Ancient and modern genomes unravel the evolutionary history of the rhinoceros family
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
Ancient and modern genomes unravel the evolutionary history of the rhinoceros family. / Liu, Shanlin; Westbury, Michael V.; Dussex, Nicolas; Mitchell, Kieren J.; Sinding, Mikkel Holger S.; Heintzman, Peter D.; Duchêne, David A.; Kapp, Joshua D.; von Seth, Johanna; Heiniger, Holly; Sánchez-Barreiro, Fátima; Margaryan, Ashot; André-Olsen, Remi; De Cahsan, Binia; Meng, Guanliang; Yang, Chentao; Chen, Lei; van der Valk, Tom; Moodley, Yoshan; Rookmaaker, Kees; Bruford, Michael W.; Ryder, Oliver; Steiner, Cynthia; Sonsbeek, Linda G. R. Bruins-van; Vartanyan, Sergey; Guo, Chunxue; Cooper, Alan; Kosintsev, Pavel; Kirillova, Irina; Lister, Adrian M.; Marques-Bonet, Tomas; Gopalakrishnan, Shyam; Dunn, Robert R.; Lorenzen, Eline D.; Shapiro, Beth; Zhang, Guojie; Antoine, Pierre Olivier; Dalén, Love; Gilbert, M. Thomas P.
In: Cell, Vol. 184, No. 19, 2021, p. 4874-4885.e16.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Ancient and modern genomes unravel the evolutionary history of the rhinoceros family
AU - Liu, Shanlin
AU - Westbury, Michael V.
AU - Dussex, Nicolas
AU - Mitchell, Kieren J.
AU - Sinding, Mikkel Holger S.
AU - Heintzman, Peter D.
AU - Duchêne, David A.
AU - Kapp, Joshua D.
AU - von Seth, Johanna
AU - Heiniger, Holly
AU - Sánchez-Barreiro, Fátima
AU - Margaryan, Ashot
AU - André-Olsen, Remi
AU - De Cahsan, Binia
AU - Meng, Guanliang
AU - Yang, Chentao
AU - Chen, Lei
AU - van der Valk, Tom
AU - Moodley, Yoshan
AU - Rookmaaker, Kees
AU - Bruford, Michael W.
AU - Ryder, Oliver
AU - Steiner, Cynthia
AU - Sonsbeek, Linda G. R. Bruins-van
AU - Vartanyan, Sergey
AU - Guo, Chunxue
AU - Cooper, Alan
AU - Kosintsev, Pavel
AU - Kirillova, Irina
AU - Lister, Adrian M.
AU - Marques-Bonet, Tomas
AU - Gopalakrishnan, Shyam
AU - Dunn, Robert R.
AU - Lorenzen, Eline D.
AU - Shapiro, Beth
AU - Zhang, Guojie
AU - Antoine, Pierre Olivier
AU - Dalén, Love
AU - Gilbert, M. Thomas P.
N1 - Publisher Copyright: © 2021 The Authors
PY - 2021
Y1 - 2021
N2 - Only five species of the once-diverse Rhinocerotidae remain, making the reconstruction of their evolutionary history a challenge to biologists since Darwin. We sequenced genomes from five rhinoceros species (three extinct and two living), which we compared to existing data from the remaining three living species and a range of outgroups. We identify an early divergence between extant African and Eurasian lineages, resolving a key debate regarding the phylogeny of extant rhinoceroses. This early Miocene (∼16 million years ago [mya]) split post-dates the land bridge formation between the Afro-Arabian and Eurasian landmasses. Our analyses also show that while rhinoceros genomes in general exhibit low levels of genome-wide diversity, heterozygosity is lowest and inbreeding is highest in the modern species. These results suggest that while low genetic diversity is a long-term feature of the family, it has been particularly exacerbated recently, likely reflecting recent anthropogenic-driven population declines.
AB - Only five species of the once-diverse Rhinocerotidae remain, making the reconstruction of their evolutionary history a challenge to biologists since Darwin. We sequenced genomes from five rhinoceros species (three extinct and two living), which we compared to existing data from the remaining three living species and a range of outgroups. We identify an early divergence between extant African and Eurasian lineages, resolving a key debate regarding the phylogeny of extant rhinoceroses. This early Miocene (∼16 million years ago [mya]) split post-dates the land bridge formation between the Afro-Arabian and Eurasian landmasses. Our analyses also show that while rhinoceros genomes in general exhibit low levels of genome-wide diversity, heterozygosity is lowest and inbreeding is highest in the modern species. These results suggest that while low genetic diversity is a long-term feature of the family, it has been particularly exacerbated recently, likely reflecting recent anthropogenic-driven population declines.
KW - Rhinoceros, Perissodactyl, Conservation genomics, Phylogenomics, Genomic diversity
U2 - 10.1016/j.cell.2021.07.032
DO - 10.1016/j.cell.2021.07.032
M3 - Journal article
C2 - 34433011
AN - SCOPUS:85115014672
VL - 184
SP - 4874-4885.e16
JO - Cell
JF - Cell
SN - 0092-8674
IS - 19
ER -
ID: 281216987