The gut microbiome buffers dietary adaptation in Bronze Age domesticated dogs

Research output: Contribution to journal › Journal article › Research › peer-review

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The gut microbiome buffers dietary adaptation in Bronze Age domesticated dogs. / Rampelli, Simone; Turroni, Silvia; Debandi, Florencia; Alberdi, Antton; Schnorr, Stephanie L.; Hofman, Courtney A.; Taddia, Alberto; Helg, Riccardo; Biagi, Elena; Brigidi, Patrizia; D'Amico, Federica; Cattani, Maurizio; Candela, Marco.

In: iScience, Vol. 24, No. 8, 102816, 2021.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Rampelli, S, Turroni, S, Debandi, F, Alberdi, A, Schnorr, SL, Hofman, CA, Taddia, A, Helg, R, Biagi, E, Brigidi, P, D'Amico, F, Cattani, M & Candela, M 2021, 'The gut microbiome buffers dietary adaptation in Bronze Age domesticated dogs', iScience, vol. 24, no. 8, 102816. https://doi.org/10.1016/j.isci.2021.102816

APA

Rampelli, S., Turroni, S., Debandi, F., Alberdi, A., Schnorr, S. L., Hofman, C. A., Taddia, A., Helg, R., Biagi, E., Brigidi, P., D'Amico, F., Cattani, M., & Candela, M. (2021). The gut microbiome buffers dietary adaptation in Bronze Age domesticated dogs. iScience, 24(8), [102816]. https://doi.org/10.1016/j.isci.2021.102816

Vancouver

Rampelli S, Turroni S, Debandi F, Alberdi A, Schnorr SL, Hofman CA et al. The gut microbiome buffers dietary adaptation in Bronze Age domesticated dogs. iScience. 2021;24(8). 102816. https://doi.org/10.1016/j.isci.2021.102816

Author

Rampelli, Simone ; Turroni, Silvia ; Debandi, Florencia ; Alberdi, Antton ; Schnorr, Stephanie L. ; Hofman, Courtney A. ; Taddia, Alberto ; Helg, Riccardo ; Biagi, Elena ; Brigidi, Patrizia ; D'Amico, Federica ; Cattani, Maurizio ; Candela, Marco. / The gut microbiome buffers dietary adaptation in Bronze Age domesticated dogs. In: iScience. 2021 ; Vol. 24, No. 8.

Bibtex

@article{861c6f348219409fbe5abe54f4aaafd3,
title = "The gut microbiome buffers dietary adaptation in Bronze Age domesticated dogs",
abstract = "In an attempt to explore the role of the gut microbiome during recent canine evolutionary history, we sequenced the metagenome of 13 canine coprolites dated ca. 3,600–3,450 years ago from the Bronze Age archaeological site of Solarolo (Italy), which housed a complex farming community. The microbiome structure of Solarolo dogs revealed continuity with that of modern dogs, but it also shared some features with the wild wolf microbiome, as a kind of transitional state between them. The dietary niche, as also inferred from the microbiome composition, was omnivorous, with evidence of consumption of starchy agricultural foods. Of interest, the Solarolo dog microbiome was particularly enriched in sequences encoding alpha-amylases and complemented a low copy number of the host amylase gene. These findings suggest that Neolithic dogs could have responded to the transition to a starch-rich diet by expanding microbial functionalities devoted to starch catabolism, thus compensating for delayed host response.",
keywords = "biological sciences, evolutionary biology, evolutionary history, evolutionary processes, genomic analysis, genomics, microbiome, omics, Phylogenetics, phylogeny, sequence analysis",
author = "Simone Rampelli and Silvia Turroni and Florencia Debandi and Antton Alberdi and Schnorr, {Stephanie L.} and Hofman, {Courtney A.} and Alberto Taddia and Riccardo Helg and Elena Biagi and Patrizia Brigidi and Federica D'Amico and Maurizio Cattani and Marco Candela",
note = "Publisher Copyright: {\textcopyright} 2021 The Authors",
year = "2021",
doi = "10.1016/j.isci.2021.102816",
language = "English",
volume = "24",
journal = "iScience",
issn = "2589-0042",
publisher = "Elsevier",
number = "8",

}

RIS

TY - JOUR

T1 - The gut microbiome buffers dietary adaptation in Bronze Age domesticated dogs

AU - Rampelli, Simone

AU - Turroni, Silvia

AU - Debandi, Florencia

AU - Alberdi, Antton

AU - Schnorr, Stephanie L.

AU - Hofman, Courtney A.

AU - Taddia, Alberto

AU - Helg, Riccardo

AU - Biagi, Elena

AU - Brigidi, Patrizia

AU - D'Amico, Federica

AU - Cattani, Maurizio

AU - Candela, Marco

N1 - Publisher Copyright: © 2021 The Authors

PY - 2021

Y1 - 2021

N2 - In an attempt to explore the role of the gut microbiome during recent canine evolutionary history, we sequenced the metagenome of 13 canine coprolites dated ca. 3,600–3,450 years ago from the Bronze Age archaeological site of Solarolo (Italy), which housed a complex farming community. The microbiome structure of Solarolo dogs revealed continuity with that of modern dogs, but it also shared some features with the wild wolf microbiome, as a kind of transitional state between them. The dietary niche, as also inferred from the microbiome composition, was omnivorous, with evidence of consumption of starchy agricultural foods. Of interest, the Solarolo dog microbiome was particularly enriched in sequences encoding alpha-amylases and complemented a low copy number of the host amylase gene. These findings suggest that Neolithic dogs could have responded to the transition to a starch-rich diet by expanding microbial functionalities devoted to starch catabolism, thus compensating for delayed host response.

AB - In an attempt to explore the role of the gut microbiome during recent canine evolutionary history, we sequenced the metagenome of 13 canine coprolites dated ca. 3,600–3,450 years ago from the Bronze Age archaeological site of Solarolo (Italy), which housed a complex farming community. The microbiome structure of Solarolo dogs revealed continuity with that of modern dogs, but it also shared some features with the wild wolf microbiome, as a kind of transitional state between them. The dietary niche, as also inferred from the microbiome composition, was omnivorous, with evidence of consumption of starchy agricultural foods. Of interest, the Solarolo dog microbiome was particularly enriched in sequences encoding alpha-amylases and complemented a low copy number of the host amylase gene. These findings suggest that Neolithic dogs could have responded to the transition to a starch-rich diet by expanding microbial functionalities devoted to starch catabolism, thus compensating for delayed host response.

KW - biological sciences

KW - evolutionary biology

KW - evolutionary history

KW - evolutionary processes

KW - genomic analysis

KW - genomics

KW - microbiome

KW - omics

KW - Phylogenetics

KW - phylogeny

KW - sequence analysis

U2 - 10.1016/j.isci.2021.102816

DO - 10.1016/j.isci.2021.102816

M3 - Journal article

C2 - 34377966

AN - SCOPUS:85111299312

VL - 24

JO - iScience

JF - iScience

SN - 2589-0042

IS - 8

M1 - 102816

ER -

ID: 276270354