The Tibetan-Yi region is both a corridor and a barrier for human gene flow

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Standard

The Tibetan-Yi region is both a corridor and a barrier for human gene flow. / Zhang, Zhe; Zhang, Yanlin; Wang, Yinan; Zhao, Zicheng; Yang, Melinda; Zhang, Lin; Zhou, Bin; Xu, Bingying; Zhang, Hongbo; Chen, Teng; Dai, Wenkui; Zhou, Yong; Shi, Shuo; Nielsen, Rasmus; Li, Shuai Cheng; Li, Shengbin.

In: Cell Reports, Vol. 39, No. 4, 110720, 2022.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Zhang, Z, Zhang, Y, Wang, Y, Zhao, Z, Yang, M, Zhang, L, Zhou, B, Xu, B, Zhang, H, Chen, T, Dai, W, Zhou, Y, Shi, S, Nielsen, R, Li, SC & Li, S 2022, 'The Tibetan-Yi region is both a corridor and a barrier for human gene flow', Cell Reports, vol. 39, no. 4, 110720. https://doi.org/10.1016/j.celrep.2022.110720

APA

Zhang, Z., Zhang, Y., Wang, Y., Zhao, Z., Yang, M., Zhang, L., Zhou, B., Xu, B., Zhang, H., Chen, T., Dai, W., Zhou, Y., Shi, S., Nielsen, R., Li, S. C., & Li, S. (2022). The Tibetan-Yi region is both a corridor and a barrier for human gene flow. Cell Reports, 39(4), [110720]. https://doi.org/10.1016/j.celrep.2022.110720

Vancouver

Zhang Z, Zhang Y, Wang Y, Zhao Z, Yang M, Zhang L et al. The Tibetan-Yi region is both a corridor and a barrier for human gene flow. Cell Reports. 2022;39(4). 110720. https://doi.org/10.1016/j.celrep.2022.110720

Author

Zhang, Zhe ; Zhang, Yanlin ; Wang, Yinan ; Zhao, Zicheng ; Yang, Melinda ; Zhang, Lin ; Zhou, Bin ; Xu, Bingying ; Zhang, Hongbo ; Chen, Teng ; Dai, Wenkui ; Zhou, Yong ; Shi, Shuo ; Nielsen, Rasmus ; Li, Shuai Cheng ; Li, Shengbin. / The Tibetan-Yi region is both a corridor and a barrier for human gene flow. In: Cell Reports. 2022 ; Vol. 39, No. 4.

Bibtex

@article{fd7cd8bbe9684876bd22f8903b0c1c78,
title = "The Tibetan-Yi region is both a corridor and a barrier for human gene flow",
abstract = "The Tibetan-Yi Corridor (TYC) region between Tibet and the rest of east Asia has served as a crossroads for human migrations for thousands of years. The lack of whole-genome sequencing data specific to the TYC populations has hindered the understanding of the fundamental patterns of migration and divergence between humans in east Asia and southeast Asia. Here, we provide 248 individual whole genomes from the 16 TYC and 3 outgroup populations to elucidate historical relationships. We find that the Tibetan plateau forms an important barrier to gene flow, with a more Tibetan-like ancestry in northern populations and a southern east Asian-related ancestry in south populations. An isolated population, Achang, shows a prolonged isolation and genetic drift compared to other TYC populations. We also note that previous claims regarding the history and structure of TYC populations inferred by linguistics are incompatible with the genetic evidence.",
keywords = "CP: Molecular biology, geographic patterns, human migration, population genetics, Tibetan-Yi corridor",
author = "Zhe Zhang and Yanlin Zhang and Yinan Wang and Zicheng Zhao and Melinda Yang and Lin Zhang and Bin Zhou and Bingying Xu and Hongbo Zhang and Teng Chen and Wenkui Dai and Yong Zhou and Shuo Shi and Rasmus Nielsen and Li, {Shuai Cheng} and Shengbin Li",
note = "Publisher Copyright: {\textcopyright} 2022 The Author(s)",
year = "2022",
doi = "10.1016/j.celrep.2022.110720",
language = "English",
volume = "39",
journal = "Cell Reports",
issn = "2211-1247",
publisher = "Cell Press",
number = "4",

}

RIS

TY - JOUR

T1 - The Tibetan-Yi region is both a corridor and a barrier for human gene flow

AU - Zhang, Zhe

AU - Zhang, Yanlin

AU - Wang, Yinan

AU - Zhao, Zicheng

AU - Yang, Melinda

AU - Zhang, Lin

AU - Zhou, Bin

AU - Xu, Bingying

AU - Zhang, Hongbo

AU - Chen, Teng

AU - Dai, Wenkui

AU - Zhou, Yong

AU - Shi, Shuo

AU - Nielsen, Rasmus

AU - Li, Shuai Cheng

AU - Li, Shengbin

N1 - Publisher Copyright: © 2022 The Author(s)

PY - 2022

Y1 - 2022

N2 - The Tibetan-Yi Corridor (TYC) region between Tibet and the rest of east Asia has served as a crossroads for human migrations for thousands of years. The lack of whole-genome sequencing data specific to the TYC populations has hindered the understanding of the fundamental patterns of migration and divergence between humans in east Asia and southeast Asia. Here, we provide 248 individual whole genomes from the 16 TYC and 3 outgroup populations to elucidate historical relationships. We find that the Tibetan plateau forms an important barrier to gene flow, with a more Tibetan-like ancestry in northern populations and a southern east Asian-related ancestry in south populations. An isolated population, Achang, shows a prolonged isolation and genetic drift compared to other TYC populations. We also note that previous claims regarding the history and structure of TYC populations inferred by linguistics are incompatible with the genetic evidence.

AB - The Tibetan-Yi Corridor (TYC) region between Tibet and the rest of east Asia has served as a crossroads for human migrations for thousands of years. The lack of whole-genome sequencing data specific to the TYC populations has hindered the understanding of the fundamental patterns of migration and divergence between humans in east Asia and southeast Asia. Here, we provide 248 individual whole genomes from the 16 TYC and 3 outgroup populations to elucidate historical relationships. We find that the Tibetan plateau forms an important barrier to gene flow, with a more Tibetan-like ancestry in northern populations and a southern east Asian-related ancestry in south populations. An isolated population, Achang, shows a prolonged isolation and genetic drift compared to other TYC populations. We also note that previous claims regarding the history and structure of TYC populations inferred by linguistics are incompatible with the genetic evidence.

KW - CP: Molecular biology

KW - geographic patterns

KW - human migration

KW - population genetics

KW - Tibetan-Yi corridor

U2 - 10.1016/j.celrep.2022.110720

DO - 10.1016/j.celrep.2022.110720

M3 - Journal article

C2 - 35476999

AN - SCOPUS:85128943290

VL - 39

JO - Cell Reports

JF - Cell Reports

SN - 2211-1247

IS - 4

M1 - 110720

ER -

ID: 341479747