Unravelling animal–microbiota evolution on a chip

Research output: Contribution to journal › Review › Research › peer-review

Standard

Unravelling animal–microbiota evolution on a chip. / Aizpurua, Ostaizka; Blijleven, Kees; Trivedi, Urvish; Gilbert, M. Thomas P.; Alberdi, Antton.

In: Trends in Microbiology, Vol. 31, No. 10, 2023, p. 995-1002.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Aizpurua, O, Blijleven, K, Trivedi, U, Gilbert, MTP & Alberdi, A 2023, 'Unravelling animal–microbiota evolution on a chip', Trends in Microbiology, vol. 31, no. 10, pp. 995-1002. https://doi.org/10.1016/j.tim.2023.04.010

APA

Aizpurua, O., Blijleven, K., Trivedi, U., Gilbert, M. T. P., & Alberdi, A. (2023). Unravelling animal–microbiota evolution on a chip. Trends in Microbiology, 31(10), 995-1002. https://doi.org/10.1016/j.tim.2023.04.010

Vancouver

Aizpurua O, Blijleven K, Trivedi U, Gilbert MTP, Alberdi A. Unravelling animal–microbiota evolution on a chip. Trends in Microbiology. 2023;31(10):995-1002. https://doi.org/10.1016/j.tim.2023.04.010

Author

Aizpurua, Ostaizka ; Blijleven, Kees ; Trivedi, Urvish ; Gilbert, M. Thomas P. ; Alberdi, Antton. / Unravelling animal–microbiota evolution on a chip. In: Trends in Microbiology. 2023 ; Vol. 31, No. 10. pp. 995-1002.

Bibtex

@article{87c49efc14b44f458fa778087e41d3bd,

title = "Unravelling animal–microbiota evolution on a chip",

abstract = "Whether and how microorganisms have shaped the evolution of their animal hosts is a major question in biology. Although many animal evolutionary processes appear to correlate with changes in their associated microbial communities, the mechanistic processes leading to these patterns and their causal relationships are still far from being resolved. Gut-on-a-chip models provide an innovative approach that expands beyond the potential of conventional microbiome profiling to study how different animals sense and react to microbes by comparing responses of animal intestinal tissue models to different microbial stimuli. This complementary knowledge can contribute to our understanding of how host genetic features facilitate or prevent different microbiomes from being assembled, and in doing so elucidate the role of host–microbiota interactions in animal evolution.",

keywords = "gut-on-a-chip, host–microbiota interactions, in vitro models, MAMPs, PRRs",

author = "Ostaizka Aizpurua and Kees Blijleven and Urvish Trivedi and Gilbert, {M. Thomas P.} and Antton Alberdi",

note = "Publisher Copyright: {\textcopyright} 2023 Elsevier Ltd",

year = "2023",

doi = "10.1016/j.tim.2023.04.010",

language = "English",

volume = "31",

pages = "995--1002",

journal = "Trends in Microbiology",

issn = "0966-842X",

publisher = "Elsevier Ltd. * Trends Journals",

number = "10",

}

RIS

TY - JOUR

T1 - Unravelling animal–microbiota evolution on a chip

AU - Aizpurua, Ostaizka

AU - Blijleven, Kees

AU - Trivedi, Urvish

AU - Gilbert, M. Thomas P.

AU - Alberdi, Antton

PY - 2023

Y1 - 2023

N2 - Whether and how microorganisms have shaped the evolution of their animal hosts is a major question in biology. Although many animal evolutionary processes appear to correlate with changes in their associated microbial communities, the mechanistic processes leading to these patterns and their causal relationships are still far from being resolved. Gut-on-a-chip models provide an innovative approach that expands beyond the potential of conventional microbiome profiling to study how different animals sense and react to microbes by comparing responses of animal intestinal tissue models to different microbial stimuli. This complementary knowledge can contribute to our understanding of how host genetic features facilitate or prevent different microbiomes from being assembled, and in doing so elucidate the role of host–microbiota interactions in animal evolution.

AB - Whether and how microorganisms have shaped the evolution of their animal hosts is a major question in biology. Although many animal evolutionary processes appear to correlate with changes in their associated microbial communities, the mechanistic processes leading to these patterns and their causal relationships are still far from being resolved. Gut-on-a-chip models provide an innovative approach that expands beyond the potential of conventional microbiome profiling to study how different animals sense and react to microbes by comparing responses of animal intestinal tissue models to different microbial stimuli. This complementary knowledge can contribute to our understanding of how host genetic features facilitate or prevent different microbiomes from being assembled, and in doing so elucidate the role of host–microbiota interactions in animal evolution.

KW - gut-on-a-chip

KW - host–microbiota interactions

KW - in vitro models

KW - MAMPs

KW - PRRs

U2 - 10.1016/j.tim.2023.04.010

DO - 10.1016/j.tim.2023.04.010

M3 - Review

C2 - 37217368

AN - SCOPUS:85159913735

VL - 31

SP - 995

EP - 1002

JO - Trends in Microbiology

JF - Trends in Microbiology

SN - 0966-842X

IS - 10

ER -

ID: 350910069

Globe Institute