The impact of founder events on chromosomal variability in multiply mating species

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The impact of founder events on chromosomal variability in multiply mating species. / Pool, John E; Nielsen, Rasmus.

In: Molecular Biology and Evolution, Vol. 25, No. 8, 2008, p. 1728-36.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Pool, JE & Nielsen, R 2008, 'The impact of founder events on chromosomal variability in multiply mating species', Molecular Biology and Evolution, vol. 25, no. 8, pp. 1728-36. https://doi.org/10.1093/molbev/msn124

APA

Pool, J. E., & Nielsen, R. (2008). The impact of founder events on chromosomal variability in multiply mating species. Molecular Biology and Evolution, 25(8), 1728-36. https://doi.org/10.1093/molbev/msn124

Vancouver

Pool JE, Nielsen R. The impact of founder events on chromosomal variability in multiply mating species. Molecular Biology and Evolution. 2008;25(8):1728-36. https://doi.org/10.1093/molbev/msn124

Author

Pool, John E ; Nielsen, Rasmus. / The impact of founder events on chromosomal variability in multiply mating species. In: Molecular Biology and Evolution. 2008 ; Vol. 25, No. 8. pp. 1728-36.

Bibtex

@article{e87cda70e6f711ddbf70000ea68e967b,
title = "The impact of founder events on chromosomal variability in multiply mating species",
abstract = "In species with heterogametic males, the relative levels of X chromosome versus autosome diversity hold key information about the evolutionary forces at work in a population. It has been shown that population size changes alter the ratio of X linked to autosomal (X/A) variation, with population size reductions and recent bottlenecks leading to decreased X/A diversity ratios. Here we use theory and simulation to investigate a separate demographic effect-that of founder events involving multiply mated females-and find that it leads to much stronger reductions in X/A diversity ratios than are produced by simple population size changes. Investigating the potential of this process to account for sharply reduced X-linked diversity in European Drosophila melanogaster, we find that this model yields predictions that are compatible with the empirical data.",
author = "Pool, {John E} and Rasmus Nielsen",
note = "Keywords: Animals; Chromosomes; Computer Simulation; Drosophila melanogaster; Female; Founder Effect; Genes, X-Linked; Genetic Variation; Genetics, Population; Models, Genetic; Sexual Behavior, Animal",
year = "2008",
doi = "10.1093/molbev/msn124",
language = "English",
volume = "25",
pages = "1728--36",
journal = "Molecular Biology and Evolution",
issn = "0737-4038",
publisher = "Oxford University Press",
number = "8",

}

RIS

TY - JOUR

T1 - The impact of founder events on chromosomal variability in multiply mating species

AU - Pool, John E

AU - Nielsen, Rasmus

N1 - Keywords: Animals; Chromosomes; Computer Simulation; Drosophila melanogaster; Female; Founder Effect; Genes, X-Linked; Genetic Variation; Genetics, Population; Models, Genetic; Sexual Behavior, Animal

PY - 2008

Y1 - 2008

N2 - In species with heterogametic males, the relative levels of X chromosome versus autosome diversity hold key information about the evolutionary forces at work in a population. It has been shown that population size changes alter the ratio of X linked to autosomal (X/A) variation, with population size reductions and recent bottlenecks leading to decreased X/A diversity ratios. Here we use theory and simulation to investigate a separate demographic effect-that of founder events involving multiply mated females-and find that it leads to much stronger reductions in X/A diversity ratios than are produced by simple population size changes. Investigating the potential of this process to account for sharply reduced X-linked diversity in European Drosophila melanogaster, we find that this model yields predictions that are compatible with the empirical data.

AB - In species with heterogametic males, the relative levels of X chromosome versus autosome diversity hold key information about the evolutionary forces at work in a population. It has been shown that population size changes alter the ratio of X linked to autosomal (X/A) variation, with population size reductions and recent bottlenecks leading to decreased X/A diversity ratios. Here we use theory and simulation to investigate a separate demographic effect-that of founder events involving multiply mated females-and find that it leads to much stronger reductions in X/A diversity ratios than are produced by simple population size changes. Investigating the potential of this process to account for sharply reduced X-linked diversity in European Drosophila melanogaster, we find that this model yields predictions that are compatible with the empirical data.

U2 - 10.1093/molbev/msn124

DO - 10.1093/molbev/msn124

M3 - Journal article

C2 - 18511425

VL - 25

SP - 1728

EP - 1736

JO - Molecular Biology and Evolution

JF - Molecular Biology and Evolution

SN - 0737-4038

IS - 8

ER -

ID: 9856332