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The genomic landscape of Mexican Indigenous populations brings insights into the peopling of the Americas. / García-Ortiz, Humberto; Barajas-Olmos, Francisco; Contreras-Cubas, Cecilia; Cid-Soto, Miguel Ángel; Córdova, Emilio J.; Centeno-Cruz, Federico; Mendoza-Caamal, Elvia; Cicerón-Arellano, Isabel; Flores-Huacuja, Marlen; Baca, Paulina; Bolnick, Deborah A.; Snow, Meradeth; Flores-Martínez, Silvia Esperanza; Ortiz-Lopez, Rocio; Reynolds, Austin W.; Blanchet, Antonio; Morales-Marín, Mirna; Velázquez-Cruz, Rafael; Kostic, Aleksandar David; Galaviz-Hernández, Carlos; García-Zapién, Alejandra Guadalupe; Jiménez-López, José Concepción; León-Reyes, Guadalupe; Salas-Bautista, Eva Gabriela; Lazalde-Ramos, Blanca Patricia; Jiménez-Ruíz, Juan Luis; Salas-Martínez, Guadalupe; Ramos-Madrigal, Jazmín; Mirzaeicheshmeh, Elaheh; Saldaña-Alvarez, Yolanda; del Carmen Abrahantes-Pérez, María; Loeza-Becerra, Francisco; Mojica-Espinosa, Raúl; Sánchez-Quinto, Federico; Rangel-Villalobos, Héctor; Sosa-Macías, Martha; Sánchez-Corona, José; Rojas-Martinez, Augusto; Martínez-Hernández, Angélica; Orozco, Lorena.
In:
Nature Communications, Vol. 12, 5942, 2021.
Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
García-Ortiz, H, Barajas-Olmos, F, Contreras-Cubas, C, Cid-Soto, MÁ, Córdova, EJ, Centeno-Cruz, F, Mendoza-Caamal, E, Cicerón-Arellano, I, Flores-Huacuja, M, Baca, P, Bolnick, DA, Snow, M, Flores-Martínez, SE, Ortiz-Lopez, R, Reynolds, AW, Blanchet, A, Morales-Marín, M, Velázquez-Cruz, R, Kostic, AD, Galaviz-Hernández, C, García-Zapién, AG, Jiménez-López, JC, León-Reyes, G, Salas-Bautista, EG, Lazalde-Ramos, BP, Jiménez-Ruíz, JL, Salas-Martínez, G
, Ramos-Madrigal, J, Mirzaeicheshmeh, E, Saldaña-Alvarez, Y, del Carmen Abrahantes-Pérez, M, Loeza-Becerra, F, Mojica-Espinosa, R, Sánchez-Quinto, F, Rangel-Villalobos, H, Sosa-Macías, M, Sánchez-Corona, J, Rojas-Martinez, A, Martínez-Hernández, A & Orozco, L 2021, '
The genomic landscape of Mexican Indigenous populations brings insights into the peopling of the Americas',
Nature Communications, vol. 12, 5942.
https://doi.org/10.1038/s41467-021-26188-wAPA
García-Ortiz, H., Barajas-Olmos, F., Contreras-Cubas, C., Cid-Soto, M. Á., Córdova, E. J., Centeno-Cruz, F., Mendoza-Caamal, E., Cicerón-Arellano, I., Flores-Huacuja, M., Baca, P., Bolnick, D. A., Snow, M., Flores-Martínez, S. E., Ortiz-Lopez, R., Reynolds, A. W., Blanchet, A., Morales-Marín, M., Velázquez-Cruz, R., Kostic, A. D., ... Orozco, L. (2021).
The genomic landscape of Mexican Indigenous populations brings insights into the peopling of the Americas.
Nature Communications,
12, [5942].
https://doi.org/10.1038/s41467-021-26188-wVancouver
García-Ortiz H, Barajas-Olmos F, Contreras-Cubas C, Cid-Soto MÁ, Córdova EJ, Centeno-Cruz F et al.
The genomic landscape of Mexican Indigenous populations brings insights into the peopling of the Americas.
Nature Communications. 2021;12. 5942.
https://doi.org/10.1038/s41467-021-26188-wAuthor
García-Ortiz, Humberto ; Barajas-Olmos, Francisco ; Contreras-Cubas, Cecilia ; Cid-Soto, Miguel Ángel ; Córdova, Emilio J. ; Centeno-Cruz, Federico ; Mendoza-Caamal, Elvia ; Cicerón-Arellano, Isabel ; Flores-Huacuja, Marlen ; Baca, Paulina ; Bolnick, Deborah A. ; Snow, Meradeth ; Flores-Martínez, Silvia Esperanza ; Ortiz-Lopez, Rocio ; Reynolds, Austin W. ; Blanchet, Antonio ; Morales-Marín, Mirna ; Velázquez-Cruz, Rafael ; Kostic, Aleksandar David ; Galaviz-Hernández, Carlos ; García-Zapién, Alejandra Guadalupe ; Jiménez-López, José Concepción ; León-Reyes, Guadalupe ; Salas-Bautista, Eva Gabriela ; Lazalde-Ramos, Blanca Patricia ; Jiménez-Ruíz, Juan Luis ; Salas-Martínez, Guadalupe ; Ramos-Madrigal, Jazmín ; Mirzaeicheshmeh, Elaheh ; Saldaña-Alvarez, Yolanda ; del Carmen Abrahantes-Pérez, María ; Loeza-Becerra, Francisco ; Mojica-Espinosa, Raúl ; Sánchez-Quinto, Federico ; Rangel-Villalobos, Héctor ; Sosa-Macías, Martha ; Sánchez-Corona, José ; Rojas-Martinez, Augusto ; Martínez-Hernández, Angélica ; Orozco, Lorena. / The genomic landscape of Mexican Indigenous populations brings insights into the peopling of the Americas. In: Nature Communications. 2021 ; Vol. 12.
Bibtex
@article{12ff1dd80cd842c2aed5b8abc078955d,
title = "The genomic landscape of Mexican Indigenous populations brings insights into the peopling of the Americas",
abstract = "The genetic makeup of Indigenous populations inhabiting Mexico has been strongly influenced by geography and demographic history. Here, we perform a genome-wide analysis of 716 newly genotyped individuals from 60 of the 68 recognized ethnic groups in Mexico. We show that the genetic structure of these populations is strongly influenced by geography, and our demographic reconstructions suggest a decline in the population size of all tested populations in the last 15–30 generations. We find evidence that Aridoamerican and Mesoamerican populations diverged roughly 4–9.9 ka, around the time when sedentary farming started in Mesoamerica. Comparisons with ancient genomes indicate that the Upward Sun River 1 (USR1) individual is an outgroup to Mexican/South American Indigenous populations, whereas Anzick-1 was more closely related to Mesoamerican/South American populations than to those from Aridoamerica, showing an even more complex history of divergence than recognized so far.",
author = "Humberto Garc{\'i}a-Ortiz and Francisco Barajas-Olmos and Cecilia Contreras-Cubas and Cid-Soto, {Miguel {\'A}ngel} and C{\'o}rdova, {Emilio J.} and Federico Centeno-Cruz and Elvia Mendoza-Caamal and Isabel Cicer{\'o}n-Arellano and Marlen Flores-Huacuja and Paulina Baca and Bolnick, {Deborah A.} and Meradeth Snow and Flores-Mart{\'i}nez, {Silvia Esperanza} and Rocio Ortiz-Lopez and Reynolds, {Austin W.} and Antonio Blanchet and Mirna Morales-Mar{\'i}n and Rafael Vel{\'a}zquez-Cruz and Kostic, {Aleksandar David} and Carlos Galaviz-Hern{\'a}ndez and Garc{\'i}a-Zapi{\'e}n, {Alejandra Guadalupe} and Jim{\'e}nez-L{\'o}pez, {Jos{\'e} Concepci{\'o}n} and Guadalupe Le{\'o}n-Reyes and Salas-Bautista, {Eva Gabriela} and Lazalde-Ramos, {Blanca Patricia} and Jim{\'e}nez-Ru{\'i}z, {Juan Luis} and Guadalupe Salas-Mart{\'i}nez and Jazm{\'i}n Ramos-Madrigal and Elaheh Mirzaeicheshmeh and Yolanda Salda{\~n}a-Alvarez and {del Carmen Abrahantes-P{\'e}rez}, Mar{\'i}a and Francisco Loeza-Becerra and Ra{\'u}l Mojica-Espinosa and Federico S{\'a}nchez-Quinto and H{\'e}ctor Rangel-Villalobos and Martha Sosa-Mac{\'i}as and Jos{\'e} S{\'a}nchez-Corona and Augusto Rojas-Martinez and Ang{\'e}lica Mart{\'i}nez-Hern{\'a}ndez and Lorena Orozco",
note = "Publisher Copyright: {\textcopyright} 2021, The Author(s).",
year = "2021",
doi = "10.1038/s41467-021-26188-w",
language = "English",
volume = "12",
journal = "Nature Communications",
issn = "2041-1723",
publisher = "nature publishing group",
}
RIS
TY - JOUR
T1 - The genomic landscape of Mexican Indigenous populations brings insights into the peopling of the Americas
AU - García-Ortiz, Humberto
AU - Barajas-Olmos, Francisco
AU - Contreras-Cubas, Cecilia
AU - Cid-Soto, Miguel Ángel
AU - Córdova, Emilio J.
AU - Centeno-Cruz, Federico
AU - Mendoza-Caamal, Elvia
AU - Cicerón-Arellano, Isabel
AU - Flores-Huacuja, Marlen
AU - Baca, Paulina
AU - Bolnick, Deborah A.
AU - Snow, Meradeth
AU - Flores-Martínez, Silvia Esperanza
AU - Ortiz-Lopez, Rocio
AU - Reynolds, Austin W.
AU - Blanchet, Antonio
AU - Morales-Marín, Mirna
AU - Velázquez-Cruz, Rafael
AU - Kostic, Aleksandar David
AU - Galaviz-Hernández, Carlos
AU - García-Zapién, Alejandra Guadalupe
AU - Jiménez-López, José Concepción
AU - León-Reyes, Guadalupe
AU - Salas-Bautista, Eva Gabriela
AU - Lazalde-Ramos, Blanca Patricia
AU - Jiménez-Ruíz, Juan Luis
AU - Salas-Martínez, Guadalupe
AU - Ramos-Madrigal, Jazmín
AU - Mirzaeicheshmeh, Elaheh
AU - Saldaña-Alvarez, Yolanda
AU - del Carmen Abrahantes-Pérez, María
AU - Loeza-Becerra, Francisco
AU - Mojica-Espinosa, Raúl
AU - Sánchez-Quinto, Federico
AU - Rangel-Villalobos, Héctor
AU - Sosa-Macías, Martha
AU - Sánchez-Corona, José
AU - Rojas-Martinez, Augusto
AU - Martínez-Hernández, Angélica
AU - Orozco, Lorena
N1 - Publisher Copyright:
© 2021, The Author(s).
PY - 2021
Y1 - 2021
N2 - The genetic makeup of Indigenous populations inhabiting Mexico has been strongly influenced by geography and demographic history. Here, we perform a genome-wide analysis of 716 newly genotyped individuals from 60 of the 68 recognized ethnic groups in Mexico. We show that the genetic structure of these populations is strongly influenced by geography, and our demographic reconstructions suggest a decline in the population size of all tested populations in the last 15–30 generations. We find evidence that Aridoamerican and Mesoamerican populations diverged roughly 4–9.9 ka, around the time when sedentary farming started in Mesoamerica. Comparisons with ancient genomes indicate that the Upward Sun River 1 (USR1) individual is an outgroup to Mexican/South American Indigenous populations, whereas Anzick-1 was more closely related to Mesoamerican/South American populations than to those from Aridoamerica, showing an even more complex history of divergence than recognized so far.
AB - The genetic makeup of Indigenous populations inhabiting Mexico has been strongly influenced by geography and demographic history. Here, we perform a genome-wide analysis of 716 newly genotyped individuals from 60 of the 68 recognized ethnic groups in Mexico. We show that the genetic structure of these populations is strongly influenced by geography, and our demographic reconstructions suggest a decline in the population size of all tested populations in the last 15–30 generations. We find evidence that Aridoamerican and Mesoamerican populations diverged roughly 4–9.9 ka, around the time when sedentary farming started in Mesoamerica. Comparisons with ancient genomes indicate that the Upward Sun River 1 (USR1) individual is an outgroup to Mexican/South American Indigenous populations, whereas Anzick-1 was more closely related to Mesoamerican/South American populations than to those from Aridoamerica, showing an even more complex history of divergence than recognized so far.
U2 - 10.1038/s41467-021-26188-w
DO - 10.1038/s41467-021-26188-w
M3 - Journal article
C2 - 34642312
AN - SCOPUS:85117232577
VL - 12
JO - Nature Communications
JF - Nature Communications
SN - 2041-1723
M1 - 5942
ER -
