Real-time genomics for One Health

Research output: Contribution to journal › Review › Research › peer-review

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Real-time genomics for One Health. / Urban, Lara; Perlas, Albert; Francino, Olga; Martí-Carreras, Joan; Muga, Brenda A.; Mwangi, Jenniffer W.; Boykin Okalebo, Laura; Stanton, Jo-Ann L.; Black, Amanda; Waipara, Nick; Fontsere, Claudia; Eccles, David; Urel, Harika; Reska, Tim; Morales, Hernán E.; Palmada-Flores, Marc; Marques-Bonet, Tomas; Watsa, Mrinalini; Libke, Zane; Erkenswick, Gideon; van Oosterhout, Cock.

In: Molecular Systems Biology, Vol. 19, No. 8, e11686, 2023.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Urban, L, Perlas, A, Francino, O, Martí-Carreras, J, Muga, BA, Mwangi, JW, Boykin Okalebo, L, Stanton, J-AL, Black, A, Waipara, N, Fontsere, C, Eccles, D, Urel, H, Reska, T, Morales, HE, Palmada-Flores, M, Marques-Bonet, T, Watsa, M, Libke, Z, Erkenswick, G & van Oosterhout, C 2023, 'Real-time genomics for One Health', Molecular Systems Biology, vol. 19, no. 8, e11686. https://doi.org/10.15252/msb.202311686

APA

Urban, L., Perlas, A., Francino, O., Martí-Carreras, J., Muga, B. A., Mwangi, J. W., Boykin Okalebo, L., Stanton, J-A. L., Black, A., Waipara, N., Fontsere, C., Eccles, D., Urel, H., Reska, T., Morales, H. E., Palmada-Flores, M., Marques-Bonet, T., Watsa, M., Libke, Z., ... van Oosterhout, C. (2023). Real-time genomics for One Health. Molecular Systems Biology, 19(8), [e11686]. https://doi.org/10.15252/msb.202311686

Vancouver

Urban L, Perlas A, Francino O, Martí-Carreras J, Muga BA, Mwangi JW et al. Real-time genomics for One Health. Molecular Systems Biology. 2023;19(8). e11686. https://doi.org/10.15252/msb.202311686

Author

Urban, Lara ; Perlas, Albert ; Francino, Olga ; Martí-Carreras, Joan ; Muga, Brenda A. ; Mwangi, Jenniffer W. ; Boykin Okalebo, Laura ; Stanton, Jo-Ann L. ; Black, Amanda ; Waipara, Nick ; Fontsere, Claudia ; Eccles, David ; Urel, Harika ; Reska, Tim ; Morales, Hernán E. ; Palmada-Flores, Marc ; Marques-Bonet, Tomas ; Watsa, Mrinalini ; Libke, Zane ; Erkenswick, Gideon ; van Oosterhout, Cock. / Real-time genomics for One Health. In: Molecular Systems Biology. 2023 ; Vol. 19, No. 8.

Bibtex

@article{2701c46c883f45698f550884525b3896,

title = "Real-time genomics for One Health",

abstract = "The ongoing degradation of natural systems and other environmental changes has put our society at a crossroad with respect to our future relationship with our planet. While the concept of One Health describes how human health is inextricably linked with environmental health, many of these complex interdependencies are still not well-understood. Here, we describe how the advent of real-time genomic analyses can benefit One Health and how it can enable timely, in-depth ecosystem health assessments. We introduce nanopore sequencing as the only disruptive technology that currently allows for real-time genomic analyses and that is already being used worldwide to improve the accessibility and versatility of genomic sequencing. We showcase real-time genomic studies on zoonotic disease, food security, environmental microbiome, emerging pathogens, and their antimicrobial resistances, and on environmental health itself – from genomic resource creation for wildlife conservation to the monitoring of biodiversity, invasive species, and wildlife trafficking. We stress why equitable access to real-time genomics in the context of One Health will be paramount and discuss related practical, legal, and ethical limitations.",

keywords = "global health, nanopore sequencing, nature conservation, One Health, real-time genomics",

author = "Lara Urban and Albert Perlas and Olga Francino and Joan Mart{\'i}-Carreras and Muga, {Brenda A.} and Mwangi, {Jenniffer W.} and {Boykin Okalebo}, Laura and Stanton, {Jo-Ann L.} and Amanda Black and Nick Waipara and Claudia Fontsere and David Eccles and Harika Urel and Tim Reska and Morales, {Hern{\'a}n E.} and Marc Palmada-Flores and Tomas Marques-Bonet and Mrinalini Watsa and Zane Libke and Gideon Erkenswick and {van Oosterhout}, Cock",

note = "Publisher Copyright: {\textcopyright} 2023 The Authors. Published under the terms of the CC BY 4.0 license.",

year = "2023",

doi = "10.15252/msb.202311686",

language = "English",

volume = "19",

journal = "Molecular Systems Biology",

issn = "1744-4292",

publisher = "Wiley-Blackwell",

number = "8",

}

RIS

TY - JOUR

T1 - Real-time genomics for One Health

AU - Urban, Lara

AU - Perlas, Albert

AU - Francino, Olga

AU - Martí-Carreras, Joan

AU - Muga, Brenda A.

AU - Mwangi, Jenniffer W.

AU - Boykin Okalebo, Laura

AU - Stanton, Jo-Ann L.

AU - Black, Amanda

AU - Waipara, Nick

AU - Fontsere, Claudia

AU - Eccles, David

AU - Urel, Harika

AU - Reska, Tim

AU - Morales, Hernán E.

AU - Palmada-Flores, Marc

AU - Marques-Bonet, Tomas

AU - Watsa, Mrinalini

AU - Libke, Zane

AU - Erkenswick, Gideon

AU - van Oosterhout, Cock

PY - 2023

Y1 - 2023

N2 - The ongoing degradation of natural systems and other environmental changes has put our society at a crossroad with respect to our future relationship with our planet. While the concept of One Health describes how human health is inextricably linked with environmental health, many of these complex interdependencies are still not well-understood. Here, we describe how the advent of real-time genomic analyses can benefit One Health and how it can enable timely, in-depth ecosystem health assessments. We introduce nanopore sequencing as the only disruptive technology that currently allows for real-time genomic analyses and that is already being used worldwide to improve the accessibility and versatility of genomic sequencing. We showcase real-time genomic studies on zoonotic disease, food security, environmental microbiome, emerging pathogens, and their antimicrobial resistances, and on environmental health itself – from genomic resource creation for wildlife conservation to the monitoring of biodiversity, invasive species, and wildlife trafficking. We stress why equitable access to real-time genomics in the context of One Health will be paramount and discuss related practical, legal, and ethical limitations.

AB - The ongoing degradation of natural systems and other environmental changes has put our society at a crossroad with respect to our future relationship with our planet. While the concept of One Health describes how human health is inextricably linked with environmental health, many of these complex interdependencies are still not well-understood. Here, we describe how the advent of real-time genomic analyses can benefit One Health and how it can enable timely, in-depth ecosystem health assessments. We introduce nanopore sequencing as the only disruptive technology that currently allows for real-time genomic analyses and that is already being used worldwide to improve the accessibility and versatility of genomic sequencing. We showcase real-time genomic studies on zoonotic disease, food security, environmental microbiome, emerging pathogens, and their antimicrobial resistances, and on environmental health itself – from genomic resource creation for wildlife conservation to the monitoring of biodiversity, invasive species, and wildlife trafficking. We stress why equitable access to real-time genomics in the context of One Health will be paramount and discuss related practical, legal, and ethical limitations.

KW - global health

KW - nanopore sequencing

KW - nature conservation

KW - One Health

KW - real-time genomics

U2 - 10.15252/msb.202311686

DO - 10.15252/msb.202311686

M3 - Review

C2 - 37325891

AN - SCOPUS:85161992859

VL - 19

JO - Molecular Systems Biology

JF - Molecular Systems Biology

SN - 1744-4292

IS - 8

M1 - e11686

ER -

ID: 358094389

Globe Institute