver

Ciucani MM, Ramos-Madrigal J, Hernández-Alonso G, Carmagnini A, Aninta SG, Sun X et al. The extinct Sicilian wolf shows a complex history of isolation and admixture with ancient dogs. iScience. 2023;26(8). 107307. https://doi.org/10.1016/j.isci.2023.107307

Author

Ciucani, Marta Maria ; Ramos-Madrigal, Jazmín ; Hernández-Alonso, Germán ; Carmagnini, Alberto ; Aninta, Sabhrina Gita ; Sun, Xin ; Scharff-Olsen, Camilla Hjorth ; Lanigan, Liam Thomas ; Fracasso, Ilaria ; Clausen, Cecilie G. ; Aspi, Jouni ; Kojola, Ilpo ; Baltrūnaitė, Laima ; Balčiauskas, Linas ; Moore, Jane ; Åkesson, Mikael ; Saarma, Urmas ; Hindrikson, Maris ; Hulva, Pavel ; Bolfíková, Barbora Černá ; Nowak, Carsten ; Godinho, Raquel ; Smith, Steve ; Paule, Ladislav ; Nowak, Sabina ; Mysłajek, Robert W. ; Lo Brutto, Sabrina ; Ciucci, Paolo ; Boitani, Luigi ; Vernesi, Cristiano ; Stenøien, Hans K. ; Smith, Oliver ; Frantz, Laurent ; Rossi, Lorenzo ; Angelici, Francesco Maria ; Cilli, Elisabetta ; Sinding, Mikkel Holger S. ; Gilbert, M. Thomas P. ; Gopalakrishnan, Shyam. / The extinct Sicilian wolf shows a complex history of isolation and admixture with ancient dogs. In: iScience. 2023 ; Vol. 26, No. 8.

Bibtex

@article{c6ef927d98cc4b9d89722f0ddb399b10,
title = "The extinct Sicilian wolf shows a complex history of isolation and admixture with ancient dogs",
abstract = "The Sicilian wolf remained isolated in Sicily from the end of the Pleistocene until its extermination in the 1930s–1960s. Given its long-term isolation on the island and distinctive morphology, the genetic origin of the Sicilian wolf remains debated. We sequenced four nuclear genomes and five mitogenomes from the seven existing museum specimens to investigate the Sicilian wolf ancestry, relationships with extant and extinct wolves and dogs, and diversity. Our results show that the Sicilian wolf is most closely related to the Italian wolf but carries ancestry from a lineage related to European Eneolithic and Bronze Age dogs. The average nucleotide diversity of the Sicilian wolf was half of the Italian wolf, with 37–50% of its genome contained in runs of homozygosity. Overall, we show that, by the time it went extinct, the Sicilian wolf had high inbreeding and low-genetic diversity, consistent with a population in an insular environment.",
keywords = "Canine genetics, Evolutionary biology",
author = "Ciucani, {Marta Maria} and Jazm{\'i}n Ramos-Madrigal and Germ{\'a}n Hern{\'a}ndez-Alonso and Alberto Carmagnini and Aninta, {Sabhrina Gita} and Xin Sun and Scharff-Olsen, {Camilla Hjorth} and Lanigan, {Liam Thomas} and Ilaria Fracasso and Clausen, {Cecilie G.} and Jouni Aspi and Ilpo Kojola and Laima Baltrūnaitė and Linas Bal{\v c}iauskas and Jane Moore and Mikael {\AA}kesson and Urmas Saarma and Maris Hindrikson and Pavel Hulva and Bolf{\'i}kov{\'a}, {Barbora {\v C}ern{\'a}} and Carsten Nowak and Raquel Godinho and Steve Smith and Ladislav Paule and Sabina Nowak and Mys{\l}ajek, {Robert W.} and {Lo Brutto}, Sabrina and Paolo Ciucci and Luigi Boitani and Cristiano Vernesi and Sten{\o}ien, {Hans K.} and Oliver Smith and Laurent Frantz and Lorenzo Rossi and Angelici, {Francesco Maria} and Elisabetta Cilli and Sinding, {Mikkel Holger S.} and Gilbert, {M. Thomas P.} and Shyam Gopalakrishnan",
note = "Publisher Copyright: {\textcopyright} 2023 The Authors",
year = "2023",
doi = "10.1016/j.isci.2023.107307",
language = "English",
volume = "26",
journal = "iScience",
issn = "2589-0042",
publisher = "Elsevier",
number = "8",

}

RIS

TY - JOUR

T1 - The extinct Sicilian wolf shows a complex history of isolation and admixture with ancient dogs

AU - Ciucani, Marta Maria

AU - Ramos-Madrigal, Jazmín

AU - Hernández-Alonso, Germán

AU - Carmagnini, Alberto

AU - Aninta, Sabhrina Gita

AU - Sun, Xin

AU - Scharff-Olsen, Camilla Hjorth

AU - Lanigan, Liam Thomas

AU - Fracasso, Ilaria

AU - Clausen, Cecilie G.

AU - Aspi, Jouni

AU - Kojola, Ilpo

AU - Baltrūnaitė, Laima

AU - Balčiauskas, Linas

AU - Moore, Jane

AU - Åkesson, Mikael

AU - Saarma, Urmas

AU - Hindrikson, Maris

AU - Hulva, Pavel

AU - Bolfíková, Barbora Černá

AU - Nowak, Carsten

AU - Godinho, Raquel

AU - Smith, Steve

AU - Paule, Ladislav

AU - Nowak, Sabina

AU - Mysłajek, Robert W.

AU - Lo Brutto, Sabrina

AU - Ciucci, Paolo

AU - Boitani, Luigi

AU - Vernesi, Cristiano

AU - Stenøien, Hans K.

AU - Smith, Oliver

AU - Frantz, Laurent

AU - Rossi, Lorenzo

AU - Angelici, Francesco Maria

AU - Cilli, Elisabetta

AU - Sinding, Mikkel Holger S.

AU - Gilbert, M. Thomas P.

AU - Gopalakrishnan, Shyam

N1 - Publisher Copyright: © 2023 The Authors

PY - 2023

Y1 - 2023

N2 - The Sicilian wolf remained isolated in Sicily from the end of the Pleistocene until its extermination in the 1930s–1960s. Given its long-term isolation on the island and distinctive morphology, the genetic origin of the Sicilian wolf remains debated. We sequenced four nuclear genomes and five mitogenomes from the seven existing museum specimens to investigate the Sicilian wolf ancestry, relationships with extant and extinct wolves and dogs, and diversity. Our results show that the Sicilian wolf is most closely related to the Italian wolf but carries ancestry from a lineage related to European Eneolithic and Bronze Age dogs. The average nucleotide diversity of the Sicilian wolf was half of the Italian wolf, with 37–50% of its genome contained in runs of homozygosity. Overall, we show that, by the time it went extinct, the Sicilian wolf had high inbreeding and low-genetic diversity, consistent with a population in an insular environment.

AB - The Sicilian wolf remained isolated in Sicily from the end of the Pleistocene until its extermination in the 1930s–1960s. Given its long-term isolation on the island and distinctive morphology, the genetic origin of the Sicilian wolf remains debated. We sequenced four nuclear genomes and five mitogenomes from the seven existing museum specimens to investigate the Sicilian wolf ancestry, relationships with extant and extinct wolves and dogs, and diversity. Our results show that the Sicilian wolf is most closely related to the Italian wolf but carries ancestry from a lineage related to European Eneolithic and Bronze Age dogs. The average nucleotide diversity of the Sicilian wolf was half of the Italian wolf, with 37–50% of its genome contained in runs of homozygosity. Overall, we show that, by the time it went extinct, the Sicilian wolf had high inbreeding and low-genetic diversity, consistent with a population in an insular environment.

KW - Canine genetics

KW - Evolutionary biology

U2 - 10.1016/j.isci.2023.107307

DO - 10.1016/j.isci.2023.107307

M3 - Journal article

C2 - 37559898

AN - SCOPUS:85165972998

VL - 26

JO - iScience

JF - iScience

SN - 2589-0042

IS - 8

M1 - 107307

ER -

ID: 361702307